Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease

por Li, Sienna R., Gulieva, Ramila E., Helms, Louisa, Cruz, Nelly M., Vincent, Thomas, Fu, Hongxia, Himmelfarb, Jonathan, Freedman, Benjamin S.
Publicado 2022

Modifier Genes as Therapeutics: The Nuclear Hormone Receptor Rev Erb Alpha (Nr1d1) Rescues Nr2e3 Associated Retinal Disease

por Cruz, Nelly M., Yuan, Yang, Leehy, Barrett D., Baid, Rinku, Kompella, Uday, DeAngelis, Margaret M., Escher, Pascal, Haider, Neena B.
Publicado 2014

Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis

por Gopalan, Janani, Omar, Mitchell H, Roy, Ankita, Cruz, Nelly M, Falcone, Jerome, Jones, Kiana N, Forbush, Katherine A, Himmelfarb, Jonathan, Freedman, Benjamin S, Scott, John D
Publicado 2021

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease

por Cruz, Nelly M., Song, Xuewen, Czerniecki, Stefan M., Gulieva, Ramila E., Churchill, Angela J., Kim, Yong Kyun, Winston, Kosuke, Tran, Linh M., Diaz, Marco A., Fu, Hongxia, Finn, Laura S., Pei, York, Himmelfarb, Jonathan, Freedman, Benjamin S.
Publicado 2017

Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma

por Suresh, Shruthy, Rabbie, Roy, Garg, Manik, Lumaquin, Dianne, Huang, Ting-Hsiang, Montal, Emily, Ma, Yilun, Cruz, Nelly M, Tang, Xinran, Nsengimana, Jérémie, Newton-Bishop, Julia, Hunter, Miranda V., Zhu, Yuxin, Chen, Kevin, de Stanchina, Elisa, Adams, David J., White, Richard M.
Publicado 2023

GABA Regulates Electrical Activity and Tumor Initiation in Melanoma

por Tagore, Mohita, Hergenreder, Emiliano, Perlee, Sarah C., Cruz, Nelly M., Menocal, Laura, Suresh, Shruthy, Chan, Eric, Baron, Maayan, Melendez, Stephanie, Dave, Asim, Chatila, Walid K., Nsengimana, Jeremie, Koche, Richard P., Hollmann, Travis J., Ideker, Trey, Studer, Lorenz, Schietinger, Andrea, White, Richard M.
Publicado 2023