Complement factor I and age-related macular degeneration

por Alexander, Philip, Gibson, Jane, Cree, Angela J., Ennis, Sarah, Lotery, Andrew J.
Publicado 2014

Epigenetic Age Acceleration Is Not Associated with Age-Related Macular Degeneration

por Saptarshi, Neil, Green, Daniel, Cree, Angela, Lotery, Andrew, Paraoan, Luminita, Porter, Louise F.
Publicado 2021

Chlamydia infection status, genotype, and age-related macular degeneration

por Khandhadia, Sam, Foster, Sebastian, Cree, Angela, Griffiths, Helen, Osmond, Clive, Goverdhan, Srinivas, Lotery, Andrew
Publicado 2012

The effect of systemic levels of TNF-alpha and complement pathway activity on outcomes of VEGF inhibition in neovascular AMD

por Khan, Adnan H., Pierce, Charles O., De Salvo, Gabriella, Griffiths, Helen, Nelson, Marie, Cree, Angela J., Menon, Geeta, Lotery, Andrew J.
Publicado 2021

Genome-wide association study of primary open angle glaucoma risk and quantitative traits

por Gibson, Jane, Griffiths, Helen, De Salvo, Gabriella, Cole, Mick, Jacob, Aby, MacLeod, Alex, Yang, Yit, Menon, Geeta, Cree, Angela, Ennis, Sarah, Lotery, Andrew
Publicado 2012

A novel, wearable, electronic visual aid to assist those with reduced peripheral vision

por Brown, Ffion E., Sutton, Janice, Yuen, Ho M., Green, Dylan, Van Dorn, Spencer, Braun, Terry, Cree, Angela J., Russell, Stephen R., Lotery, Andrew J.
Publicado 2019

Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration

por Hallam, Thomas M., Marchbank, Kevin J., Harris, Claire L., Osmond, Clive, Shuttleworth, Victoria G., Griffiths, Helen, Cree, Angela J., Kavanagh, David, Lotery, Andrew J.
Publicado 2020

Comprehensive sequencing of the myocilin gene in a selected cohort of severe primary open-angle glaucoma patients

por O’Gorman, Luke, Cree, Angela J., Ward, Daniel, Griffiths, Helen L., Sood, Roshan, Denniston, Alastair K., Self, Jay E., Ennis, Sarah, Lotery, Andrew J., Gibson, Jane
Publicado 2019

A convenient protocol for establishing a human cell culture model of the outer retina.

por Lynn, Savannah A., Keeling, Eloise, Dewing, Jennifer M., Johnston, David A., Page, Anton, Cree, Angela J., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2018

Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE

por Lynn, Savannah A., Ward, Gareth, Keeling, Eloise, Scott, Jenny A., Cree, Angela J., Johnston, David A., Page, Anton, Cuan-Urquizo, Enrique, Bhaskar, Atul, Grossel, Martin C., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2017

An Exploratory Study Provides Insights into MMP9 and Aβ Levels in the Vitreous and Blood across Different Ages and in a Subset of AMD Patients

por Lynn, Savannah A., Soubigou, Flavie, Dewing, Jennifer M., Smith, Amanda, Ballingall, Joanna, Sass, Thea, Nica, Isabela, Watkins, Catrin, Gupta, Bhaskar, Almuhtaseb, Hussein, Lash, Stephen C., Yuen, Ho Ming, Cree, Angela, Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2022

Correction: Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protoc...

por Sutton, Janice, Menten, Martin J., Riedl, Sophie, Bogunović, Hrvoje, Leingang, Oliver, Anders, Philipp, Hagag, Ahmed M., Waldstein, Sebastian, Wilson, Amber, Cree, Angela J., Traber, Ghislaine, Fritsche, Lars G., Scholl, Hendrik, Rueckert, Daniel, Schmidt-Erfurth, Ursula, Sivaprasad, Sobha, Prevost, Toby, Lotery, Andrew
Publicado 2022

A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping

por O’Gorman, Luke, Norman, Chelsea S., Michaels, Luke, Newall, Tutte, Crosby, Andrew H., Mattocks, Christopher, Cree, Angela J., Lotery, Andrew J., Baple, Emma L., Ratnayaka, J. Arjuna, Baralle, Diana, Lee, Helena, Osborne, Daniel, Shawkat, Fatima, Gibson, Jane, Ennis, Sarah, Self, Jay E.
Publicado 2019

