Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy

por Firdessa-Fite, Rebuma, Creusot, Rémi J.
Publicado 2019

Altered Function of Antigen-Presenting Cells in Type 1 Diabetes: A Challenge for Antigen-Specific Immunotherapy?

por Creusot, Rémi J., Postigo-Fernandez, Jorge, Teteloshvili, Nato
Publicado 2018

Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes

por Postigo-Fernandez, Jorge, Firdessa-Fite, Rebuma, Creusot, Rémi J.
Publicado 2022

Concise Review: Cell‐Based Therapies and Other Non‐Traditional Approaches for Type 1 Diabetes

por Creusot, Remi J., Battaglia, Manuela, Roncarolo, Maria‐Grazia, Fathman, C. Garrison
Publicado 2016

Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations

por Donocoff, Rachel S., Teteloshvili, Nato, Chung, Hyunsoo, Shoulson, Rivka, Creusot, Remi J.
Publicado 2020

Epitope-based precision immunotherapy of Type 1 diabetes

por Firdessa Fite, Rebuma, Bechi Genzano, Camillo, Mallone, Roberto, Creusot, Remi J.
Publicado 2023

It’s Time to Bring Dendritic Cell Therapy to Type 1 Diabetes

por Creusot, Rémi J., Giannoukakis, Nick, Trucco, Massimo, Clare-Salzler, Michael J., Fathman, C. Garrison
Publicado 2014

Rapid video-based deep learning of cognate versus non-cognate T cell-dendritic cell interactions

por Anandakumaran, Priya N., Ayers, Abigail G., Muranski, Pawel, Creusot, Remi J., Sia, Samuel K.
Publicado 2022

Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8(+) T Cells

por Li, Yang, Teteloshvili, Nato, Tan, Shulian, Rao, Samhita, Han, Arnold, Yang, Yong-Guang, Creusot, Rémi J.
Publicado 2019

Soluble antigen arrays improve the efficacy and safety of peptide-based tolerogenic immunotherapy

por Firdessa-Fite, Rebuma, Johnson, Stephanie N., Leon, Martin A., Sestak, Joshua O., Berkland, Cory, Creusot, Remi J.
Publicado 2023

Efficient Presentation of Multiple Endogenous Epitopes to Both CD4(+) and CD8(+) Diabetogenic T Cells for Tolerance

por Dastagir, Shamael R., Postigo-Fernandez, Jorge, Xu, Chunliang, Stoeckle, James H., Firdessa-Fite, Rebuma, Creusot, Rémi J.
Publicado 2016

Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes

por Firdessa-Fite, Rebuma, Johnson, Stephanie N., Leon, Martin A., Khosravi-Maharlooei, Mohsen, Baker, Rocky L., Sestak, Joshua O., Berkland, Cory, Creusot, Remi J.
Publicado 2021

Negative selection of human T cells recognizing a naturally-expressed tissue-restricted antigen in the human thymus

por Madley, Rachel, Nauman, Grace, Danzl, Nichole, Borsotti, Chiara, Khosravi Maharlooei, Mohsen, Li, Hao Wei, Chavez, Estefania, Creusot, Remi J., Nakayama, Maki, Roep, Bart, Sykes, Megan
Publicado 2020

Inflammation and Hyperglycemia Mediate Deaf1 Splicing in the Pancreatic Lymph Nodes via Distinct Pathways During Type 1 Diabetes

por Yip, Linda, Fuhlbrigge, Rebecca, Taylor, Cariel, Creusot, Remi J., Nishikawa-Matsumura, Teppei, Whiting, Chan C., Schartner, Jill M., Akter, Rahima, von Herrath, Matthias, Fathman, C. Garrison
Publicado 2015

Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity

por Foo, Kylie S., Skowronski, Alicja A., Baum, Danielle, Firdessa-Fite, Rebuma, Thams, Sebastian, Shang, Linshan, Creusot, Rémi J., LeDuc, Charles A., Egli, Dieter, Leibel, Rudolph L.
Publicado 2019

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

por Yip, Linda, Su, Leon, Sheng, Deqiao, Chang, Pearl, Atkinson, Mark, Czesak, Margaret, Albert, Paul R., Collier, Ai-Ris, Turley, Shannon J., Fathman, C. Garrison, Creusot, Rémi J.
Publicado 2009

Modeling human T1D-associated autoimmune processes

por Khosravi-Maharlooei, Mohsen, Madley, Rachel, Borsotti, Chiara, Ferreira, Leonardo M.R., Sharp, Robert C., Brehm, Michael A., Greiner, Dale L., Parent, Audrey V., Anderson, Mark S., Sykes, Megan, Creusot, Remi J.
Publicado 2021

Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis

por Kang, Jinku, Postigo-Fernandez, Jorge, Kim, KyeongJin, Zhu, Changyu, Yu, Junjie, Meroni, Marica, Mayfield, Brent, Bartolomé, Alberto, Dapito, Dianne H., Ferrante, Anthony W., Dongiovanni, Paola, Valenti, Luca, Creusot, Remi J., Pajvani, Utpal B.
Publicado 2023

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines

por Junttila, Ilkka S., Creusot, Remi J., Moraga, Ignacio, Bates, Darren L., Wong, Michael T., Alonso, Michael N., Suhoski, Megan M., Lupardus, Patrick, Meier-Schellersheim, Martin, Engleman, Edgar G., Utz, Paul J., Fathman, C. Garrison, Paul, William E., Garcia, K. Christopher
Publicado 2012

Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals

por Du, Wen, Wang, Junqiang, Kuo, Taiyi, Wang, Liheng, McKimpson, Wendy M., Son, Jinsook, Watanabe, Hitoshi, Kitamoto, Takumi, Lee, Yunkyoung, Creusot, Remi J., Ratner, Lloyd E., McCune, Kasi, Chen, Ya-Wen, Grubbs, Brendan H., Thornton, Matthew E., Fan, Jason, Sultana, Nishat, Diaz, Bryan S., Balasubramanian, Iyshwarya, Gao, Nan, Belvedere, Sandro, Accili, Domenico
Publicado 2022