TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism

por Chernov-Rogan, Tania, Gianti, Eleonora, Liu, Chang, Villemure, Elisia, Cridland, Andrew P., Hu, Xiaoyu, Ballini, Elisa, Lange, Wienke, Deisemann, Heike, Li, Tianbo, Ward, Stuart I., Hackos, David H., Magnuson, Steven, Safina, Brian, Klein, Michael L., Volgraf, Matthew, Carnevale, Vincenzo, Chen, Jun
Publicado 2019

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

por Everett, Martin J., Davies, David T., Leiris, Simon, Sprynski, Nicolas, Llanos, Agustina, Castandet, Jérôme M., Lozano, Clarisse, LaRock, Christopher N., LaRock, Doris L., Corsica, Giuseppina, Docquier, Jean-Denis, Pallin, Thomas D., Cridland, Andrew, Blench, Toby, Zalacain, Magdalena, Lemonnier, Marc
Publicado 2023