Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

por Sarhan, Dhifaf, D’Arcy, Padraig, Lundqvist, Andreas
Publicado 2014

Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19

por Clemente, Valentino, D’Arcy, Padraig, Bazzaro, Martina
Publicado 2020

Proteasome-associated deubiquitinases and cancer

por Mofers, Arjan, Pellegrini, Paola, Linder, Stig, D’Arcy, Pádraig
Publicado 2017

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics

por Girgis, Adel S., D'Arcy, Padraig, Aboshouk, Dalia R., Bekheit, Mohamed S.
Publicado 2022

Oncogenic Functions of the Cancer-Testis Antigen SSX on the Proliferation, Survival, and Signaling Pathways of Cancer Cells

por D’Arcy, Padraig, Maruwge, Wessen, Wolahan, Barry, Ma, Limin, Brodin, Bertha
Publicado 2014

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors

por Zhang, Xiaonan, de Milito, Angelo, Olofsson, Maria Hägg, Gullbo, Joachim, D’Arcy, Padraig, Linder, Stig
Publicado 2015

Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment

por Zhang, Xiaonan, Espinosa, Belén, Saei, Amir Ata, D'Arcy, Padraig, Zubarev, Roman A., Linder, Stig
Publicado 2019

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

por Mofers, Arjan, Perego, Paola, Selvaraju, Karthik, Gatti, Laura, Gullbo, Joachim, Linder, Stig, D'Arcy, Padraig
Publicado 2019

MYC is downregulated by a mitochondrial checkpoint mechanism

por Zhang, Xiaonan, Mofers, Arjan, Hydbring, Per, Olofsson, Maria Hägg, Guo, Jing, Linder, Stig, D'Arcy, Padraig
Publicado 2017

Sorafenib inhibits tumor growth and vascularization of rhabdomyosarcoma cells by blocking IGF-1R-mediated signaling

por Maruwge, Wessen, D’Arcy, Pádraig, Folin, Annika, Brnjic, Slavica, Wejde, Johan, Davis, Anthony, Erlandsson, Fredrik, Bergh, Jonas, Brodin, Bertha
Publicado 2008

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

por Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Wang, Xin, Pellegrini, Paola, Olofsson, Maria Hägg, Selvaraju, Karthik, D’Arcy, Padraig, Linder, Stig
Publicado 2017

Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570

por Pellegrini, Paola, Selvaraju, Karthik, Faustini, Elena, Mofers, Arjan, Zhang, Xiaonan, Ternerot, Jens, Schubert, Alice, Linder, Stig, D′Arcy, Pádraig
Publicado 2020

Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System

por Selvaraju, Karthik, Lotfi, Kourosh, Gubat, Johannes, Miquel, Maria, Nilsson, Amanda, Hill, Julia, Jensen, Lasse D., Linder, Stig, D’Arcy, Pádraig
Publicado 2021

Elevation of Proteasomal Substrate Levels Sensitizes Cells to Apoptosis Induced by Inhibition of Proteasomal Deubiquitinases

por Sun, Chao, Roboti, Peristera, Puumalainen, Marjo-Riitta, Fryknäs, Mårten, Wang, Xin, D'Arcy, Padraig, Hult, Malin, High, Stephen, Linder, Stig, Swanton, Eileithyia
Publicado 2014

A drug screening assay on cancer cells chronically adapted to acidosis

por Pellegrini, Paola, Serviss, Jason T., Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D’Arcy, Padraig, Linder, Stig, De Milito, Angelo
Publicado 2018

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mecha...

por Gubat, Johannes, Selvaraju, Karthik, Sjöstrand, Linda, Kumar Singh, Dhananjay, Turkina, Maria V., Schmierer, Bernhard, Sabatier, Pierre, Zubarev, Roman A., Linder, Stig, D’Arcy, Pádraig
Publicado 2022

The deubiquitinase USP8 regulates ovarian cancer cell response to cisplatin by suppressing apoptosis

por Corno, Cristina, D’Arcy, Padraig, Bagnoli, Marina, Paolini, Biagio, Costantino, Matteo, Carenini, Nives, Corna, Elisabetta, Alberti, Paola, Mezzanzanica, Delia, Colombo, Diego, Linder, Stig, Arrighetti, Noemi, Perego, Paola
Publicado 2022

Iron chelators target both proliferating and quiescent cancer cells

por Fryknäs, Mårten, Zhang, Xiaonan, Bremberg, Ulf, Senkowski, Wojciech, Olofsson, Maria Hägg, Brandt, Peter, Persson, Ingmar, D’Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Schughart, Leoni Kunz, Linder, Stig, Larsson, Rolf
Publicado 2016

The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

por Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Publicado 2016

Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

por Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Publicado 2016