Oligomeric Aβ(1-42) Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

por Lynn, Savannah A., Johnston, David A., Scott, Jenny A., Munday, Rosie, Desai, Roshni S., Keeling, Eloise, Weaterton, Ruaridh, Simpson, Alexander, Davis, Dillon, Freeman, Thomas, Chatelet, David S., Page, Anton, Cree, Angela J., Lee, Helena, Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2021

Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol

por Sutton, Janice, Menten, Martin J., Riedl, Sophie, Bogunović, Hrvoje, Leingang, Oliver, Anders, Philipp, Hagag, Ahmed M., Waldstein, Sebastian, Wilson, Amber, Cree, Angela J., Traber, Ghislaine, Fritsche, Lars G., Scholl, Hendrik, Rueckert, Daniel, Schmidt-Erfurth, Ursula, Sivaprasad, Sobha, Prevost, Toby, Lotery, Andrew
Publicado 2022

Prevalence and phenotype associations of complement factor I mutations in geographic atrophy

por Khan, Adnan H., Sutton, Janice, Cree, Angela J., Khandhadia, Samir, De Salvo, Gabriella, Tobin, John, Prakash, Priya, Arora, Rashi, Amoaku, Winfried, Charbel Issa, Peter, MacLaren, Robert E., Bishop, Paul N., Peto, Tunde, Mohamed, Quresh, Steel, David H., Sivaprasad, Sobha, Bailey, Clare, Menon, Geeta, Kavanagh, David, Lotery, Andrew J.
Publicado 2021

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

por Bonnemaijer, Pieter W. M., Leeuwen, Elisabeth M. van, Iglesias, Adriana I., Gharahkhani, Puya, Vitart, Veronique, Khawaja, Anthony P., Simcoe, Mark, Höhn, René, Cree, Angela J., Igo, Rob P., Gerhold-Ay, Aslihan, Nickels, Stefan, Wilson, James F., Hayward, Caroline, Boutin, Thibaud S., Polašek, Ozren, Aung, Tin, Khor, Chiea Chuen, Amin, Najaf, Lotery, Andrew J., Wiggs, Janey L., Cheng, Ching-Yu, Hysi, Pirro G., Hammond, Christopher J., Thiadens, Alberta A. H. J., MacGregor, Stuart, Klaver, Caroline C. W., Duijn, Cornelia M. van
Publicado 2019

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

por Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.
Publicado 2021

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

por Springelkamp, Henriët., Höhn, René, Mishra, Aniket, Hysi, Pirro G., Khor, Chiea-Chuen, Loomis, Stephanie J., Bailey, Jessica N. Cooke, Gibson, Jane, Thorleifsson, Gudmar, Janssen, Sarah F., Luo, Xiaoyan, Ramdas, Wishal D., Vithana, Eranga, Nongpiur, Monisha E., Montgomery, Grant W., Xu, Liang, Mountain, Jenny E., Gharahkhani, Puya, Lu, Yi, Amin, Najaf, Karssen, Lennart C., Sim, Kar-Seng, van Leeuwen, Elisabeth M., Iglesias, Adriana I., Verhoeven, Virginie J. M., Hauser, Michael A., Loon, Seng-Chee, Despriet, Dominiek D. G., Nag, Abhishek, Venturini, Cristina, Sanfilippo, Paul G., Schillert, Arne, Kang, Jae H., Landers, John, Jonasson, Fridbert, Cree, Angela J., van Koolwijk, Leonieke M. E., Rivadeneira, Fernando, Souzeau, Emmanuelle, Jonsson, Vesteinn, Menon, Geeta, Weinreb, Robert N., de Jong, Paulus T. V. M., Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Ennis, Sarah, Thorsteinsdottir, Unnur, Burdon, Kathryn P., Spector, Timothy D., Mirshahi, Alireza, Saw, Seang-Mei, Vingerling, Johannes R., Teo, Yik-Ying, Haines, Jonathan L., Wolfs, Roger C. W., Lemij, Hans G., Tai, E-Shyong, Jansonius, Nomdo M., Jonas, Jost B., Cheng, Ching-Yu, Aung, Tin, Viswanathan, Ananth C., Klaver, Caroline C. W., Craig, Jamie E., Macgregor, Stuart, Mackey, David A., Lotery, Andrew J., Stefansson, Kari, Bergen, Arthur A. B., Young, Terri L., Wiggs, Janey L., Pfeiffer, Norbert, Wong, Tien-Yin, Pasquale, Louis R., Hewitt, Alex W., van Duijn, Cornelia M., Hammond, Christopher J.
Publicado 2014

