An ontogenetic switch drives the positive and negative selection of B cells

por Xu, Xijin, Deobagkar-Lele, Mukta, Bull, Katherine R., Crockford, Tanya L., Mead, Adam J., Cribbs, Adam P., Sims, David, Anzilotti, Consuelo, Cornall, Richard J.
Publicado 2020

Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson’s syndrome

por Bull, Katherine R, Mason, Thomas, Rimmer, Andrew J, Crockford, Tanya L, Silver, Karlee L, Bouriez-Jones, Tiphaine, Hough, Tertius A, Chaudhry, Shirine, Roberts, Ian SD, Goodnow, Christopher C, Cornall, Richard J
Publicado 2013

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance

por Hodgson, Rose, Xu, Xijin, Anzilotti, Consuelo, Deobagkar-Lele, Mukta, Crockford, Tanya L., Kepple, Jessica D., Cawthorne, Eleanor, Bhandari, Aneesha, Cebrian-Serrano, Alberto, Wilcock, Martin J., Davies, Benjamin, Cornall, Richard J., Bull, Katherine R.
Publicado 2022

Themis is a member of a new metazoan gene family and is required for completion of thymocyte positive selection

por Johnson, Andy L., Aravind, L., Shulzhenko, Natalia, Morgun, Andriy, Choi, See-Young, Crockford, Tanya L., Lambe, Teresa, Domaschenz, Heather, Kucharska, Edyta, Zheng, Lixin, Vinuesa, Carola C., Lenardo, Michael J., Goodnow, Christopher C., Cornall, Richard J., Schwartz, Ronald H.
Publicado 2009

Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity

por Hodgson, Rose, Crockford, Tanya L., Bhandari, Aneesha, Kepple, Jessica D., Back, Jennifer, Cawthorne, Eleanor, Abeler-Dörner, Lucie, Laing, Adam G., Clare, Simon, Speak, Anneliese, Adams, David J., Dougan, Gordon, Hayday, Adrian C., Deobagkar-Lele, Mukta, Cornall, Richard J., Bull, Katherine R.
Publicado 2023

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

por Heazlewood, Chad K, Cook, Matthew C, Eri, Rajaraman, Price, Gareth R, Tauro, Sharyn B, Taupin, Douglas, Thornton, David J, Png, Chin Wen, Crockford, Tanya L, Cornall, Richard J, Adams, Rachel, Kato, Masato, Nelms, Keats A, Hong, Nancy A, Florin, Timothy H. J, Goodnow, Christopher C, McGuckin, Michael A
Publicado 2008

Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations

por Bull, Katherine R., Rimmer, Andrew J., Siggs, Owen M., Miosge, Lisa A., Roots, Carla M., Enders, Anselm, Bertram, Edward M., Crockford, Tanya L., Whittle, Belinda, Potter, Paul K., Simon, Michelle M., Mallon, Ann-Marie, Brown, Steve D. M., Beutler, Bruce, Goodnow, Christopher C., Lunter, Gerton, Cornall, Richard J.
Publicado 2013

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

por Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Publicado 2019