Snapshots of the influenza virus transcription-replication machine in action and implications for anti-viral drug discovery

por Cusack, Stephen
Publicado 2020

Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2

por Schulze, Wiebke Manuela, Cusack, Stephen
Publicado 2017

Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription

por Reguera, Juan, Weber, Friedemann, Cusack, Stephen
Publicado 2010

An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase

por Reich, Stefan, Guilligay, Delphine, Cusack, Stephen
Publicado 2017

Structural snapshots of actively transcribing influenza polymerase

por Kouba, Tomas, Drncova, Petra, Cusack, Stephen
Publicado 2019

Chilaiditi’s Syndrome

por McNamara, Rosa F., Cusack, Stephen, Hallihan, Patrick
Publicado 2009

Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter

por Gerlach, Piotr, Malet, Hélène, Cusack, Stephen, Reguera, Juan
Publicado 2015

Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells

por Avilov, Sergiy, Magnus, Julie, Cusack, Stephen, Naffakh, Nadia
Publicado 2016

The mechanism of genome replication and transcription in bunyaviruses

por Malet, Hélène, Williams, Harry M., Cusack, Stephen, Rosenthal, Maria
Publicado 2023

Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5

por Louber, Jade, Brunel, Joanna, Uchikawa, Emiko, Cusack, Stephen, Gerlier, Denis
Publicado 2015

Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation

por Pellegrini, Erika, Signor, Luca, Singh, Saurabh, Boeri Erba, Elisabetta, Cusack, Stephen
Publicado 2017

Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting

por Schulze, Wiebke Manuela, Stein, Frank, Rettel, Mandy, Nanao, Max, Cusack, Stephen
Publicado 2018

Author Correction: Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting

por Schulze, Wiebke Manuela, Stein, Frank, Rettel, Mandy, Nanao, Max, Cusack, Stephen
Publicado 2018

Characterization of PA-N terminal domain of Influenza A polymerase reveals sequence specific RNA cleavage

por Datta, Kausiki, Wolkerstorfer, Andrea, Szolar, Oliver H. J., Cusack, Stephen, Klumpp, Klaus
Publicado 2013

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

por Uchikawa, Emiko, Lethier, Mathilde, Malet, Hélène, Brunel, Joanna, Gerlier, Denis, Cusack, Stephen
Publicado 2016

Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2

por Clerici, Marcello, Deniaud, Aurélien, Boehm, Volker, Gehring, Niels H., Schaffitzel, Christiane, Cusack, Stephen
Publicado 2014

RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction

por Louber, Jade, Kowalinski, Eva, Bloyet, Louis-Marie, Brunel, Joanna, Cusack, Stephen, Gerlier, Denis
Publicado 2014

Crystal structure of a signal recognition particle Alu domain in the elongation arrest conformation

por Bousset, Luc, Mary, Camille, Brooks, Mark A., Scherrer, Anne, Strub, Katharina, Cusack, Stephen
Publicado 2014

Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetase

por Palencia, Andrés, Crépin, Thibaut, Vu, Michael T., Lincecum, Tommie L., Martinis, Susan A., Cusack, Stephen
Publicado 2012

Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases

por Reguera, Juan, Gerlach, Piotr, Rosenthal, Maria, Gaudon, Stephanie, Coscia, Francesca, Günther, Stephan, Cusack, Stephen
Publicado 2016