A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery

por Creemers, Jeroen H A, Lesterhuis, W Joost, Mehra, Niven, Gerritsen, Winald R, Figdor, Carl G, de Vries, I Jolanda M, Textor, Johannes
Publicado 2021

In silico cancer immunotherapy trials uncover the consequences of therapy-specific response patterns for clinical trial design and outcome

por Creemers, Jeroen H. A., Ankan, Ankur, Roes, Kit C. B., Schröder, Gijs, Mehra, Niven, Figdor, Carl G., de Vries, I. Jolanda M., Textor, Johannes
Publicado 2023

Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-labe...

por Creemers, Jeroen H A, Pawlitzky, Inka, Grosios, Konstantina, Gileadi, Uzi, Middleton, Mark R, Gerritsen, Winald R, Mehra, Niven, Rivoltini, Licia, Walters, Ian, Figdor, Carl G, Ottevanger, Petronella B, de Vries, I Jolanda M
Publicado 2021

Immunophenotyping Reveals Longitudinal Changes in Circulating Immune Cells During Radium-223 Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer

por Creemers, Jeroen H. A., van der Doelen, Maarten J., van Wilpe, Sandra, Hermsen, Rick, Duiveman-de Boer, Tjitske, Somford, Diederik M., Janssen, Marcel J. R., Sedelaar, J. P. Michiel, Mehra, Niven, Textor, Johannes, Westdorp, Harm
Publicado 2021

Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients

por Boudewijns, Steve, Westdorp, Harm, Koornstra, Rutger H.T., Aarntzen, Erik H.J.G., Schreibelt, Gerty, Creemers, Jeroen H.A., Punt, Cornelis J.A., Figdor, Carl G., de Vries, I. Jolanda M., Gerritsen, Winald R., Bol, Kalijn F.
Publicado 2016

High Health-Related Quality of Life During Dendritic Cell Vaccination Therapy in Patients With Castration-Resistant Prostate Cancer

por Westdorp, Harm, Creemers, Jeroen H. A., van Oort, Inge M., Mehra, Niven, Hins-de Bree, Simone M., Figdor, Carl G., Witjes, J. Alfred, Schreibelt, Gerty, de Vries, I. Jolanda M., Gerritsen, Winald R., Ottevanger, Petronella B.
Publicado 2020

PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses

por Dölen, Yusuf, Gileadi, Uzi, Chen, Ji-Li, Valente, Michael, Creemers, Jeroen H. A., Van Dinther, Eric A. W., van Riessen, N. Koen, Jäger, Eliezer, Hruby, Martin, Cerundolo, Vincenzo, Diken, Mustafa, Figdor, Carl G., de Vries, I. Jolanda M.
Publicado 2021

Tumor microenvironment shows an immunological abscopal effect in patients with NSCLC treated with pembrolizumab-radiotherapy combination

por van der Woude, Lieke L, Gorris, Mark A J, Wortel, Inge M N, Creemers, Jeroen H A, Verrijp, Kiek, Monkhorst, Kim, Grünberg, Katrien, van den Heuvel, Michel M, Textor, Johannes, Figdor, Carl G, Piet, Berber, Theelen, Willemijn S M E, de Vries, I Jolanda M
Publicado 2022

Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer

por Westdorp, Harm, Creemers, Jeroen H. A., van Oort, Inge M., Schreibelt, Gerty, Gorris, Mark A. J., Mehra, Niven, Simons, Michiel, de Goede, Anna L., van Rossum, Michelle M., Croockewit, Alexandra J., Figdor, Carl G., Witjes, J. Alfred, Aarntzen, Erik H. J. G., Mus, Roel D. M., Brüning, Mareke, Petry, Katja, Gotthardt, Martin, Barentsz, Jelle O., de Vries, I. Jolanda M., Gerritsen, Winald R.
Publicado 2019