EU-Wide Access to High-quality, Affordable Precision Diagnostics: An EHA Position Paper

por Macintyre, Elizabeth, Gribben, John, Döhner, Konstanze
Publicado 2020

The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

por Gentle, Ian Edward, Moelter, Isabel, Badr, Mohamed Tarek, Döhner, Konstanze, Lübbert, Michael, Häcker, Georg
Publicado 2021

The Renovated Face of EHA Classical Master Class: A Survey-based Evaluation on Behalf of the EHA Campus Working Group

por Gurnari, Carmelo, Bouaziz, Malik, Marinova, Joana, van Havre, Nathalie, Döhner, Konstanze, Ar, Muhlis Cem
Publicado 2022

SEURAT: Visual analytics for the integrated analysis of microarray data

por Gribov, Alexander, Sill, Martin, Lück, Sonja, Rücker, Frank, Döhner, Konstanze, Bullinger, Lars, Benner, Axel, Unwin, Antony
Publicado 2010

Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms

por Kampa-Schittenhelm, Kerstin Maria, Heinrich, Michael Charles, Akmut, Figen, Döhner, Hartmut, Döhner, Konstanze, Schittenhelm, Marcus Matthias
Publicado 2013

P416: DNA METHYLATION-BASED CHARACTERIZATION OF ACUTE MYELOID LEUKEMIA POINTS TOWARDS KDM3B AS A 5Q HAPLOINSUFFICIENCY CANDIDATE

por Kelly, Katherine, Sollier, Etienne, Riedel, Anna, Welte, Linda, Jahn, Ekaterina, Döhner, Hartmut, Döhner, Konstanze, Lutsik, Pavlo, Plass, Christoph
Publicado 2023

TP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse model

por Pabst, Gabriel, Lind, Karin, Graf, Ricarda, Zebisch, Armin, Stölzel, Friedrich, Döhner, Konstanze, Heitzer, Ellen, Reinisch, Andreas, Sill, Heinz
Publicado 2020

Genetic alterations in Thai adult patients with acute myeloid leukemia and myelodysplastic syndrome—excess blasts detected by next-generation sequencing technique

por Owattanapanich, Weerapat, Herzig, Julia, Jahn, Nikolaus, Panina, Ekaterina, Ruchutrakool, Theera, Kungwankiattichai, Smith, Issaragrisil, Surapol, Döhner, Hartmut, Döhner, Konstanze
Publicado 2021

Functional Classification of TP53 Mutations in Acute Myeloid Leukemia

por Dutta, Sayantanee, Pregartner, Gudrun, Rücker, Frank G., Heitzer, Ellen, Zebisch, Armin, Bullinger, Lars, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz
Publicado 2020

P440: ENHANCER HIJACKING IN COMPLEX-KARYOTYPE AML

por Sollier, Etienne, Riedel, Anna, Kelly, Katherine, Weichenhan, Dieter, Jahn, Ekaterina, Döhner, Konstanze, Döhner, Hartmut, Ernst, Aurélie, Lutsik, Pavlo, Plass, Christoph
Publicado 2023

DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (V...

por Grishina, Olga, Schmoor, Claudia, Döhner, Konstanze, Hackanson, Björn, Lubrich, Beate, May, Annette M., Cieslik, Caroline, Müller, Michael J., Lübbert, Michael
Publicado 2015

getITD for FLT3-ITD-based MRD monitoring in AML

por Blätte, Tamara J., Schmalbrock, Laura K., Skambraks, Sabrina, Lux, Susanne, Cocciardi, Sibylle, Dolnik, Anna, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars
Publicado 2019

P453: NOVEL INSIGHTS INTO MINIMAL RESIDUAL DISEASE OF ACUTE MYELOID LEUKEMIA USING PRIMARY SAMPLES AND A CLINICALLY RELEVANT PDX MODEL.

por Aroua, Nesrine, Karpova, Darja, Leppä, Aino-Maija, Donato, Elisa, Przybylla, Adriana, Sohn, Markus, Zeisberger, Petra, Klein, Corinna, Döhner, Konstanze, Trumpp, Andreas
Publicado 2023

Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia

por Kampa-Schittenhelm, Kerstin Maria, Heinrich, Michael Charles, Akmut, Figen, Rasp, Katharina Henriette, Illing, Barbara, Döhner, Hartmut, Döhner, Konstanze, Schittenhelm, Marcus Matthias
Publicado 2013

Attenuated Expression of Apoptosis Stimulating Protein of p53-2 (ASPP2) in Human Acute Leukemia Is Associated with Therapy Failure

por Schittenhelm, Marcus M., Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D., Kampa-Schittenhelm, Kerstin M.
Publicado 2013

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia

por Prochazka, Katharina T., Pregartner, Gudrun, Rücker, Frank G., Heitzer, Ellen, Pabst, Gabriel, Wölfler, Albert, Zebisch, Armin, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz
Publicado 2019

Validation of myeloproliferative neoplasms associated risk factor RDW as predictor of thromboembolic complications in healthy individuals: analysis on 6849 participants of the SHIP...

por Manz, Kirsi, Bahr, Jeanette, Ittermann, Till, Döhner, Konstanze, Koschmieder, Steffen, Brümmendorf, Tim H., Griesshammer, Martin, Nauck, Matthias, Völzke, Henry, Heidel, Florian H.
Publicado 2023

Defining disease modification in myelofibrosis in the era of targeted therapy

por Pemmaraju, Naveen, Verstovsek, Srdan, Mesa, Ruben, Gupta, Vikas, Garcia, Jacqueline S., Scandura, Joseph M., Oh, Stephen T., Passamonti, Francesco, Döhner, Konstanze, Mead, Adam J.
Publicado 2022

Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen

por Schmutz, Maximilian, Zucknick, Manuela, Schlenk, Richard F., Mertens, Daniel, Benner, Axel, Weichenhan, Dieter, Mücke, Oliver, Döhner, Konstanze, Plass, Christoph, Bullinger, Lars, Claus, Rainer
Publicado 2023

Significant association of cutaneous adverse events with hydroxyurea: results from a prospective non-interventional study in BCR-ABL1-negative myeloproliferative neoplasms (MPN) -...

por Stegelmann, Frank, Wille, Kai, Busen, Hannah, Fuchs, Christiane, Schauer, Stefanie, Sadjadian, Parvis, Becker, Tatjana, Kolatzki, Vera, Döhner, Hartmut, Stadler, Rudolf, Döhner, Konstanze, Griesshammer, Martin
Publicado 2020