Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody

por Hinke, Simon A., Cieniewicz, Anne M., Kirchner, Thomas, D'Aquino, Katharine, Nanjunda, Rupesh, Aligo, Jason, Perkinson, Robert, Cooper, Philip, Boayke, Ken, Chiu, Mark L., Jarantow, Steve, Lacy, Eilyn R., Liang, Yin, Johnson, Dana L., Whaley, Jean M., Lingham, Russell B., Kihm, Anthony J.
Publicado 2018

The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression

por Benegiamo, Giorgia, von Alvensleben, Giacomo V.G., Rodríguez-López, Sandra, Goeminne, Ludger J.E., Bachmann, Alexis M., Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A., Azhar, Nabil, Reilly, Dermot F., D’Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan
Publicado 2023

Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity

por Camacho, Raul C., You, Seohee, D’Aquino, Katharine E., Li, Wenyu, Wang, Yuanping, Gunnet, Joseph, Littrell, James, Qi, Jian Shen, Kang, Lijuan, Jian, Wenying, MacDonald, Mary, Tat, Timothy, Steiner, Derek, Zhang, Yue-Mei, Lanter, James, Patch, Raymond, Zhang, Rui, Li, Jiali, Edavettal, Suzanne, Edwards, Wilson, Dinh, Thai, Wang, Li Ying, Connor, Judy, Hunter, Michael, Chi, Ellen, Swanson, Ronald V., Leonard, James N., Case, Martin A.
Publicado 2020