The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues

por Pisaneschi, Federica, Lin, Yu-Hsi, Leonard, Paul G., Satani, Nikunj, Yan, Victoria C., Hammoudi, Naima, Raghavan, Sudhir, Link, Todd M., K. Georgiou, Dimitra, Czako, Barbara, Muller, Florian L.
Publicado 2019

Screening of Hydrocarbon-Stapled Peptides for Inhibition of Calcium-Triggered Exocytosis

por Lai, Ying, Tuvim, Michael J., Leitz, Jeremy, Peters, John, Pfuetzner, Richard A., Esquivies, Luis, Zhou, Qiangjun, Czako, Barbara, Cross, Jason B., Jones, Philip, Dickey, Burton F., Brunger, Axel T.
Publicado 2022

SF2312 is a natural phosphonate inhibitor of Enolase

por Leonard, Paul G., Satani, Nikunj, Maxwell, David, Lin, Yu-Hsi, Hammoudi, Naima, Peng, Zhenghong, Pisaneschi, Federica, Link, Todd M., Lee, Gilbert R., Sun, Duoli, Prasad, Basvoju A. Bhanu, Di Francesco, Maria Emilia, Czako, Barbara, Asara, John M., Wang, Y. Alan, Bornmann, William, DePinho, Ronald A., Muller, Florian L.
Publicado 2016

Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers

por Yan, Victoria C., Pham, Cong-Dat, Ballato, Elliot S., Yang, Kristine L., Arthur, Kenisha, Khadka, Sunada, Barekatain, Yasaman, Shrestha, Prakriti, Tran, Theresa, Poral, Anton H., Washington, Mykia, Raghavan, Sudhir, Czako, Barbara, Pisaneschi, Federica, Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Millward, Steven W., Muller, Florian L.
Publicado 2022

An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers

por Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Yan, Victoria C., Barekatain, Yasaman, Khadka, Sunada, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Pham, Cong-Dat, Arthur, Kenisha, Maxwell, David, Peng, Zhenghong, Leonard, Paul G., Czako, Barbara, Pisaneschi, Federica, Mandal, Pijus, Sun, Yuting, Zielinski, Rafal, Pando, Susana Castro, Wang, Xiaobo, Tran, Theresa, Xu, Quanyu, Wu, Qi, Jiang, Yongying, Kang, Zhijun, Asara, John M., Priebe, Waldemar, Bornmann, William, Marszalek, Joseph R., DePinho, Ronald A., Muller, Florian L.
Publicado 2020