Transcription Factor Nrf2: a novel target to modulate inflammatory and neuroprotective responses in Parkinson’s disease

por Cuadrado, Antonio
Publicado 2015

Mechanisms of NURR1 Regulation: Consequences for Its Biological Activity and Involvement in Pathology

por García-Yagüe, Ángel Juan, Cuadrado, Antonio
Publicado 2023

Transcription Factor NRF2 Participates in Cell Cycle Progression at the Level of G1/S and Mitotic Checkpoints

por Lastra, Diego, Escoll, Maribel, Cuadrado, Antonio
Publicado 2022

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

por Pajares, Marta, Cuadrado, Antonio, Rojo, Ana I.
Publicado 2017

Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

por Cuadrado, Antonio, Kügler, Sebastian, Lastres-Becker, Isabel
Publicado 2017

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

por Robledinos-Antón, Natalia, Fernández-Ginés, Raquel, Manda, Gina, Cuadrado, Antonio
Publicado 2019

TAZ Represses the Neuronal Commitment of Neural Stem Cells

por Robledinos-Antón, Natalia, Escoll, Maribel, Guan, Kun-Liang, Cuadrado, Antonio
Publicado 2020

Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson’s Disease

por Duarte, Pablo, Michalska, Patrycja, Crisman, Enrique, Cuadrado, Antonio, León, Rafael
Publicado 2022

Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

por Bourdakou, Marilena M., Fernández-Ginés, Raquel, Cuadrado, Antonio, Spyrou, George M.
Publicado 2023

Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications

por Pajares, Marta, I. Rojo, Ana, Manda, Gina, Boscá, Lisardo, Cuadrado, Antonio
Publicado 2020

NRF2 and Primary Cilia: An Emerging Partnership

por Martin-Hurtado, Ana, Lastres-Becker, Isabel, Cuadrado, Antonio, Garcia-Gonzalo, Francesc R.
Publicado 2020

Nordihydroguaiaretic Acid: From Herbal Medicine to Clinical Development for Cancer and Chronic Diseases

por Manda, Gina, Rojo, Ana I., Martínez-Klimova, Elena, Pedraza-Chaverri, José, Cuadrado, Antonio
Publicado 2020

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

por Chowdhry, Sudhir, Zhang, Yiguo, McMahon, Michael, Sutherland, Calum, Cuadrado, Antonio, Hayes, John D.
Publicado 2012

Effects of Nrf2 Deficiency on Bone Microarchitecture in an Experimental Model of Osteoporosis

por Ibáñez, Lidia, Ferrándiz, María Luisa, Brines, Rita, Guede, David, Cuadrado, Antonio, Alcaraz, Maria José
Publicado 2014

WIP Modulates Oxidative Stress through NRF2/KEAP1 in Glioblastoma Cells

por Escoll, Maribel, Lastra, Diego, Robledinos-Antón, Natalia, Wandosell, Francisco, Antón, Inés María, Cuadrado, Antonio
Publicado 2020

α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks

por García-Yagüe, Ángel Juan, Lastres-Becker, Isabel, Stefanis, Leonidas, Vassilatis, Demetrios K., Cuadrado, Antonio
Publicado 2021

Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer’s Disease, Common to APP(V717I) × TAU(P301L) Mice and Patients

por Cucos, Catalina Anca, Milanesi, Elena, Dobre, Maria, Musat, Ioana Andreea, Manda, Gina, Cuadrado, Antonio
Publicado 2022

Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A

por Pajares, Marta, Rojo, Ana I, Arias, Esperanza, Díaz-Carretero, Antonio, Cuervo, Ana María, Cuadrado, Antonio
Publicado 2018

Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets

por Bourgonje, Arno R., Kloska, Damian, Grochot-Przęczek, Anna, Feelisch, Martin, Cuadrado, Antonio, van Goor, Harry
Publicado 2023

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

por Crisman, Enrique, Duarte, Pablo, Dauden, Esteban, Cuadrado, Antonio, Rodríguez‐Franco, María Isabel, López, Manuela G., León, Rafael
Publicado 2022