Systemic Treatment-Decision Algorithms in Muscle-Invasive Bladder Cancer: Clinical Complexities and Navigating for Improved Outcomes

por Giles, Megan, Crabb, Simon J
Publicado 2023

Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer

por Whitton, Bradleigh, Okamoto, Haruko, Packham, Graham, Crabb, Simon J.
Publicado 2018

Epigenetic modulators as therapeutic targets in prostate cancer

por Graça, Inês, Pereira-Silva, Eva, Henrique, Rui, Packham, Graham, Crabb, Simon J., Jerónimo, Carmen
Publicado 2016

Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue...

por Crabb, Simon J, Bajdik, Chris D, Leung, Samuel, Speers, Caroline H, Kennecke, Hagen, Huntsman, David G, Gelmon, Karen A
Publicado 2008

Clinical characteristics and outcomes for patients with non‑metastatic castration-resistant prostate cancer

por Arnold, Peter, Penaloza-Ramos, Maria Cristina, Adedokun, Lola, Rees, Sarah, Lockhat, Mohamed, Spary, Lisa, Watkins, Alan, Gnanapragasam, Vincent, Crabb, Simon J.
Publicado 2021

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer

por Crabb, Simon J., Birtle, Alison J., Martin, Karen, Downs, Nichola, Ratcliffe, Ian, Maishman, Tom, Ellis, Mary, Griffiths, Gareth, Thompson, Stuart, Ksiazek, Lidia, Khoo, Vincent, Jones, Robert J.
Publicado 2017

The Prognostic Role of the Change in Neutrophil-to-Lymphocyte Ratio During Neoadjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer: A Retrospective, Multi-Institut...

por Kaiser, Jeenan, Li, Haocheng, North, Scott A., Leibowitz-Amit, Raya, Seah, Jo-An, Morshed, Nisha, Chau, Caroline, Lee-Ying, Richard, Heng, Daniel Y.C., Sridhar, Srikala, Crabb, Simon J., Alimohamed, Nimira S.
Publicado 2018

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models

por Regufe da Mota, Sergio, Bailey, Sarah, Strivens, Rosemary A., Hayden, Annette L., Douglas, Leon R., Duriez, Patrick J., Borrello, M. Teresa, Benelkebir, Hanae, Ganesan, A., Packham, Graham, Crabb, Simon J.
Publicado 2018

Persistent Neutrophil to Lymphocyte Ratio >3 during Treatment with Enzalutamide and Clinical Outcome in Patients with Castration-Resistant Prostate Cancer

por Conteduca, Vincenza, Crabb, Simon J., Jones, Robert J., Caffo, Orazio, Elliott, Tony, Scarpi, Emanuela, Fabbri, Paolo, Derosa, Lisa, Massari, Francesco, Numico, Gianmauro, Zarif, Sunnya, Hanna, Catherine, Maines, Francesca, Joyce, Helen, Lolli, Cristian, De Giorgi, Ugo
Publicado 2016

Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

por Lolli, Cristian, Basso, Umberto, Derosa, Lisa, Scarpi, Emanuela, Sava, Teodoro, Santoni, Matteo, Crabb, Simon J., Massari, Francesco, Aieta, Michele, Conteduca, Vincenza, Maruzzo, Marco, La Russa, Francesca, Wheater, Matthew, Berardi, Rossana, Galli, Luca, De Giorgi, Ugo
Publicado 2016

Body Mass Index in Patients Treated with Cabozantinib for Advanced Renal Cell Carcinoma: A New Prognostic Factor?

por Santoni, Matteo, Massari, Francesco, Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, De Giorgi, Ugo, Basso, Umberto, Aurilio, Gaetano, Incorvaia, Lorena, Martignetti, Angelo, Rizzo, Mimma, Cartenì, Giacomo, Grande, Enrique, Matrana, Marc R., Crabb, Simon J., Vau, Nuno, Sorgentoni, Giulia, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
Publicado 2021

A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Ur...

por Crabb, Simon J., Hussain, Syed, Soulis, Eileen, Hinsley, Samantha, Dempsey, Laura, Trevethan, Avril, Song, YeePei, Barber, Jim, Frew, John, Gale, Joanna, Faust, Guy, Brock, Susannah, McGovern, Ursula, Parikh, Omi, Enting, Deborah, Sundar, Santhanam, Ratnayake, Gihan, Lees, Kathryn, Birtle, Alison J., Powles, Thomas, Jones, Robert J.
Publicado 2023

