Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?

por Cuello, Friederike, Lorenz, Kristina
Publicado 2016

Regulation by phosphodiesterase isoforms of protein kinase A-mediated attenuation of myocardial protein kinase D activation

por Haworth, Robert S., Cuello, Friederike, Avkiran, Metin
Publicado 2010

Regulation of Cardiac PKA Signaling by cAMP and Oxidants

por Cuello, Friederike, Herberg, Friedrich W., Stathopoulou, Konstantina, Henning, Philipp, Diering, Simon
Publicado 2021

Proteomics Analysis of the Cardiac Myofilament Subproteome Reveals Dynamic Alterations in Phosphatase Subunit Distribution

por Yin, Xiaoke, Cuello, Friederike, Mayr, Ursula, Hao, Zhiqi, Hornshaw, Martin, Ehler, Elisabeth, Avkiran, Metin, Mayr, Manuel
Publicado 2010

Four-and-a-half LIM domains proteins are novel regulators of the protein kinase D pathway in cardiac myocytes

por Stathopoulou, Konstantina, Cuello, Friederike, Candasamy, Alexandra J., Kemp, Elizabeth M., Ehler, Elisabeth, Haworth, Robert S., Avkiran, Metin
Publicado 2014

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

por Madhani, Melanie, Hall, Andrew R., Cuello, Friederike, Charles, Rebecca L., Burgoyne, Joseph R., Fuller, William, Hobbs, Adrian J., Shattock, Michael J., Eaton, Philip
Publicado 2010

A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia

por Burnap, Sean A., Mayr, Ursula, Shankar-Hari, Manu, Cuello, Friederike, Thomas, Mark R., Shah, Ajay M., Sabroe, Ian, Storey, Robert F., Mayr, Manuel
Publicado 2021

Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytes

por Candasamy, Alexandra J., Haworth, Robert S., Cuello, Friederike, Ibrahim, Michael, Aravamudhan, Sriram, Krüger, Marcus, Holt, Mark R., Terracciano, Cesare M. N., Mayr, Manuel, Gautel, Mathias, Avkiran, Metin
Publicado 2014

Increased myofilament Ca(2+) sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

por Fraysse, Bodvaël, Weinberger, Florian, Bardswell, Sonya C., Cuello, Friederike, Vignier, Nicolas, Geertz, Birgit, Starbatty, Jutta, Krämer, Elisabeth, Coirault, Catherine, Eschenhagen, Thomas, Kentish, Jonathan C., Avkiran, Metin, Carrier, Lucie
Publicado 2012

Redox State of Pentraxin 3 as a Novel Biomarker for Resolution of Inflammation and Survival in Sepsis

por Cuello, Friederike, Shankar-Hari, Manu, Mayr, Ursula, Yin, Xiaoke, Marshall, Melanie, Suna, Gonca, Willeit, Peter, Langley, Sarah R., Jayawardhana, Tamani, Zeller, Tanja, Terblanche, Marius, Shah, Ajay M., Mayr, Manuel
Publicado 2014

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue

por Jacob, Fabian, Yonis, Amina Y., Cuello, Friederike, Luther, Pradeep, Schulze, Thomas, Eder, Alexandra, Streichert, Thomas, Mannhardt, Ingra, Hirt, Marc N., Schaaf, Sebastian, Stenzig, Justus, Force, Thomas, Eschenhagen, Thomas, Hansen, Arne
Publicado 2016

Correction: Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue

por Jacob, Fabian, Yonis, Amina Y., Cuello, Friederike, Luther, Pradeep, Schulze, Thomas, Eder, Alexandra, Streichert, Thomas, Mannhardt, Ingra, Hirt, Marc N., Schaaf, Sebastian, Stenzig, Justus, Force, Thomas, Eschenhagen, Thomas, Hansen, Arne
Publicado 2018

Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

por Reed, Ella, Fellows, Adam, Lu, Ruifang, Rienks, Marieke, Schmidt, Lukas, Yin, Xiaoke, Duregotti, Elisa, Brandt, Mona, Krasemann, Susanne, Hartmann, Kristin, Barallobre-Barreiro, Javier, Addison, Owen, Cuello, Friederike, Hansen, Arne, Mayr, Manuel
Publicado 2022