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

por Fritsche, Lars G., Igl, Wilmar, Cooke Bailey, Jessica N., Grassmann, Felix, Sengupta, Sebanti, Bragg-Gresham, Jennifer L., Burdon, Kathryn P., Hebbring, Scott J., Wen, Cindy, Gorski, Mathias, Kim, Ivana K., Cho, David, Zack, Donald, Souied, Eric, Scholl, Hendrik P. N., Bala, Elisa, Lee, Kristine E., Hunter, David J., Sardell, Rebecca J., Mitchell, Paul, Merriam, Joanna E., Cipriani, Valentina, Hoffman, Joshua D., Schick, Tina, Lechanteur, Yara T. E., Guymer, Robyn H., Johnson, Matthew P., Jiang, Yingda, Stanton, Chloe M., Buitendijk, Gabriëlle H. S., Zhan, Xiaowei, Kwong, Alan M., Boleda, Alexis, Brooks, Matthew, Gieser, Linn, Ratnapriya, Rinki, Branham, Kari E., Foerster, Johanna R., Heckenlively, John R., Othman, Mohammad I., Vote, Brendan J., Liang, Helena Hai, Souzeau, Emmanuelle, McAllister, Ian L., Isaacs, Timothy, Hall, Janette, Lake, Stewart, Mackey, David A., Constable, Ian J., Craig, Jamie E., Kitchner, Terrie E., Yang, Zhenglin, Su, Zhiguang, Luo, Hongrong, Chen, Daniel, Ouyang, Hong, Flagg, Ken, Lin, Danni, Mao, Guanping, Ferreyra, Henry, Stark, Klaus, von Strachwitz, Claudia N., Wolf, Armin, Brandl, Caroline, Rudolph, Guenther, Olden, Matthias, Morrison, Margaux A., Morgan, Denise J., Schu, Matthew, Ahn, Jeeyun, Silvestri, Giuliana, Tsironi, Evangelia E., Park, Kyu Hyung, Farrer, Lindsay A., Orlin, Anton, Brucker, Alexander, Li, Mingyao, Curcio, Christine, Mohand-Saïd, Saddek, Sahel, José-Alain, Audo, Isabelle, Benchaboune, Mustapha, Cree, Angela J., Rennie, Christina A., Goverdhan, Srinivas V., Grunin, Michelle, Hagbi-Levi, Shira, Campochiaro, Peter, Katsanis, Nicholas, Holz, Frank G., Blond, Frédéric, Blanché, Hélène, Deleuze, Jean-François, Igo, Robert P., Truitt, Barbara, Peachey, Neal S., Meuer, Stacy M., Myers, Chelsea E., Moore, Emily L., Klein, Ronald, Hauser, Michael A., Postel, Eric A., Courtenay, Monique D., Schwartz, Stephen G., Kovach, Jaclyn L., Scott, William K., Liew, Gerald, Tƒan, Ava G., Gopinath, Bamini, Merriam, John C., Smith, R. Theodore, Khan, Jane C., Shahid, Humma, Moore, Anthony T., McGrath, J. Allie, Laux, Reneé, Brantley, Milam A., Agarwal, Anita, Ersoy, Lebriz, Caramoy, Albert, Langmann, Thomas, Saksens, Nicole T. M., de Jong, Eiko K., Hoyng, Carel B., Cain, Melinda S., Richardson, Andrea J., Martin, Tammy M., Blangero, John, Weeks, Daniel E., Dhillon, Bal, van Duijn, Cornelia M., Doheny, Kimberly F., Romm, Jane, Klaver, Caroline C. W., Hayward, Caroline, Gorin, Michael B., Klein, Michael L., Baird, Paul N., den Hollander, Anneke I., Fauser, Sascha, Yates, John R. W., Allikmets, Rando, Wang, Jie Jin, Schaumberg, Debra A., Klein, Barbara E. K., Hagstrom, Stephanie A., Chowers, Itay, Lotery, Andrew J., Léveillard, Thierry, Zhang, Kang, Brilliant, Murray H., Hewitt, Alex W., Swaroop, Anand, Chew, Emily Y., Pericak-Vance, Margaret A., DeAngelis, Margaret, Stambolian, Dwight, Haines, Jonathan L., Iyengar, Sudha K., Weber, Bernhard H. F., Abecasis, Gonçalo R., Heid, Iris M.
Publicado 2015