Unlocking the potential of in silico chemical safety assessment – A report on a cross-sector symposium on current opportunities and future challenges

por Cronin, Mark T.D., Madden, Judith C., Yang, Chihae, Worth, Andrew P.
Publicado 2019

A matter of trust: Learning lessons about causality will make qAOPs credible

por Spînu, Nicoleta, Cronin, Mark T.D., Madden, Judith C., Worth, Andrew P.
Publicado 2022

Guidance for good practice in the application of machine learning in development of toxicological quantitative structure-activity relationships (QSARs)

por Belfield, Samuel J., Cronin, Mark T.D., Enoch, Steven J., Firman, James W.
Publicado 2023

In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects

por Cronin, Mark T.D., Enoch, Steven J., Mellor, Claire L., Przybylak, Katarzyna R., Richarz, Andrea-Nicole, Madden, Judith C.
Publicado 2017

Automated workflows for modelling chemical fate, kinetics and toxicity

por Sala Benito, J.V., Paini, Alicia, Richarz, Andrea-Nicole, Meinl, Thorsten, Berthold, Michael R., Cronin, Mark T.D., Worth, Andrew P.
Publicado 2017

Quantifying intrinsic chemical reactivity of molecular structural features for protein binding and reactive toxicity, using the MOSES chemoinformatics system

por Schwöbel, Johannes AH, Bienfait, Bruno, Gasteiger, Johann, Kleinöder, Thomas, Marusczyk, Jörg, Sacher, Oliver, Schwab, Christof H, Tarkhov, Aleksey, Terfloth, Lothar, Cronin, Mark TD
Publicado 2012

A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties

por Cronin, Mark T.D., Bauer, Franklin J., Bonnell, Mark, Campos, Bruno, Ebbrell, David J., Firman, James W., Gutsell, Steve, Hodges, Geoff, Patlewicz, Grace, Sapounidou, Maria, Spînu, Nicoleta, Thomas, Paul C., Worth, Andrew P.
Publicado 2022

Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network

por Spînu, Nicoleta, Cronin, Mark T.D., Lao, Junpeng, Bal-Price, Anna, Campia, Ivana, Enoch, Steven J., Madden, Judith C., Mora Lagares, Liadys, Novič, Marjana, Pamies, David, Scholz, Stefan, Villeneuve, Daniel L., Worth, Andrew P.
Publicado 2022

Towards a qAOP framework for predictive toxicology - Linking data to decisions

por Paini, Alicia, Campia, Ivana, Cronin, Mark T.D., Asturiol, David, Ceriani, Lidia, Exner, Thomas E., Gao, Wang, Gomes, Caroline, Kruisselbrink, Johannes, Martens, Marvin, Meek, M.E. Bette, Pamies, David, Pletz, Julia, Scholz, Stefan, Schüttler, Andreas, Spînu, Nicoleta, Villeneuve, Daniel L., Wittwehr, Clemens, Worth, Andrew, Luijten, Mirjam
Publicado 2022

Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

por Drakvik, Elina, Altenburger, Rolf, Aoki, Yasunobu, Backhaus, Thomas, Bahadori, Tina, Barouki, Robert, Brack, Werner, Cronin, Mark T.D., Demeneix, Barbara, Bennekou, Susanne Hougaard, van Klaveren, Jacob, Kneuer, Carsten, Kolossa-Gehring, Marike, Lebret, Erik, Posthuma, Leo, Reiber, Lena, Rider, Cynthia, Rüegg, Joëlle, Testa, Giuseppe, van der Burg, Bart, van der Voet, Hilko, Warhurst, A. Michael, van de Water, Bob, Yamazaki, Kunihiko, Öberg, Mattias, Bergman, Åke
Publicado 2019