Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

por Cunningham, Colm, Hennessy, Edel
Publicado 2015

Limiting antipsychotic drugs in dementia

por Macfarlane, Stephen, Cunningham, Colm
Publicado 2021

Non-Steroidal Anti-Inflammatory Drugs and Cognitive Function: Are Prostaglandins at the Heart of Cognitive Impairment in Dementia and Delirium ?

por Cunningham, Colm, Skelly, Donal Thomas
Publicado 2011

Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

por Murray, Carol L, Skelly, Donal T, Cunningham, Colm
Publicado 2011

When responsive and reactive meet organic? Treatment implications of language use in the era of #BanBPSD

por Macfarlane, Stephen, Atee, Mustafa, Morris, Thomas, Cunningham, Colm
Publicado 2021

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

por Skelly, Donal T., Hennessy, Edel, Dansereau, Marc-Andre, Cunningham, Colm
Publicado 2013

Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI(−/−) Mice

por Murray, Carol L., Obiang, Pauline, Bannerman, David, Cunningham, Colm
Publicado 2013

Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice

por Skelly, Donal T., Hennessy, Edel, Dansereau, Marc-Andre, Cunningham, Colm
Publicado 2013

Differential response of hippocampal and prefrontal oscillations to systemic LPS application

por Mamad, Omar, Islam, Md Nurul, Cunningham, Colm, Tsanov, Marian
Publicado 2018

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

por Field, Robert, Campion, Suzanne, Warren, Colleen, Murray, Carol, Cunningham, Colm
Publicado 2010

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease

por Hilton, Kathryn J., Cunningham, Colm, Reynolds, Richard A., Perry, V. Hugh
Publicado 2013

At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei

por Reis, Renata, Hennessy, Edel, Murray, Caoimhe, Griffin, Éadaoin W., Cunningham, Colm
Publicado 2015

Commentary on Pain Behaviors in Dementia: Letter to the Editor with Reference to the Article by Morrison et al. (2020)

por Atee, Mustafa, Morris, Thomas, Macfarlane, Stephen, Hughes, Jeffery D., Cunningham, Colm
Publicado 2021

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrP(Sc), even upon LPS stimulation

por Hughes, Martina M, Field, Robert H, Perry, V Hugh, Murray, Carol L, Cunningham, Colm
Publicado 2010

Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration

por Hennessy, Edel, Gormley, Shane, Lopez-Rodriguez, Ana Belen, Murray, Caoimhe, Murray, Carol, Cunningham, Colm
Publicado 2017

Evaluating the Clinical Impact of National Dementia Behaviour Support Programs on Neuropsychiatric Outcomes in Australia

por Macfarlane, Stephen, Atee, Mustafa, Morris, Thomas, Whiting, Daniel, Healy, Madeleine, Alford, Marie, Cunningham, Colm
Publicado 2021

Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation

por Cunningham, Orla, Campion, Suzanne, Perry, V Hugh, Murray, Carol, Sidenius, Nicolai, Docagne, Fabian, Cunningham, Colm
Publicado 2009

A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy

por Torvell, Megan, Hampton, David W., Connick, Peter, MacLullich, Alasdair M.J., Cunningham, Colm, Chandran, Siddharthan
Publicado 2019

Hippocampal Lesions can Enhance Discrimination Learning Despite Normal Sensitivity to Interference From Incidental Information

por Sanderson, David J, Rawlins, J Nicholas P, Deacon, Robert M J, Cunningham, Colm, Barkus, Chris, Bannerman, David M
Publicado 2012

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

por Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Publicado 2015