Current and Potential Treatments for Ubiquitous but Neglected Herpesvirus Infections

por Gable, Jonathan E., Acker, Timothy M., Craik, Charles S.
Publicado 2014

Cullin E3 Ligases and Their Rewiring by Viral Factors

por Mahon, Cathal, Krogan, Nevan J., Craik, Charles S., Pick, Elah
Publicado 2014

Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity

por Jones, Stephen K., Clarke, Starlynn C., Craik, Charles S., Bennett, Richard J.
Publicado 2015

Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes

por Vasiljeva, Olga, Menendez, Elizabeth, Nguyen, Margaret, Craik, Charles S., Michael Kavanaugh, W.
Publicado 2020

In vivo imaging of protease activity by Probody therapeutic activation

por Wong, Kenneth R., Menendez, Elizabeth, Craik, Charles S., Kavanaugh, W. Michael, Vasiljeva, Olga
Publicado 2015

Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

por Lohse, Matthew B., Gulati, Megha, Craik, Charles S., Johnson, Alexander D., Nobile, Clarissa J.
Publicado 2020

Sensitive and Selective Plasmon Ruler Nanosensors for Monitoring the Apoptotic Drug Response in Leukemia

por Tajon, Cheryl A., Seo, Daeha, Asmussen, Jennifer, Shah, Neil, Jun, Young-wook, Craik, Charles S.
Publicado 2014

Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity

por Skala, Wolfgang, Utzschneider, Daniel T., Magdolen, Viktor, Debela, Mekdes, Craik, Charles S., Brandstetter, Hans, Goettig, Peter
Publicado 2014

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23

por Barkan, David T., Cheng, Xiao-li, Celino, Herodion, Tran, Tran T., Bhandari, Ashok, Craik, Charles S., Sali, Andrej, Smythe, Mark L.
Publicado 2016

Broad-Spectrum Allosteric Inhibition of Herpesvirus Proteases

por Gable, Jonathan E., Lee, Gregory M., Jaishankar, Priyadarshini, Hearn, Brian R., Waddling, Christopher A., Renslo, Adam R., Craik, Charles S.
Publicado 2014

Inhibition of a Viral Enzyme by a Small Molecule Dimer Disruptor

por Shahian, Tina, Lee, Gregory M., Lazic, Ana, Arnold, Leggy A., Velusamy, Priya, Roels, Christina M., Kiplin Guy, R., Craik, Charles S.
Publicado 2009

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria

por Goupil, Louise S., Ivry, Sam L., Hsieh, Ivy, Suzuki, Brian M., Craik, Charles S., O’Donoghue, Anthony J., McKerrow, James H.
Publicado 2016

Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts

por Suresh, Vallabh, Byers, Kaleb, Rajesh, Ummadisetti Chinna, Caiazza, Francesco, Zhu, Gina, Craik, Charles S., Kirkwood, Kimberly, Davisson, Vincent Jo, Sheik, Daniel A.
Publicado 2022

The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti()

por Dolečková, Kateřina, Kašný, Martin, Mikeš, Libor, Cartwright, Jared, Jedelský, Petr, Schneider, Eric L., Dvořák, Jan, Mountford, Adrian P., Craik, Charles S., Horák, Petr
Publicado 2009

Imaging the Urokinase Plasminongen Activator Receptor in Preclinical Breast Cancer Models of Acquired Drug Resistance

por LeBeau, Aaron M., Sevillano, Natalia, King, Mandy L., Duriseti, Sai, Murphy, Stephanie T., Craik, Charles S., Murphy, Laura L., VanBrocklin, Henry F.
Publicado 2014

4532 Pancreatic Cyst Risk Stratification for Early Detection of Pancreatic Cancer Using Quantitative Radiomics and Activity-Based Biomarkers

por Hernandez, Sophia, Lourenco, Andre Luiz, Calabrese, Evan, York, Tyler, Glencer, Alexa, Behr, Spencer, Wang, Zhen Jane, Koay, Eugene, Craik, Charles, Kirkwood, Kimberly
Publicado 2020

Global Substrate Profiling of Proteases in Human Neutrophil Extracellular Traps Reveals Consensus Motif Predominantly Contributed by Elastase

por O’Donoghue, Anthony J., Jin, Ye, Knudsen, Giselle M., Perera, Natascha C., Jenne, Dieter E., Murphy, John E., Craik, Charles S., Hermiston, Terry W.
Publicado 2013

Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystati...

por Dvořáková, Hana, Leontovyč, Roman, Macháček, Tomáš, O'Donoghue, Anthony J., Šedo, Ondřej, Zdráhal, Zbyněk, Craik, Charles S., Caffrey, Conor R., Horák, Petr, Mikeš, Libor
Publicado 2020

A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19

por Suresh, Vallabh, Sheik, Daniel A., Detomasi, Tyler C., Zhao, Tianqi, Zepeda, Theresa, Saladi, Shyam, Rajesh, Ummadisetti Chinna, Byers, Kaleb, Craik, Charles S., Davisson, Vincent Jo
Publicado 2023

A covalent inhibitor of K-Ras(G12C) induces MHC-I presentation of haptenated peptide neoepitopes targetable by immunotherapy

por Zhang, Ziyang, Rohweder, Peter J., Ongpipattanakul, Chayanid, Basu, Koli, Bohn, Markus F., Dugan, Eli J., Steri, Veronica, Hann, Byron, Shokat, Kevan M., Craik, Charles S.
Publicado 2022