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

por Rhoden, Alexandra, Friedrich, Felix W., Brandt, Theresa, Raabe, Janice, Schweizer, Michaela, Meisterknecht, Jana, Wittig, Ilka, Ulmer, Bärbel M., Klampe, Birgit, Uebeler, June, Piasecki, Angelika, Lorenz, Kristina, Eschenhagen, Thomas, Hansen, Arne, Cuello, Friederike
Publicado 2021

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation

por Schaefer, Andreas, Schneeberger, Yvonne, Schulz, Steven, Krasemann, Susanne, Werner, Tessa, Piasecki, Angelika, Höppner, Grit, Müller, Christian, Morhenn, Karoline, Lorenz, Kristina, Wieczorek, David, Schwoerer, Alexander P., Eschenhagen, Thomas, Ehmke, Heimo, Reichenspurner, Hermann, Stenzig, Justus, Cuello, Friederike
Publicado 2019

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response

por Scotcher, Jenna, Prysyazhna, Oleksandra, Boguslavskyi, Andrii, Kistamas, Kornel, Hadgraft, Natasha, Martin, Eva D., Worthington, Jenny, Rudyk, Olena, Rodriguez Cutillas, Pedro, Cuello, Friederike, Shattock, Michael J., Marber, Michael S., Conte, Maria R., Greenstein, Adam, Greensmith, David J., Venetucci, Luigi, Timms, John F., Eaton, Philip
Publicado 2016

Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity

por Donzelli, Sonia, Goetz, Mara, Schmidt, Kjestine, Wolters, Markus, Stathopoulou, Konstantina, Diering, Simon, Prysyazhna, Oleksandra, Polat, Volkan, Scotcher, Jenna, Dees, Christian, Subramanian, Hariharan, Butt, Elke, Kamynina, Alisa, Schobesberger, Sophie, King, S. Bruce, Nikolaev, Viacheslav O., de Wit, Cor, Leichert, Lars I., Feil, Robert, Eaton, Philip, Cuello, Friederike
Publicado 2017

Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism

por Loos, Malte, Klampe, Birgit, Schulze, Thomas, Yin, Xiaoke, Theofilatos, Konstantinos, Ulmer, Bärbel Maria, Schulz, Carl, Behrens, Charlotta S., van Bergen, Tessa Diana, Adami, Eleonora, Maatz, Henrike, Schweizer, Michaela, Brodesser, Susanne, Skryabin, Boris V., Rozhdestvensky, Timofey S., Bodbin, Sara, Stathopoulou, Konstantina, Christ, Torsten, Denning, Chris, Hübner, Norbert, Mayr, Manuel, Cuello, Friederike, Eschenhagen, Thomas, Hansen, Arne
Publicado 2023

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects

por Tomasovic, Angela, Brand, Theresa, Schanbacher, Constanze, Kramer, Sofia, Hümmert, Martin W., Godoy, Patricio, Schmidt-Heck, Wolfgang, Nordbeck, Peter, Ludwig, Jonas, Homann, Susanne, Wiegering, Armin, Shaykhutdinov, Timur, Kratz, Christoph, Knüchel, Ruth, Müller-Hermelink, Hans-Konrad, Rosenwald, Andreas, Frey, Norbert, Eichler, Jutta, Dobrev, Dobromir, El-Armouche, Ali, Hengstler, Jan G., Müller, Oliver J., Hinrichs, Karsten, Cuello, Friederike, Zernecke, Alma, Lorenz, Kristina
Publicado 2020

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

por Cuello, Friederike, Knaust, Anika E, Saleem, Umber, Loos, Malte, Raabe, Janice, Mosqueira, Diogo, Laufer, Sandra, Schweizer, Michaela, van der Kraak, Petra, Flenner, Frederik, Ulmer, Bärbel M, Braren, Ingke, Yin, Xiaoke, Theofilatos, Konstantinos, Ruiz‐Orera, Jorge, Patone, Giannino, Klampe, Birgit, Schulze, Thomas, Piasecki, Angelika, Pinto, Yigal, Vink, Aryan, Hübner, Norbert, Harding, Sian, Mayr, Manuel, Denning, Chris, Eschenhagen, Thomas, Hansen, Arne
Publicado 2021