Targeting Ovarian Cancer with IL-2 Cytokine/Antibody Complexes: A Summary and Recent Advances

por Deng, Yilun, Reyes, Ryan M, Zhang, Chenghao, Conejo-Garcia, José, Curiel, Tyler J.
Publicado 2021

Parasite Mitogen-Activated Protein Kinases as Drug Discovery Targets to Treat Human Protozoan Pathogens

por Brumlik, Michael J., Pandeswara, Srilakshmi, Ludwig, Sara M., Murthy, Kruthi, Curiel, Tyler J.
Publicado 2011

Graft-versus-Host Disease Is Enhanced by Selective CD73 Blockade in Mice

por Wang, Long, Fan, Jie, Chen, Siqi, Zhang, Yi, Curiel, Tyler J., Zhang, Bin
Publicado 2013

421 Specific cephalosporin antibiotics deplete tumor PD-L1 to inhibit DNA damage sensing and sensitize to Chk1 inhibitors in vivo

por Murray, Clare, Kornepati, Anand, Padron, Alvaro, Deng, Yilun, Garcia, Myrna, Bai, Haiyan, Curiel, Tyler
Publicado 2022

4579 Distinct clinical and immunological responses to αPD-1, kαPD-L1 and αPD-L2 immunotherapy in B16 melanoma in aged versus young hosts includes T-cell stem cell effects and PD-L2...

por Garcia, Myrna G, Padron, Alvaro, Deng, Yilun, Gupta, Harshita, Kancharla, Aravind, Reyes, Ryan, Curiel, Tyler
Publicado 2020

Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

por Patel, Sukeshi, Hurez, Vincent, Nawrocki, Steffan T., Goros, Martin, Michalek, Joel, Sarantopoulos, John, Curiel, Tyler, Mahalingam, Devalingam
Publicado 2016

Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation

por Wu, Bogang, Chiang, Huai-Chin, Sun, Xiujie, Yuan, Bin, Mitra, Payal, Hu, Yanfen, Curiel, Tyler J, Li, Rong
Publicado 2020

Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) T(reg) cells are a source of tumour-associated T(reg) cells

por Downs-Canner, Stephanie, Berkey, Sara, Delgoffe, Greg M., Edwards, Robert P., Curiel, Tyler, Odunsi, Kunle, Bartlett, David L., Obermajer, Nataša
Publicado 2017

CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation

por Reyes, Ryan M, Zhang, Chenghao, Deng, Yilun, Ji, Niannian, Mukherjee, Neelam, Padron, Alvaro S, Clark, Curtis A, Svatek, Robert S, Curiel, Tyler J
Publicado 2021

PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner

por Wu, Bogang, Sun, Xiujie, Yuan, Bin, Ge, Fei, Gupta, Harshita B., Chiang, Huai-Chin, Li, Jingwei, Hu, Yanfen, Curiel, Tyler J., Li, Rong
Publicado 2020

Estrogen receptor beta signaling in CD8(+) T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

por Yuan, Bin, Clark, Curtis A, Wu, Bogang, Yang, Jing, Drerup, Justin M, Li, Tianbao, Jin, Victor X, Hu, Yanfen, Curiel, Tyler J, Li, Rong
Publicado 2021

Immune checkpoint expression and relationships to anti-PD-L1 immune checkpoint blockade cancer immunotherapy efficacy in aged versus young mice

por Garcia, Myrna G., Deng, Yilun, Murray, Clare, Reyes, Ryan M, Padron, Alvaro, Bai, Haiyan, Kancharla, Aravind, Gupta, Harshita, Shen-Orr, Shai, Curiel, Tyler J.
Publicado 2022

Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer

por Gupta, Harshita B, Clark, Curtis A, Yuan, Bin, Sareddy, Gangadhara, Pandeswara, Srilakshmi, Padron, Alvaro S, Hurez, Vincent, Conejo-Garcia, José, Vadlamudi, Ratna, Li, Rong, Curiel, Tyler J
Publicado 2016

Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

por Murray, Clare, Galvan, Eva, Ontiveros, Carlos, Deng, Yilun, Bai, Haiyan, Padron, Alvaro Souto, Hinchee-Rodriguez, Kathryn, Garcia, Myrna G., Kornepati, Anand, Conejo-Garcia, Jose, Curiel, Tyler J.
Publicado 2022

Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer

por Liu, Jinyou, Viswanadhapalli, Suryavathi, Garcia, Lauren, Zhou, Mei, Nair, Binoj C., Kost, Edward, Tekmal, Rajeshwar Rao, Li, Rong, Rao, Manjeet K., Curiel, Tyler, Vadlamudi, Ratna K., Sareddy, Gangadhara R.
Publicado 2017

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

por Kryczek, Ilona, Zou, Linhua, Rodriguez, Paulo, Zhu, Gefeng, Wei, Shuang, Mottram, Peter, Brumlik, Michael, Cheng, Pui, Curiel, Tyler, Myers, Leann, Lackner, Andrew, Alvarez, Xavier, Ochoa, Augusto, Chen, Lieping, Zou, Weiping
Publicado 2006

Intratumoral CD56(bright) natural killer cells are associated with improved survival in bladder cancer

por Mukherjee, Neelam, Ji, Niannian, Hurez, Vincent, Curiel, Tyler J., Montgomery, Maureen O., Braun, Andrew J., Nicolas, Marlo, Aguilera, Marcela, Kaushik, Dharam, Liu, Qianqian, Ruan, Jianhua, Kendrick, Kerri A., Svatek, Robert S.
Publicado 2018

Rapamycin enhances BCG-specific γδ T cells during intravesical BCG therapy for non-muscle invasive bladder cancer: a randomized, double-blind study

por Ji, Niannian, Mukherjee, Neelam, Reyes, Ryan M, Gelfond, Jonathan, Javors, Martin, Meeks, Joshua J., McConkey, David J, Shu, Zhen-Ju, Ramamurthy, Chethan, Dennett, Ryan, Curiel, Tyler J, Svatek, Robert S
Publicado 2021

p53 and rapamycin are additive

por Christy, Barbara, Demaria, Marco, Campisi, Judith, Huang, Jing, Jones, Diane, Dodds, Sherry G., Williams, Charnae, Hubbard, Gene, Livi, Carolina B., Gao, Xiaoli, Weintraub, Susan, Curiel, Tyler, Sharp, Z. Dave, Hasty, Paul
Publicado 2015

Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer

por Wu, Bogang, Sun, Xiujie, Gupta, Harshita B., Yuan, Bin, Li, Jingwei, Ge, Fei, Chiang, Huai-Chin, Zhang, Xiaowen, Zhang, Chi, Zhang, Deyi, Yang, Jing, Hu, Yanfen, Curiel, Tyler J., Li, Rong
Publicado 2018