Critical importance of RAB proteins for synaptic function

por Mignogna, Maria Lidia, D'Adamo, Patrizia
Publicado 2017

Forebrain Deletion of αGDI in Adult Mice Worsens the Pre-Synaptic Deficit at Cortico-Lateral Amygdala Synaptic Connections

por Bianchi, Veronica, Gambino, Frédéric, Muzio, Luca, Toniolo, Daniela, Humeau, Yann, D'Adamo, Patrizia
Publicado 2012

Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury

por Cusimano, Melania, Brambilla, Elena, Capotondo, Alessia, De Feo, Donatella, Tomasso, Antonio, Comi, Giancarlo, D’Adamo, Patrizia, Muzio, Luca, Martino, Gianvito
Publicado 2018

Altered fronto-striatal functions in the Gdi1-null mouse model of X-linked Intellectual Disability

por Morè, Lorenzo, Künnecke, Basil, Yekhlef, Latefa, Bruns, Andreas, Marte, Antonella, Fedele, Ernesto, Bianchi, Veronica, Taverna, Stefano, Gatti, Silvia, D'Adamo, Patrizia
Publicado 2017

Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia

por Zanardi, Alan, Conti, Antonio, Cremonesi, Marco, D'Adamo, Patrizia, Gilberti, Enrica, Apostoli, Pietro, Cannistraci, Carlo Vittorio, Piperno, Alberto, David, Samuel, Alessio, Massimo
Publicado 2017

A CTNNA3 compound heterozygous deletion implicates a role for αT-catenin in susceptibility to autism spectrum disorder

por Bacchelli, Elena, Ceroni, Fabiola, Pinto, Dalila, Lomartire, Silvia, Giannandrea, Maila, D'Adamo, Patrizia, Bonora, Elena, Parchi, Piero, Tancredi, Raffaella, Battaglia, Agatino, Maestrini, Elena
Publicado 2014

A nonsense mutation in myelin protein zero causes congenital hypomyelination neuropathy through altered P0 membrane targeting and gain of abnormal function

por Fratta, Pietro, Ornaghi, Francesca, Dati, Gabriele, Zambroni, Desirée, Saveri, Paola, Belin, Sophie, D’Adamo, Patrizia, Shy, Michael, Quattrini, Angelo, Laura Feltri, M, Wrabetz, Lawrence
Publicado 2019

Clinical characterization of a novel RAB39B nonstop mutation in a family with ASD and severe ID causing RAB39B downregulation and study of a Rab39b knock down mouse model

por Mignogna, Maria Lidia, Ficarella, Romina, Gelmini, Susanna, Marzulli, Lucia, Ponzi, Emanuela, Gabellone, Alessandra, Peschechera, Antonia, Alessio, Massino, Margari, Lucia, Gentile, Mattia, D’Adamo, Patrizia
Publicado 2021

RAB39B-mediated trafficking of the GluA2-AMPAR subunit controls dendritic spine maturation and intellectual disability-related behaviour

por Mignogna, Maria Lidia, Musardo, Stefano, Ranieri, Giulia, Gelmini, Susanna, Espinosa, Pedro, Marra, Paolo, Belloli, Sara, Murtaj, Valentina, Moresco, Rosa Maria, Bellone, Camilla, D’Adamo, Patrizia
Publicado 2021

Niacin‐mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination

por Bolino, Alessandra, Piguet, Françoise, Alberizzi, Valeria, Pellegatta, Marta, Rivellini, Cristina, Guerrero‐Valero, Marta, Noseda, Roberta, Brombin, Chiara, Nonis, Alessandro, D'Adamo, Patrizia, Taveggia, Carla, Previtali, Stefano Carlo
Publicado 2016

Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2(−/y) Mice

por Murru, Luca, Vezzoli, Elena, Longatti, Anna, Ponzoni, Luisa, Falqui, Andrea, Folci, Alessandra, Moretto, Edoardo, Bianchi, Veronica, Braida, Daniela, Sala, Mariaelvina, D'Adamo, Patrizia, Bassani, Silvia, Francolini, Maura, Passafaro, Maria
Publicado 2017

Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome

por Valassina, Nicholas, Brusco, Simone, Salamone, Alessia, Serra, Linda, Luoni, Mirko, Giannelli, Serena, Bido, Simone, Massimino, Luca, Ungaro, Federica, Mazzara, Pietro Giuseppe, D’Adamo, Patrizia, Lignani, Gabriele, Broccoli, Vania, Colasante, Gaia
Publicado 2022

