Rapid optimization of processes for the integrated purification of biopharmaceuticals

por Crowell, Laura E., Rodriguez, Sergio A., Love, Kerry R., Cramer, Steven M., Love, J. Christopher
Publicado 2021

Comparative analysis of the end-joining activity of several DNA ligases

por Bauer, Robert J., Zhelkovsky, Alexander, Bilotti, Katharina, Crowell, Laura E., Evans, Thomas C., McReynolds, Larry A., Lohman, Gregory J. S.
Publicado 2017

Large-Scale Purification and Characterization of Recombinant Receptor-Binding Domain (RBD) of SARS-CoV-2 Spike Protein Expressed in Yeast

por Nagar, Gaurav, Jain, Siddharth, Rajurkar, Meghraj, Lothe, Rakesh, Rao, Harish, Majumdar, Sourav, Gautam, Manish, Rodriguez-Aponte, Sergio A., Crowell, Laura E., Love, J. Christopher, Dandekar, Prajakta, Puranik, Amita, Gairola, Sunil, Shaligram, Umesh, Jain, Ratnesh
Publicado 2023

Development of a platform process for the production and purification of single‐domain antibodies

por Crowell, Laura E., Goodwine, Chaz, Holt, Carla S., Rocha, Lucia, Vega, Celina, Rodriguez, Sergio A., Dalvie, Neil C., Tracey, Mary K., Puntel, Mariana, Wigdorovitz, Andrés, Parreño, Viviana, Love, Kerry R., Cramer, Steven M., Love, J. Christopher
Publicado 2021

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii

por Dalvie, Neil C., Biedermann, Andrew M., Rodriguez-Aponte, Sergio A., Naranjo, Christopher A., Rao, Harish D., Rajurkar, Meghraj P., Lothe, Rakesh R., Shaligram, Umesh S., Johnston, Ryan S., Crowell, Laura E., Castelino, Seraphin, Tracey, Mary Kate, Whittaker, Charles A., Love, J. Christopher
Publicado 2021

Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii

por Dalvie, Neil C., Biedermann, Andrew M., Rodriguez‐Aponte, Sergio A., Naranjo, Christopher A., Rao, Harish D., Rajurkar, Meghraj P., Lothe, Rakesh R., Shaligram, Umesh S., Johnston, Ryan S., Crowell, Laura E., Castelino, Seraphin, Tracey, Mary K., Whittaker, Charles A., Love, J. Christopher
Publicado 2021

Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

por Dalvie, Neil C., Brady, Joseph R., Crowell, Laura E., Tracey, Mary Kate, Biedermann, Andrew M., Kaur, Kawaljit, Hickey, John M., Kristensen, D. Lee, Bonnyman, Alexandra D., Rodriguez-Aponte, Sergio A., Whittaker, Charles A., Bok, Marina, Vega, Celina, Mukhopadhyay, Tarit K., Joshi, Sangeeta B., Volkin, David B., Parreño, Viviana, Love, Kerry R., Love, J. Christopher
Publicado 2021

On-demand manufacturing of clinical-quality biopharmaceuticals

por Crowell, Laura E., Lu, Amos E., Love, Kerry R., Stockdale, Alan, Timmick, Steven M., Wu, Di, Wang, Yu (Annie), Doherty, William, Bonnyman, Alexandra, Vecchiarello, Nicholas, Goodwine, Chaz, Bradbury, Lisa, Brady, Joseph R., Clark, John J., Colant, Noelle A., Cvetkovic, Aleksandar, Dalvie, Neil C., Liu, Diana, Liu, Yanjun, Mascarenhas, Craig A., Matthews, Catherine B., Mozdzierz, Nicholas J., Shah, Kartik A., Wu, Shiaw-Lin, Hancock, William S., Braatz, Richard D., Cramer, Steven M., Love, J. Christopher
Publicado 2018

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan, Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan S., Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Brunette, Natalie, Wang, Jing Yang, Walkey, Carl, Fiala, Brooke, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021