Kinetic Landscape of a Peptide Bond-Forming Prolyl Oligopeptidase

por Czekster, Clarissa M., Naismith, James H.
Publicado 2017

Protein Mass-Modulated Effects in the Catalytic Mechanism of Dihydrofolate Reductase: Beyond Promoting Vibrations

por Wang, Zhen, Singh, Priyanka, Czekster, Clarissa M., Kohen, Amnon, Schramm, Vern L.
Publicado 2014

Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates

por Czekster, Clarissa M., Ludewig, Hannes, McMahon, Stephen A., Naismith, James H.
Publicado 2017

The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling

por Athukoralage, Januka S, Graham, Shirley, Rouillon, Christophe, Grüschow, Sabine, Czekster, Clarissa M, White, Malcolm F
Publicado 2020

Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

por Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Publicado 2021

Correction: Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

por Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Publicado 2021

Allosteric Activation Shifts the Rate-Limiting Step in a Short-Form ATP Phosphoribosyltransferase

por Fisher, Gemma, Thomson, Catherine M., Stroek, Rozanne, Czekster, Clarissa M., Hirschi, Jennifer S., da Silva, Rafael G.
Publicado 2018

Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates

por Ludewig, Hannes, Czekster, Clarissa M., Oueis, Emilia, Munday, Elizabeth S., Arshad, Mohammed, Synowsky, Silvia A., Bent, Andrew F., Naismith, James H.
Publicado 2018

Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase

por Fisher, Gemma, Pečaver, Ennio, Read, Benjamin J., Leese, Susannah K., Laing, Erin, Dickson, Alison L., Czekster, Clarissa M., da Silva, Rafael G.
Publicado 2023

The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent

por Bré, Jennifer, Dickson, Alison L., Read, Oliver J., Zhang, Ying, McKissock, Fiona G., Mullen, Peter, Tang, Peijun, Zickuhr, Greice M., Czekster, Clarissa M., Harrison, David J.
Publicado 2023

Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m(1)A22-tRNA methyltransferase TrmK

por Sweeney, Pamela, Galliford, Ashleigh, Kumar, Abhishek, Raju, Dinesh, Krishna, Naveen B., Sutherland, Emmajay, Leo, Caitlin J., Fisher, Gemma, Lalitha, Roopa, Muthuraj, Likith, Sigamani, Gladstone, Oehler, Verena, Synowsky, Silvia, Shirran, Sally L., Gloster, Tracey M., Czekster, Clarissa M., Kumar, Pravin, da Silva, Rafael G.
Publicado 2022