ATRX is a regulator of therapy induced senescence in human cells

por Kovatcheva, Marta, Liao, Will, Klein, Mary E., Robine, Nicolas, Geiger, Heather, Crago, Aimee M., Dickson, Mark A., Tap, William D., Singer, Samuel, Koff, Andrew
Publicado 2017

The miR-17-92 Cluster and Its Target THBS1 Are Differentially Expressed in Angiosarcomas Dependent on MYC Amplification

por Italiano, Antoine, Thomas, Rachael, Breen, Matthew, Zhang, Lei, Crago, Aimee M, Singer, Samuel, Khanin, Raya, Maki, Robert G, Mihailovic, Aleksandra, Hafner, Markus, Tuschl, Tom, Antonescu, Cristina R
Publicado 2012

Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

por Chmielecki, Juliann, Crago, Aimee M., Rosenberg, Mara, O'Connor, Rachael, Walker, Sarah R., Ambrogio, Lauren, Auclair, Daniel, McKenna, Aaron, Heinrich, Michael C., Frank, David A., Meyerson, Matthew
Publicado 2013

PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence

por Klein, Mary E., Dickson, Mark A., Antonescu, Cristina, Qin, Li-Xuan, Dooley, Scott J., Barlas, Afsar, Manova, Katia, Schwartz, Gary K., Crago, Aimee M., Singer, Samuel, Koff, Andrew, Tap, William D.
Publicado 2018

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition

por Kovatcheva, Marta, Liu, David D., Dickson, Mark A., Klein, Mary E., O'Connor, Rachael, Wilder, Fatima O., Socci, Nicholas D., Tap, William D., Schwartz, Gary K., Singer, Samuel, Crago, Aimee M., Koff, Andrew
Publicado 2015

Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors

por Chi, Ping, Qin, Li-Xuan, Camacho, Niedzica, Kelly, Ciara M., D'Angelo, Sandra P., Dickson, Mark A., Gounder, Mrinal M., Keohan, Mary L., Movva, Sujana, Nacev, Benjamin A., Rosenbaum, Evan, Thornton, Katherine A., Crago, Aimee M., Francis, Jasmine H., Martindale, Moriah, Phelan, Haley T., Biniakewitz, Matthew D., Lee, Cindy J., Singer, Samuel, Hwang, Sinchun, Berger, Michael F., Chen, Yu, Antonescu, Cristina R., Tap, William D.
Publicado 2022

The association between tumor mutational burden and prognosis is dependent on treatment context

por Valero, Cristina, Lee, Mark, Hoen, Douglas, Wang, Jingming, Nadeem, Zaineb, Patel, Neal, Postow, Michael A., Shoushtari, Alexander N., Plitas, George, Balachandran, Vinod P., Smith, J. Joshua, Crago, Aimee M., Roche, Kara C. Long, Kelly, Daniel W., Samstein, Robert M., Rana, Satshil, Ganly, Ian, Wong, Richard J., Hakimi, A. Ari, Berger, Michael F., Zehir, Ahmet, Solit, David B., Ladanyi, Marc, Riaz, Nadeem, Chan, Timothy A., Seshan, Venkatraman E., Morris, Luc G.T.
Publicado 2021

Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors

por Valero, Cristina, Lee, Mark, Hoen, Douglas, Weiss, Kate, Kelly, Daniel W., Adusumilli, Prasad S., Paik, Paul K., Plitas, George, Ladanyi, Marc, Postow, Michael A., Ariyan, Charlotte E., Shoushtari, Alexander N., Balachandran, Vinod P., Hakimi, A. Ari, Crago, Aimee M., Long Roche, Kara C., Smith, J. Joshua, Ganly, Ian, Wong, Richard J., Patel, Snehal G., Shah, Jatin P., Lee, Nancy Y., Riaz, Nadeem, Wang, Jingming, Zehir, Ahmet, Berger, Michael F., Chan, Timothy A., Seshan, Venkatraman E., Morris, Luc G. T.
Publicado 2021

Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets

por Nacev, Benjamin A., Sanchez-Vega, Francisco, Smith, Shaleigh A., Antonescu, Cristina R., Rosenbaum, Evan, Shi, Hongyu, Tang, Cerise, Socci, Nicholas D., Rana, Satshil, Gularte-Mérida, Rodrigo, Zehir, Ahmet, Gounder, Mrinal M., Bowler, Timothy G., Luthra, Anisha, Jadeja, Bhumika, Okada, Azusa, Strong, Jonathan A., Stoller, Jake, Chan, Jason E., Chi, Ping, D’Angelo, Sandra P., Dickson, Mark A., Kelly, Ciara M., Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Meyers, Paul A., Wexler, Leonard H., Slotkin, Emily K., Glade Bender, Julia L., Shukla, Neerav N., Hensley, Martee L., Healey, John H., La Quaglia, Michael P., Alektiar, Kaled M., Crago, Aimee M., Yoon, Sam S., Untch, Brian R., Chiang, Sarah, Agaram, Narasimhan P., Hameed, Meera R., Berger, Michael F., Solit, David B., Schultz, Nikolaus, Ladanyi, Marc, Singer, Samuel, Tap, William D.
Publicado 2022