Antisense technology: A review

por Crooke, Stanley T., Liang, Xue-Hai, Baker, Brenda F., Crooke, Rosanne M.
Publicado 2021

Antisense Technology: An Emerging Platform for Cardiovascular Disease Therapeutics

por Lee, Richard G., Crosby, Jeff, Baker, Brenda F., Graham, Mark J., Crooke, Rosanne M.
Publicado 2013

Evaluation of an Anti-Tumor Necrosis Factor Therapeutic in a Mouse Model of Niemann-Pick C Liver Disease

por Vincent, Melanie, Sayre, Naomi L., Graham, Mark J., Crooke, Rosanne M., Shealy, David J., Liscum, Laura
Publicado 2010

CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation

por Donner, Aaron J, Yeh, Steve T, Hung, Gene, Graham, Mark J, Crooke, Rosanne M, Mullick, Adam E
Publicado 2015

Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

por Bell, Thomas A., Liu, Mingxia, Donner, Aaron J., Lee, Richard G., Mullick, Adam E., Crooke, Rosanne M.
Publicado 2021

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr(−/−) mice

por Bell, Thomas A., Graham, Mark J., Lee, Richard G., Mullick, Adam E., Fu, Wuxia, Norris, Dan, Crooke, Rosanne M.
Publicado 2013

Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

por Wu, Chia-Hua, Wang, Ya, Ma, Murong, Mullick, Adam E., Crooke, Rosanne M., Graham, Mark J., Daugherty, Alan, Lu, Hong S.
Publicado 2019

Effects of an Antisense Oligonucleotide Inhibitor of C‐Reactive Protein Synthesis on the Endotoxin Challenge Response in Healthy Human Male Volunteers

por Noveck, Robert, Stroes, Erik S. G., Flaim, JoAnn D., Baker, Brenda F., Hughes, Steve, Graham, Mark J., Crooke, Rosanne M., Ridker, Paul M
Publicado 2014

Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits

por Yu, Qi, Liu, Zhengcao, Waqar, Ahmed Bilal, Ning, Bo, Yang, Xianghong, Shiomi, Masashi, Graham, Mark J., Crooke, Rosanne M., Liu, Enqi, Dong, Sijun, Fan, Jianglin
Publicado 2014

Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels

por Liang, Xue-hai, Sun, Hong, Shen, Wen, Wang, Shiyu, Yao, Joyee, Migawa, Michael T., Bui, Huynh-Hoa, Damle, Sagar S., Riney, Stan, Graham, Mark J., Crooke, Rosanne M., Crooke, Stanley T.
Publicado 2017

A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans

por Jones, Nicholas R, Pegues, Melissa A, McCrory, Mark A, Singleton, Walter, Bethune, Claudette, Baker, Brenda F, Norris, Daniel A, Crooke, Rosanne M, Graham, Mark J, Szalai, Alexander J
Publicado 2012

Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering

por Ramms, Bastian, Patel, Sohan, Sun, Xiaoli, Pessentheiner, Ariane R., Ducasa, G. Michelle, Mullick, Adam E., Lee, Richard G., Crooke, Rosanne M., Tsimikas, Sotirios, Witztum, Joseph L., Gordts, Philip L.S.M.
Publicado 2022

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

por Miao, Ji, Ling, Alisha V., Manthena, Praveen V., Gearing, Mary E., Graham, Mark J., Crooke, Rosanne M., Croce, Kevin J., Esquejo, Ryan M., Clish, Clary B., Vicent, David, Biddinger, Sudha B.
Publicado 2015

Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained...

por Pirie, Elaine, Ray, Shayoni, Pan, Calvin, Fu, Wuxia, Powers, Andrew F., Polikoff, Danielle, Miller, Colton M., Kudrna, Katrina M., Harris, Edward N., Lusis, Aldons J., Crooke, Rosanne M., Lee, Richard G.
Publicado 2018

Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion

por Marshall, Stephanie M., Gromovsky, Anthony D., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Rudel, Lawrence L., Brown, J. Mark, Temel, Ryan E.
Publicado 2014

Reduction of VLDL Secretion Decreases Cholesterol Excretion in Niemann-Pick C1-Like 1 Hepatic Transgenic Mice

por Marshall, Stephanie M., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., McDaniel, Allison L., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Rudel, Lawrence L., Brown, J. Mark, Temel, Ryan E.
Publicado 2014

Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models

por Szalai, Alexander J., McCrory, Mark A., Xing, Dongqi, Hage, Fadi G., Miller, Andrew, Oparil, Suzanne, Chen, Yiu-Fai, Mazzone, Michelle, Early, Richard, Henry, Scott P., Zanardi, Thomas A., Graham, Mark J., Crooke, Rosanne M.
Publicado 2014

CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

por Lord, Caleb C., Betters, Jenna L., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Madenspacher, Jennifer, Thomas, Gwynneth, Chung, Soonkyu, Liu, Mingxia, Davis, Matthew A., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Parks, John S., Brasaemle, Dawn L., Fessler, Michael B., Brown, H. Alex, Brown, J. Mark
Publicado 2012

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

por Helsley, Robert N, Varadharajan, Venkateshwari, Brown, Amanda L, Gromovsky, Anthony D, Schugar, Rebecca C, Ramachandiran, Iyappan, Fung, Kevin, Kabbany, Mohammad Nasser, Banerjee, Rakhee, Neumann, Chase K, Finney, Chelsea, Pathak, Preeti, Orabi, Danny, Osborn, Lucas J, Massey, William, Zhang, Renliang, Kadam, Anagha, Sansbury, Brian E, Pan, Calvin, Sacks, Jessica, Lee, Richard G, Crooke, Rosanne M, Graham, Mark J, Lemieux, Madeleine E, Gogonea, Valentin, Kirwan, John P, Allende, Daniela S, Civelek, Mete, Fox, Paul L, Rudel, Lawrence L, Lusis, Aldons J, Spite, Matthew, Brown, J Mark
Publicado 2019