Immune checkpoint blockade can synergize with radiation therapy, even in tumors resistant to checkpoint monotherapy

por Dörrie, Jan
Publicado 2016

CSPG4 as Target for CAR-T-Cell Therapy of Various Tumor Entities–Merits and Challenges

por Harrer, Dennis C., Dörrie, Jan, Schaft, Niels
Publicado 2019

CARs: Beyond T Cells and T Cell-Derived Signaling Domains

por Sievers, Nico M., Dörrie, Jan, Schaft, Niels
Publicado 2020

CARs and Drugs: Pharmacological Ways of Boosting CAR-T-Cell Therapy

por Harrer, Dennis Christoph, Dörrie, Jan, Schaft, Niels
Publicado 2023

T-Cell Responses in Merkel Cell Carcinoma: Implications for Improved Immune Checkpoint Blockade and Other Therapeutic Options

por Gehrcken, Laura, Sauerer, Tatjana, Schaft, Niels, Dörrie, Jan
Publicado 2021

CSPG4-Specific CAR T Cells for High-Risk Childhood B Cell Precursor Leukemia

por Harrer, Dennis C., Schuler, Gerold, Dörrie, Jan, Schaft, Niels
Publicado 2019

Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update

por Dörrie, Jan, Schaft, Niels, Schuler, Gerold, Schuler-Thurner, Beatrice
Publicado 2020

Beyond Cancer: Regulation and Function of PD-L1 in Health and Immune-Related Diseases

por Beenen, Amke C., Sauerer, Tatjana, Schaft, Niels, Dörrie, Jan
Publicado 2022

Single-Molecule RNA Sequencing Reveals IFNγ-Induced Differential Expression of Immune Escape Genes in Merkel Cell Polyomavirus–Positive MCC Cell Lines

por Sauerer, Tatjana, Lischer, Christopher, Weich, Adrian, Berking, Carola, Vera, Julio, Dörrie, Jan
Publicado 2021

Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization

por Lai, Xin, Keller, Christine, Santos, Guido, Schaft, Niels, Dörrie, Jan, Vera, Julio
Publicado 2022

Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

por Knippertz, Ilka, Deinzer, Andrea, Dörrie, Jan, Schaft, Niels, Nettelbeck, Dirk M., Steinkasserer, Alexander
Publicado 2016

Just One Position-Independent Lysine Residue Can Direct MelanA into Proteasomal Degradation following N-Terminal Fusion of Ubiquitin

por Setz, Christian, Friedrich, Melanie, Hahn, Sabine, Dörrie, Jan, Schaft, Niels, Schuler, Gerold, Schubert, Ulrich
Publicado 2013

BRAF and MEK Inhibitors Affect Dendritic-Cell Maturation and T-Cell Stimulation

por Hoyer, Stefanie, Eberlein, Valentina, Schuler, Gerold, Berking, Carola, Heinzerling, Lucie, Schaft, Niels, Dörrie, Jan
Publicado 2021

BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy

por Dörrie, Jan, Babalija, Lek, Hoyer, Stefanie, Gerer, Kerstin F., Schuler, Gerold, Heinzerling, Lucie, Schaft, Niels
Publicado 2018

Clinical-Scale Production of CAR-T Cells for the Treatment of Melanoma Patients by mRNA Transfection of a CSPG4-Specific CAR under Full GMP Compliance

por Wiesinger, Manuel, März, Johannes, Kummer, Mirko, Schuler, Gerold, Dörrie, Jan, Schuler-Thurner, Beatrice, Schaft, Niels
Publicado 2019

Decitabine-Mediated Upregulation of CSPG4 in Ovarian Carcinoma Cells Enables Targeting by CSPG4-Specific CAR-T Cells

por Harrer, Dennis Christoph, Schenkel, Charlotte, Berking, Carola, Herr, Wolfgang, Abken, Hinrich, Dörrie, Jan, Schaft, Niels
Publicado 2022

Breaking Entry-and Species Barriers: LentiBOOST(®) Plus Polybrene Enhances Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5

por Strack, Astrid, Deinzer, Andrea, Thirion, Christian, Schrödel, Silke, Dörrie, Jan, Sauerer, Tatjana, Steinkasserer, Alexander, Knippertz, Ilka
Publicado 2022

A One-Armed Phase I Dose Escalation Trial Design: Personalized Vaccination with IKKβ-Matured, RNA-Loaded Dendritic Cells for Metastatic Uveal Melanoma

por Koch, Elias A. T., Schaft, Niels, Kummer, Mirko, Berking, Carola, Schuler, Gerold, Hasumi, Kenichiro, Dörrie, Jan, Schuler-Thurner, Beatrice
Publicado 2022

Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells

por Shimizu, Kanako, Shinga, Jun, Yamasaki, Satoru, Kawamura, Masami, Dörrie, Jan, Schaft, Niels, Sato, Yusuke, Iyoda, Tomonori, Fujii, Shin-ichiro
Publicado 2015

NF-κB activation triggers NK-cell stimulation by monocyte-derived dendritic cells

por Bosch, Naomi C., Voll, Reinhard E., Voskens, Caroline J., Gross, Stefanie, Seliger, Barbara, Schuler, Gerold, Schaft, Niels, Dörrie, Jan
Publicado 2019