Heterogeneity of the cancer cell line metabolic landscape

por Shorthouse, David, Bradley, Jenna, Critchlow, Susan E, Bendtsen, Claus, Hall, Benjamin A
Publicado 2022

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

por Mehibel, Manal, Ortiz-Martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-Klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.
Publicado 2018

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity

por Curtis, Nicola J., Mooney, Lorraine, Hopcroft, Lorna, Michopoulos, Filippos, Whalley, Nichola, Zhong, Haihong, Murray, Clare, Logie, Armelle, Revill, Mitchell, Byth, Kate F., Benjamin, Amanda D., Firth, Mike A., Green, Stephen, Smith, Paul D., Critchlow, Susan E.
Publicado 2017

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

por Noble, Richard A., Bell, Natalie, Blair, Helen, Sikka, Arti, Thomas, Huw, Phillips, Nicole, Nakjang, Sirintra, Miwa, Satomi, Crossland, Rachel, Rand, Vikki, Televantou, Despina, Long, Anna, Keun, Hector C., Bacon, Chris M., Bomken, Simon, Critchlow, Susan E., Wedge, Stephen R.
Publicado 2017

Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper

por Illuzzi, Giuditta, Staniszewska, Anna D., Gill, Sonja J., Pike, Andy, McWilliams, Lisa, Critchlow, Susan E., Cronin, Anna, Fawell, Stephen, Hawthorne, Glen, Jamal, Kunzah, Johannes, Jeffrey, Leonard, Emilyanne, Macdonald, Ruth, Maglennon, Gareth, Nikkilä, Jenni, O'Connor, Mark J., Smith, Aaron, Southgate, Harriet, Wilson, Joanne, Yates, James, Cosulich, Sabina, Leo, Elisabetta
Publicado 2022

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

por Peck, Barrie, Schug, Zachary T., Zhang, Qifeng, Dankworth, Beatrice, Jones, Dylan T., Smethurst, Elizabeth, Patel, Rachana, Mason, Susan, Jiang, Ming, Saunders, Rebecca, Howell, Michael, Mitter, Richard, Spencer-Dene, Bradley, Stamp, Gordon, McGarry, Lynn, James, Daniel, Shanks, Emma, Aboagye, Eric O., Critchlow, Susan E., Leung, Hing Y., Harris, Adrian L., Wakelam, Michael J. O., Gottlieb, Eyal, Schulze, Almut
Publicado 2016

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

por Schug, Zachary T., Peck, Barrie, Jones, Dylan T., Zhang, Qifeng, Grosskurth, Shaun, Alam, Israt S., Goodwin, Louise M., Smethurst, Elizabeth, Mason, Susan, Blyth, Karen, McGarry, Lynn, James, Daniel, Shanks, Emma, Kalna, Gabriela, Saunders, Rebecca E., Jiang, Ming, Howell, Michael, Lassailly, Francois, Thin, May Zaw, Spencer-Dene, Bradley, Stamp, Gordon, van den Broek, Niels J.F., Mackay, Gillian, Bulusu, Vinay, Kamphorst, Jurre J., Tardito, Saverio, Strachan, David, Harris, Adrian L., Aboagye, Eric O., Critchlow, Susan E., Wakelam, Michael J.O., Schulze, Almut, Gottlieb, Eyal
Publicado 2015

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER(+) Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance

por Lawson, Mandy, Cureton, Natalie, Ros, Susana, Cheraghchi-Bashi, Azadeh, Urosevic, Jelena, D'Arcy, Sophie, Delpuech, Oona, DuPont, Michelle, Fisher, David I., Gangl, Eric T., Lewis, Hilary, Trueman, Dawn, Wali, Neha, Williamson, Stuart C., Moss, Jennifer, Montaudon, Elodie, Derrien, Heloise, Marangoni, Elisabetta, Miragaia, Ricardo J., Gagrica, Sladjana, Morentin-Gutierrez, Pablo, Moss, Thomas A., Maglennon, Gareth, Sutton, Daniel, Polanski, Radoslaw, Rosen, Alan, Cairns, Jonathan, Zhang, Pei, Sánchez-Guixé, Mònica, Serra, Violeta, Critchlow, Susan E., Scott, James S., Lindemann, Justin P.O., Barry, Simon T., Klinowska, Teresa, Morrow, Christopher J., S Carnevalli, Larissa
Publicado 2023