The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells

por Lee, Ciaran M, Cradick, Thomas J, Bao, Gang
Publicado 2016

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

por Cradick, Thomas J., Fine, Eli J., Antico, Christopher J., Bao, Gang
Publicado 2013

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

por Lee, Ciaran M, Cradick, Thomas J, Fine, Eli J, Bao, Gang
Publicado 2016

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

por Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P
Publicado 2011

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

por Fine, Eli J., Cradick, Thomas J., Zhao, Charles L., Lin, Yanni, Bao, Gang
Publicado 2014

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

por Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang
Publicado 2014

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

por Mussolino, Claudio, Alzubi, Jamal, Fine, Eli J., Morbitzer, Robert, Cradick, Thomas J., Lahaye, Thomas, Bao, Gang, Cathomen, Toni
Publicado 2014

SAPTA: a new design tool for improving TALE nuclease activity

por Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Publicado 2014

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

por Lin, Yanni, Cradick, Thomas J., Brown, Matthew T., Deshmukh, Harshavardhan, Ranjan, Piyush, Sarode, Neha, Wile, Brian M., Vertino, Paula M., Stewart, Frank J., Bao, Gang
Publicado 2014

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

por Ramirez, Cherie L., Certo, Michael T., Mussolino, Claudio, Goodwin, Mathew J., Cradick, Thomas J., McCaffrey, Anton P., Cathomen, Toni, Scharenberg, Andrew M., Joung, J. Keith
Publicado 2012

In vivo genome editing at the albumin locus to treat methylmalonic acidemia

por Schneller, Jessica L., Lee, Ciaran M., Venturoni, Leah E., Chandler, Randy J., Li, Ang, Myung, Sangho, Cradick, Thomas J., Hurley, Ayrea E., Lagor, William R., Bao, Gang, Venditti, Charles P.
Publicado 2021

Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells

por Liu, Hong, Chen, Chen, Liao, Shuren, Sohaii, Danielle K., Cruz, Conrad R.Y., Burdo, Tricia H., Cradick, Thomas J., Mehta, Anand, Barrero, Carlos, Florez, Magda, Gordon, Jennifer, Grauzam, Stephane, Dressman, James, Amini, Shohreh, Bollard, Catherine M., Kaminski, Rafal, Khalili, Kamel
Publicado 2023

Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods

por Chaudhari, Hemangi G., Penterman, Jon, Whitton, Holly J., Spencer, Sarah J., Flanagan, Nicole, Lei Zhang, Maria C., Huang, Elaine, Khedkar, Aditya S., Toomey, J. Mike, Shearer, Courtney A., Needham, Alexander W., Ho, Tony W., Kulman, John D., Cradick, T.J., Kernytsky, Andrew
Publicado 2020

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

por Suzuki, Shingo, Sargent, R Geoffrey, Illek, Beate, Fischer, Horst, Esmaeili-Shandiz, Alaleh, Yezzi, Michael J, Lee, Albert, Yang, Yanu, Kim, Soya, Renz, Peter, Qi, Zhongxia, Yu, Jingwei, Muench, Marcus O, Beyer, Ashley I, Guimarães, Alessander O, Ye, Lin, Chang, Judy, Fine, Eli J, Cradick, Thomas J, Bao, Gang, Rahdar, Meghdad, Porteus, Matthew H, Shuto, Tsuyoshi, Kai, Hirofumi, Kan, Yuet W, Gruenert, Dieter C
Publicado 2016