Investigation of factors responsible for cell line cytoplasmic expression differences

por Finn, Jonathan D, Wong, Tabitha, Cullis, Pieter R
Publicado 2005

Advances in Lipid Nanoparticles for siRNA Delivery

por Tam, Yuen Yi C., Chen, Sam, Cullis, Pieter R.
Publicado 2013

Lipid Nanoparticles for Short Interfering RNA Delivery

por Leung, Alex K.K., Tam, Yuen Yi C., Cullis, Pieter R.
Publicado 2014

Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues

por Chander, Nisha, Basha, Genc, Yan Cheng, Miffy Hok, Witzigmann, Dominik, Cullis, Pieter R.
Publicado 2023

Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo

por Basha, Genc, Ordobadi, Mina, Scott, Wilder R, Cottle, Andrew, Liu, Yan, Wang, Haitang, Cullis, Pieter R
Publicado 2016

Lipid nanoparticle technology for therapeutic gene regulation in the liver

por Witzigmann, Dominik, Kulkarni, Jayesh A., Leung, Jerry, Chen, Sam, Cullis, Pieter R., van der Meel, Roy
Publicado 2020

Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes

por Neumann, Ursula H., Ho, Jessica S.S., Chen, Sam, Tam, Yuen Yi C., Cullis, Pieter R., Kieffer, Timothy J.
Publicado 2017

Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective

por Labouta, Hagar I., Langer, Robert, Cullis, Pieter R., Merkel, Olivia M., Prausnitz, Mark R., Gomaa, Yasmine, Nogueira, Sara S., Kumeria, Tushar
Publicado 2022

Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

por Meulewaeter, Sofie, Nuytten, Gust, Cheng, Miffy H.Y., De Smedt, Stefaan C., Cullis, Pieter R., De Beer, Thomas, Lentacker, Ine, Verbeke, Rein
Publicado 2023

Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain

por Rungta, Ravi L, Choi, Hyun B, Lin, Paulo JC, Ko, Rebecca WY, Ashby, Donovan, Nair, Jay, Manoharan, Muthiah, Cullis, Pieter R, MacVicar, Brian A
Publicado 2013

Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use

por Chen, Kent T. J., Anantha, Malathi, Leung, Ada W. Y., Kulkarni, Jayesh A., Militao, Gardenia G. C., Wehbe, Mohamed, Sutherland, Brent, Cullis, Pieter R., Bally, Marcel B.
Publicado 2019

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

por Leung, Alex K. K., Hafez, Ismail M., Baoukina, Svetlana, Belliveau, Nathan M., Zhigaltsev, Igor V., Afshinmanesh, Elham, Tieleman, D. Peter, Hansen, Carl L., Hope, Michael J., Cullis, Pieter R.
Publicado 2012

Correction to “Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core”

por Leung, Alex K. K., Hafez, Ismail M., Baoukina, Svetlana, Belliveau, Nathan M., Zhigaltsev, Igor V., Afshinmanesh, Elham, Tieleman, D. Peter, Hansen, Carl L., Hope, Michael J., Cullis, Pieter R.
Publicado 2012

Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System

por Pattipeiluhu, Roy, Arias-Alpizar, Gabriela, Basha, Genc, Chan, Karen Y. T., Bussmann, Jeroen, Sharp, Thomas H., Moradi, Mohammad-Amin, Sommerdijk, Nico, Harris, Edward N., Cullis, Pieter R., Kros, Alexander, Witzigmann, Dominik, Campbell, Frederick
Publicado 2022

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

por Belliveau, Nathan M, Huft, Jens, Lin, Paulo JC, Chen, Sam, Leung, Alex KK, Leaver, Timothy J, Wild, Andre W, Lee, Justin B, Taylor, Robert J, Tam, Ying K, Hansen, Carl L, Cullis, Pieter R
Publicado 2012

Genetically engineered transfusable platelets using mRNA lipid nanoparticles

por Leung, Jerry, Strong, Colton, Badior, Katherine E., Robertson, Madelaine, Wu, Xiaowu, Meledeo, Michael A., Kang, Emma, Paul, Manoj, Sato, Yusuke, Harashima, Hideyoshi, Cap, Andrew P., Devine, Dana V., Jan, Eric, Cullis, Pieter R., Kastrup, Christian J.
Publicado 2023

A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo

por Lee, Justin B, Zhang, Kaixin, Tam, Yuen Yi C, Quick, Joslyn, Tam, Ying K, Lin, Paulo JC, Chen, Sam, Liu, Yan, Nair, Jayaprakash K, Zlatev, Ivan, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Rennie, Paul S, Cullis, Pieter R
Publicado 2016

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells

por Basha, Genc, Novobrantseva, Tatiana I, Rosin, Nicole, Tam, Yuen Yi C, Hafez, Ismail M, Wong, Matthew K, Sugo, Tsukasa, Ruda, Vera M, Qin, June, Klebanov, Boris, Ciufolini, Marco, Akinc, Akin, Tam, Ying K, Hope, Michael J, Cullis, Pieter R
Publicado 2011

Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin

por Bolsoni, Juliana, Liu, Danny, Mohabatpour, Fatemeh, Ebner, Ronja, Sadhnani, Gaurav, Tafech, Belal, Leung, Jerry, Shanta, Selina, An, Kevin, Morin, Tessa, Chen, Yihang, Arguello, Alfonso, Choate, Keith, Jan, Eric, Ross, Colin J.D., Brambilla, Davide, Witzigmann, Dominik, Kulkarni, Jayesh, Cullis, Pieter R., Hedtrich, Sarah
Publicado 2023

Ca(V)3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons

por Cain, Stuart M., Tyson, John R., Choi, Hyun‐Beom, Ko, Rebecca, Lin, Paulo J. C., LeDue, Jeffrey M., Powell, Kim L., Bernier, Louis‐Philippe, Rungta, Ravi L., Yang, Yi, Cullis, Pieter R., O'Brien, Terence J., MacVicar, Brian A., Snutch, Terrance P.
Publicado 2018