Platelets of mice heterozygous for neurobeachin, a candidate gene for autism spectrum disorder, display protein changes related to aberrant protein kinase A activity

por Nuytens, Kim, Tuand, Krizia, Di Michele, Michela, Boonen, Kurt, Waelkens, Etienne, Freson, Kathleen, Creemers, John WM
Publicado 2013

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice

por Coppola, Ilaria, Brouwers, Bas, Walker, Leanne, Alar, Ceyhun, Meulemans, Sandra, White, Anne, Ramos-Molina, Bruno, Creemers, John W.M.
Publicado 2022

Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism

por Löffler, Dennis, Behrendt, Susanne, Creemers, John W.M., Klammt, Jürgen, Aust, Gabriela, Stanik, Juraj, Kiess, Wieland, Kovacs, Peter, Körner, Antje
Publicado 2016

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance

por Liang, Zhanfeng, Zhang, Zhaoqi, Zhang, Qian, Dong, Xue, Yang, Xiaofeng, Zhang, Jiayu, Lei, Tong, Creemers, John W.M., Zhang, Baojun, Zhao, Yong
Publicado 2022

Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity

por Creemers, John W.M., Choquet, Hélène, Stijnen, Pieter, Vatin, Vincent, Pigeyre, Marie, Beckers, Sigri, Meulemans, Sandra, Than, Manuel E., Yengo, Loïc, Tauber, Maithé, Balkau, Beverley, Elliott, Paul, Jarvelin, Marjo-Riitta, Van Hul, Wim, Van Gaal, Luc, Horber, Fritz, Pattou, François, Froguel, Philippe, Meyre, David
Publicado 2012

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

por Rosier, Karen, McDevitt, Molly T., Smet, Joél, Floyd, Brendan J., Verschoore, Maxime, Marcaida, Maria J., Bingman, Craig A., Lemmens, Irma, Dal Peraro, Matteo, Tavernier, Jan, Cravatt, Benjamin F., Gounko, Natalia V., Vints, Katlijn, Monnens, Yenthe, Bhalla, Kritika, Aerts, Laetitia, Rashan, Edrees H., Vanlander, Arnaud V., Van Coster, Rudy, Régal, Luc, Pagliarini, David J., Creemers, John W.M.
Publicado 2021