Venous thromboembolism in metastatic urothelial carcinoma or variant histologies: incidence, associative factors, and effect on survival

por Ramos, Jorge D., Casey, Martin F., Crabb, Simon J., Bamias, Aristotelis, Harshman, Lauren C., Wong, Yu‐Ning, Bellmunt, Joaquim, De Giorgi, Ugo, Ladoire, Sylvain, Powles, Thomas, Pal, Sumanta K., Niegisch, Guenter, Recine, Federica, Alva, Ajjai, Agarwal, Neeraj, Necchi, Andrea, Vaishampayan, Ulka N., Rosenberg, Jonathan E., Galsky, Matthew D., Yu, Evan Y.
Publicado 2016

COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss

por Crabb, Simon J., Martin, Karen, Abab, Julia, Ratcliffe, Ian, Thornton, Roger, Lineton, Ben, Ellis, Mary, Moody, Ronald, Stanton, Louise, Galanopoulou, Angeliki, Maishman, Tom, Geldart, Thomas, Bayne, Mike, Davies, Joe, Lamb, Carolynn, Popat, Sanjay, Joffe, Johnathan K., Nutting, Chris, Chester, John, Hartley, Andrew, Thomas, Gareth, Ottensmeier, Christian, Huddart, Robert, King, Emma
Publicado 2017

Neoadjuvant vs. Adjuvant Chemotherapy in Muscle Invasive Bladder Cancer (MIBC): Analysis From the RISC Database

por Del Bene, Gabriella, Calabrò, Fabio, Giannarelli, Diana, Plimack, Elizabeth R., Harshman, Lauren C., Yu, Evan Y., Crabb, Simon J., Pal, Sumanta Kumar, Alva, Ajjai S., Powles, Thomas, De Giorgi, Ugo, Agarwal, Neeraj, Bamias, Aristotelis, Ladoire, Sylvain, Necchi, Andrea, Vaishampayan, Ulka N., Niegisch, Günter, Bellmunt, Joaquim, Baniel, Jack, Galsky, Matthew D., Sternberg, Cora N.
Publicado 2018

Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID)

por Crabb, Simon J., Griffiths, Gareth, Marwood, Ellice, Dunkley, Denise, Downs, Nichola, Martin, Karen, Light, Michelle, Northey, Josh, Wilding, Sam, Whitehead, Amy, Shaw, Emily, Birtle, Alison J., Bahl, Amit, Elliott, Tony, Westbury, Charlotte, Sundar, Santhanam, Robinson, Angus, Jagdev, Satinder, Kumar, Satish, Rooney, Claire, Salinas-Souza, Carolina, Stephens, Christine, Khoo, Vincent, Jones, Robert J.
Publicado 2021

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

por de Jong, Joep J., Liu, Yang, Robertson, A. Gordon, Seiler, Roland, Groeneveld, Clarice S., van der Heijden, Michiel S., Wright, Jonathan L., Douglas, James, Dall’Era, Marc, Crabb, Simon J., van Rhijn, Bas W. G., van Kessel, Kim E. M., Davicioni, Elai, Castro, Mauro A. A., Lotan, Yair, Zwarthoff, Ellen C., Black, Peter C., Boormans, Joost L., Gibb, Ewan A.
Publicado 2019

Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic Factors

por Santoni, Matteo, Heng, Daniel Y., Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, Porta, Camillo, Matrana, Marc R., Cartenì, Giacomo, Crabb, Simon J., De Giorgi, Ugo, Basso, Umberto, Masini, Cristina, Calabrò, Fabio, Vitale, Maria Giuseppa, Santini, Daniele, Massari, Francesco, Galli, Luca, Fornarini, Giuseppe, Ricotta, Riccardo, Buti, Sebastiano, Zucali, Paolo, Caffo, Orazio, Morelli, Franco, Carrozza, Francesco, Martignetti, Angelo, Gelibter, Alain, Iacovelli, Roberto, Mosca, Alessandra, Atzori, Francesco, Vau, Nuno, Incorvaia, Lorena, Ortega, Cinzia, Scarpelli, Marina, Lopez-Beltran, Antonio, Cheng, Liang, Paolucci, Vittorio, Graham, Jeffrey, Pierce, Erin, Scagliarini, Sarah, Sepe, Pierangela, Verzoni, Elena, Merler, Sara, Rizzo, Mimma, Sorgentoni, Giulia, Conti, Alessandro, Piva, Francesco, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
Publicado 2019