Advances in nanomedicine drug delivery applications for HIV therapy

por Curley, Paul, Liptrott, Neill J, Owen, Andrew
Publicado 2017

Measuring the operational impact of digitized hospital records: a mixed methods study

por Scott, Philip J., Curley, Paul J., Williams, Paul B., Linehan, Ian P., Shaha, Steven H.
Publicado 2016

Towards a rational design of solid drug nanoparticles with optimised pharmacological properties

por Siccardi, Marco, Martin, Phillip, Smith, Darren, Curley, Paul, McDonald, Tom, Giardiello, Marco, Liptrott, Neill, Rannard, Steve, Owen, Andrew
Publicado 2016

Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies

por Hobson, James J., Al-khouja, Amer, Curley, Paul, Meyers, David, Flexner, Charles, Siccardi, Marco, Owen, Andrew, Meyers, Caren Freel, Rannard, Steve P.
Publicado 2019

Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations

por Hobson, James J., Curley, Paul, Savage, Alison C., Al-khouja, Amer, Siccardi, Marco, Flexner, Charles, Meyers, Caren Freel, Owen, Andrew, Rannard, Steve P.
Publicado 2019

Development of a highly sensitive bioanalytical assay for the quantification of favipiravir.

por Curley, Paul, Neary, Megan, Arshad, Usman, Tatham, Lee, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P, Owen, Andrew
Publicado 2021

Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.

por Neary, Megan, Arshad, Usman, Tatham, Lee, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P, Biagini, Giancarlo A, Curley, Paul, Owen, Andrew
Publicado 2021

Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters

por Gallardo-Toledo, Eduardo, Neary, Megan, Sharp, Joanne, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Curley, Paul, Arshad, Usman, Pertinez, Henry, Rajoli, Rajith K. R., Valentijn, Anthony, Cox, Helen, Tatham, Lee, Kipar, Anja, Stewart, James P., Owen, Andrew
Publicado 2023

Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an ex...

por Tatham, Lee, Kipar, Anja, Sharp, Joanne, Kijak, Edyta, Herriott, Joanne, Neary, Megan, Box, Helen, Toledo, Eduardo Gallardo, Valentijn, Anthony, Cox, Helen, Pertinez, Henry, Curley, Paul, Arshad, Usman, Rajoli, Rajith KR, Rannard, Steve, Stewart, James, Owen, Andrew
Publicado 2023

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations

por Curley, Paul, Hobson, James J., Liptrott, Neill J., Makarov, Edward, Al-khouja, Amer, Tatham, Lee, David, Christopher A. W., Box, Helen, Neary, Megan, Sharp, Joanne, Pertinez, Henry, Meyers, David, Flexner, Charles, Freel Meyers, Caren L., Poluektova, Larisa, Rannard, Steve, Owen, Andrew
Publicado 2023

Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays

por Box, Helen, Pennington, Shaun H, Kijak, Edyta, Tatham, Lee, Caygill, Claire H, Lopeman, Rose C, Jeffreys, Laura N, Herriott, Joanne, Sharp, Joanne, Neary, Megan, Valentijn, Anthony, Pertinez, Henry, Curley, Paul, Arshad, Usman, Rajoli, Rajith KR, Rannard, Steve, Stewart, James P., Biagini, Giancarlo A, Owen, Andrew
Publicado 2022

Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters

por Neary, Megan, Sharp, Joanne, Gallardo-Toledo, Eduardo, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Cox, Helen, Tatham, Lee, Box, Helen, Curley, Paul, Arshad, Usman, Rajoli, Rajith K. R., Pertinez, Henry, Valentijn, Anthony, Dhaliwal, Kevin, Mc Caughan, Frank, Hobson, James, Rannard, Steve, Kipar, Anja, Stewart, James P., Owen, Andrew
Publicado 2023

Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics

por Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith K. R., Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steve P., O’Neill, Paul M., Aljayyoussi, Ghaith, Pennington, Shaun H., Ward, Stephen A., Hill, Andrew, Back, David J., Khoo, Saye H., Bray, Patrick G., Biagini, Giancarlo A., Owen, Andrew
Publicado 2020

Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis

por Rajoli, Rajith K. R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun H., Hill, Andrew, Boffito, Marta, Ward, Steve A., Khoo, Saye H., Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo A., Owen, Andrew
Publicado 2020

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

por Brevini, Teresa, Maes, Mailis, Webb, Gwilym J., John, Binu V., Fuchs, Claudia D., Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L., Scott, William E., Pereyra-Gerber, Pehuén, Gelson, William T. H., Brown, Stephanie, Dillon, Scott, Muraro, Daniele, Sharp, Jo, Neary, Megan, Box, Helen, Tatham, Lee, Stewart, James, Curley, Paul, Pertinez, Henry, Forrest, Sally, Mlcochova, Petra, Varankar, Sagar S., Darvish-Damavandi, Mahnaz, Mulcahy, Victoria L., Kuc, Rhoda E., Williams, Thomas L., Heslop, James A., Rossetti, Davide, Tysoe, Olivia C., Galanakis, Vasileios, Vila-Gonzalez, Marta, Crozier, Thomas W. M., Bargehr, Johannes, Sinha, Sanjay, Upponi, Sara S., Fear, Corrina, Swift, Lisa, Saeb-Parsy, Kourosh, Davies, Susan E., Wester, Axel, Hagström, Hannes, Melum, Espen, Clements, Darran, Humphreys, Peter, Herriott, Jo, Kijak, Edyta, Cox, Helen, Bramwell, Chloe, Valentijn, Anthony, Illingworth, Christopher J. R., Dahman, Bassam, Bastaich, Dustin R., Ferreira, Raphaella D., Marjot, Thomas, Barnes, Eleanor, Moon, Andrew M., Barritt, Alfred S., Gupta, Ravindra K., Baker, Stephen, Davenport, Anthony P., Corbett, Gareth, Gorgoulis, Vassilis G., Buczacki, Simon J. A., Lee, Joo-Hyeon, Matheson, Nicholas J., Trauner, Michael, Fisher, Andrew J., Gibbs, Paul, Butler, Andrew J., Watson, Christopher J. E., Mells, George F., Dougan, Gordon, Owen, Andrew, Lohse, Ansgar W., Vallier, Ludovic, Sampaziotis, Fotios
Publicado 2022