The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition

por Mignogna, Maria Lidia, Giannandrea, Maila, Gurgone, Antonia, Fanelli, Francesca, Raimondi, Francesco, Mapelli, Lisa, Bassani, Silvia, Fang, Huaqiang, Van Anken, Eelco, Alessio, Massimo, Passafaro, Maria, Gatti, Silvia, Esteban, José A., Huganir, Richard, D’Adamo, Patrizia
Publicado 2015

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks

por Pennucci, Roberta, Talpo, Francesca, Astro, Veronica, Montinaro, Valentina, Morè, Lorenzo, Cursi, Marco, Castoldi, Valerio, Chiaretti, Sara, Bianchi, Veronica, Marenna, Silvia, Cambiaghi, Marco, Tonoli, Diletta, Leocani, Letizia, Biella, Gerardo, D'Adamo, Patrizia, de Curtis, Ivan
Publicado 2016

Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits

por Zamboni, Valentina, Armentano, Maria, Sarò, Gabriella, Ciraolo, Elisa, Ghigo, Alessandra, Germena, Giulia, Umbach, Alessandro, Valnegri, Pamela, Passafaro, Maria, Carabelli, Valentina, Gavello, Daniela, Bianchi, Veronica, D’Adamo, Patrizia, de Curtis, Ivan, El-Assawi, Nadia, Mauro, Alessandro, Priano, Lorenzo, Ferri, Nicola, Hirsch, Emilio, Merlo, Giorgio R.
Publicado 2016

Neural precursor cells tune striatal connectivity through the release of IGFBPL1

por Butti, Erica, Cattaneo, Stefano, Bacigaluppi, Marco, Cambiaghi, Marco, Scotti, Giulia Maria, Brambilla, Elena, Ruffini, Francesca, Sferruzza, Giacomo, Ripamonti, Maddalena, Simeoni, Fabio, Cacciaguerra, Laura, Zanghì, Aurora, Quattrini, Angelo, Fesce, Riccardo, Panina-Bordignon, Paola, Giannese, Francesca, Cittaro, Davide, Kuhlmann, Tanja, D’Adamo, Patrizia, Rocca, Maria Assunta, Taverna, Stefano, Martino, Gianvito
Publicado 2022

Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion

por Fumagalli, Valeria, Ravà, Micol, Marotta, Davide, Di Lucia, Pietro, Laura, Chiara, Sala, Eleonora, Grillo, Marta, Bono, Elisa, Giustini, Leonardo, Perucchini, Chiara, Mainetti, Marta, Sessa, Alessandro, Garcia-Manteiga, José M., Donnici, Lorena, Manganaro, Lara, Delbue, Serena, Broccoli, Vania, De Francesco, Raffaele, D’Adamo, Patrizia, Kuka, Mirela, Guidotti, Luca G., Iannacone, Matteo
Publicado 2021

Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse

por D'Adamo, Patrizia, Horvat, Anemari, Gurgone, Antonia, Mignogna, Maria Lidia, Bianchi, Veronica, Masetti, Michela, Ripamonti, Maddalena, Taverna, Stefano, Velebit, Jelena, Malnar, Maja, Muhič, Marko, Fink, Katja, Bachi, Angela, Restuccia, Umberto, Belloli, Sara, Moresco, Rosa Maria, Mercalli, Alessia, Piemonti, Lorenzo, Potokar, Maja, Bobnar, Saša Trkov, Kreft, Marko, Chowdhury, Helena H., Stenovec, Matjaž, Vardjan, Nina, Zorec, Robert
Publicado 2021

Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients

por Sauer, Aisha V., Hernandez, Raisa Jofra, Fumagalli, Francesca, Bianchi, Veronica, Poliani, Pietro L., Dallatomasina, Chiara, Riboni, Elisa, Politi, Letterio S., Tabucchi, Antonella, Carlucci, Filippo, Casiraghi, Miriam, Carriglio, Nicola, Cominelli, Manuela, Forcellini, Carlo Alberto, Barzaghi, Federica, Ferrua, Francesca, Minicucci, Fabio, Medaglini, Stefania, Leocani, Letizia, la Marca, Giancarlo, Notarangelo, Lucia D., Azzari, Chiara, Comi, Giancarlo, Baldoli, Cristina, Canale, Sabrina, Sessa, Maria, D’Adamo, Patrizia, Aiuti, Alessandro
Publicado 2017