Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues

por Coxon, Geoffrey D., Craig, Derek, Corrales, Rosa Milagros, Vialla, Emilie, Gannoun-Zaki, Laila, Kremer, Laurent
Publicado 2013

Synthesis and crystal structures of 3-hy­droxy-2,4-dimethyl-2H-thio­phen-5-one and 3-hy­droxy-4-methyl-2H-thio­phen-5-one

por Nashawi, Asma, Lawson, Christopher P., Abdel-Sattar, M. Omar, ter Horst, Joop H., Coxon, Geoffrey D., Kennedy, Alan R.
Publicado 2020

Thiacetazone, an Antitubercular Drug that Inhibits Cyclopropanation of Cell Wall Mycolic Acids in Mycobacteria

por Alahari, Anuradha, Trivelli, Xavier, Guérardel, Yann, Dover, Lynn G., Besra, Gurdyal S., Sacchettini, James C., Reynolds, Robert C., Coxon, Geoffrey D., Kremer, Laurent
Publicado 2007

Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H(37)R(v) and the β-Ketoacyl-ACP Synthase mtFabH

por Al-Balas, Qosay, Anthony, Nahoum G., Al-Jaidi, Bilal, Alnimr, Amani, Abbott, Grainne, Brown, Alistair K., Taylor, Rebecca C., Besra, Gurdyal S., McHugh, Timothy D., Gillespie, Stephen H., Johnston, Blair F., Mackay, Simon P., Coxon, Geoffrey D.
Publicado 2009