Analysis of lysosomal hydrolase trafficking and activity in human iPSC-derived neuronal models

por Cuddy, Leah K., Mazzulli, Joseph R.
Publicado 2021

Amino-Terminal β-Amyloid Antibody Blocks β-Amyloid-Mediated Inhibition of the High-Affinity Choline Transporter CHT

por Cuddy, Leah K., Seah, Claudia, Pasternak, Stephen H., Rylett, R. Jane
Publicado 2017

Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models

por Alia, Alia O., Jeon, Sohee, Popovic, Jelena, Salvo, Miranda A., Sadleir, Katherine R., Vassar, Robert, Cuddy, Leah K.
Publicado 2022

The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms

por Chandra, Sidhanth, Di Meco, Antonio, Dodiya, Hemraj B., Popovic, Jelena, Cuddy, Leah K., Weigle, Ian Q., Zhang, Xiaoqiong, Sadleir, Katherine, Sisodia, Sangram S., Vassar, Robert
Publicado 2023

Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

por Cuddy, Leah K., Alia, Alia O., Salvo, Miranda A., Chandra, Sidhanth, Grammatopoulos, Tom N., Justman, Craig J., Lansbury, Peter T., Mazzulli, Joseph R., Vassar, Robert
Publicado 2022