Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging

por D’Urso, Alessandro, Purrello, Roberto, Cunsolo, Alessandra, Milardi, Danilo, Fattorusso, Caterina, Persico, Marco, Gaczynska, Maria, Osmulski, Pawel A., Santoro, Anna Maria
Publicado 2023

Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study

por Santoro, Anna Maria, Monaco, Irene, Attanasio, Francesco, Lanza, Valeria, Pappalardo, Giuseppe, Tomasello, Marianna Flora, Cunsolo, Alessandra, Rizzarelli, Enrico, De Luigi, Ada, Salmona, Mario, Milardi, Danilo
Publicado 2016

Electrostatic Map Of Proteasome α-Rings Encodes The Design of Allosteric Porphyrin-Based Inhibitors Able To Affect 20S Conformation By Cooperative Binding

por Dato, Antonio Di, Cunsolo, Alessandra, Persico, Marco, Santoro, Anna Maria, D’Urso, Alessandro, Milardi, Danilo, Purrello, Roberto, Stefanelli, Manuela, Paolesse, Roberto, Tundo, Grazia R., Sbardella, Diego, Fattorusso, Caterina, Coletta, Massimo
Publicado 2017

Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution

por Persico, Marco, Santoro, Anna Maria, D’Urso, Alessandro, Milardi, Danilo, Purrello, Roberto, Cunsolo, Alessandra, Gobbo, Marina, Fattorusso, Roberto, Diana, Donatella, Stefanelli, Manuela, Tundo, Grazia R., Sbardella, Diego, Coletta, Massimo, Fattorusso, Caterina
Publicado 2022

Cationic porphyrins are tunable gatekeepers of the 20S proteasome

por Santoro, Anna M., Cunsolo, Alessandra, D'Urso, Alessandro, Sbardella, Diego, Tundo, Grazia R., Ciaccio, Chiara, Coletta, Massimiliano, Diana, Donatella, Fattorusso, Roberto, Persico, Marco, Di Dato, Antonio, Fattorusso, Caterina, Milardi, Danilo, Purrello, Roberto
Publicado 2016

Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States

por Santoro, Anna Maria, D’Urso, Alessandro, Cunsolo, Alessandra, Milardi, Danilo, Purrello, Roberto, Sbardella, Diego, Tundo, Grazia R., Diana, Donatella, Fattorusso, Roberto, Dato, Antonio Di, Paladino, Antonella, Persico, Marco, Coletta, Massimo, Fattorusso, Caterina
Publicado 2020