A novel, non-neuronal acetylcholinesterase of schistosome parasites is essential for definitive host infection

por Skelly, Patrick J., Da’dara, Akram A.
Publicado 2023

The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin

por Wang, Qiang, Da’dara, Akram A., Skelly, Patrick J.
Publicado 2017

The blood fluke Schistosoma mansoni cleaves the coagulation protein high molecular weight kininogen (HK) but does not generate the vasodilator bradykinin

por Wang, Qiang, Da’dara, Akram A., Skelly, Patrick J.
Publicado 2018

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis

por Nation, Catherine S., Da’Dara, Akram A., Skelly, Patrick J.
Publicado 2020

Schistosome immunomodulators

por Acharya, Sreemoyee, Da’dara, Akram A., Skelly, Patrick J.
Publicado 2021

Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase enhances formation of the blood-clot lysis protein plasmin

por Pirovich, David B., Da'dara, Akram A., Skelly, Patrick J.
Publicado 2020

Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target

por Pirovich, David B., Da’dara, Akram A., Skelly, Patrick J.
Publicado 2021

Schistosoma mansoni phosphoglycerate mutase: a glycolytic ectoenzyme with thrombolytic potential

por Pirovich, David B., Da’dara, Akram A., Skelly, Patrick J.
Publicado 2022

Schistosomes Impede ATP-Induced T Cell Apoptosis In Vitro: The Role of Ectoenzyme SmNPP5

por Nation, Catherine S., Da’dara, Akram A., Elzoheiry, Manal, Skelly, Patrick J.
Publicado 2022

Schistosome migration in the definitive host

por Nation, Catherine S., Da’dara, Akram A., Marchant, Jeffrey K., Skelly, Patrick J.
Publicado 2020

Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides

por Da’dara, Akram A., Bhardwaj, Rita, Ali, Yasser B.M., Skelly, Patrick J.
Publicado 2014

Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase

por Figueiredo, Barbara C., Da'dara, Akram A., Oliveira, Sergio C., Skelly, Patrick J.
Publicado 2015

Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA

por Da’dara, Akram A., Angeli, Andrea, Ferraroni, Marta, Supuran, Claudiu T., Skelly, Patrick J.
Publicado 2019

Vitamin B6 Acquisition and Metabolism in Schistosoma mansoni

por Da’dara, Akram A., Elzoheiry, Manal, El-Beshbishi, Samar N., Skelly, Patrick J.
Publicado 2021

Schistosome Feeding and Regurgitation

por Skelly, Patrick J., Da'dara, Akram A., Li, Xiao-Hong, Castro-Borges, William, Wilson, R. Alan
Publicado 2014

Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from Schistosoma mansoni, a Platyhelminth Parasite Responsible for Schistosomiasis

por Angeli, Andrea, Pinteala, Mariana, Maier, Stelian S., Simionescu, Bogdan C., Da’dara, Akram A., Skelly, Patrick J., Supuran, Claudiu T.
Publicado 2020

Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Prot...

por Krautz-Peterson, Greice, Debatis, Michelle, Tremblay, Jacqueline M., Oliveira, Sergio C., Da’dara, Akram A., Skelly, Patrick J., Shoemaker, Charles B.
Publicado 2017

Prime-Boost Vaccine Regimen for SjTPI and SjC23 Schistosome Vaccines, Increases Efficacy in Water Buffalo in a Field Trial in China

por Da'Dara, Akram A., Li, Changlin, Yu, Xinling, Zheng, Mao, Zhou, Jie, Shollenberger, Lisa M., Li, Yue-sheng, Harn, Donald A.
Publicado 2019

Intravascular Schistosoma mansoni Cleave the Host Immune and Hemostatic Signaling Molecule Sphingosine-1-Phosphate via Tegumental Alkaline Phosphatase

por Elzoheiry, Manal, Da’dara, Akram A., Bhardwaj, Rita, Wang, Qiang, Azab, Manar S., El-Kholy, El-Saeed I., El-Beshbishi, Samar N., Skelly, Patrick J.
Publicado 2018

Schistosome Syntenin Partially Protects Vaccinated Mice against Schistosoma mansoni Infection

por Figueiredo, Barbara C., Assis, Natan R. G., Morais, Suellen B., Ricci, Natasha D., Pinheiro, Carina S., Martins, Vicente P., Bicalho, Rodrigo M., Da'dara, Akram A., Skelly, Patrick J., Oliveira, Sergio C.
Publicado 2014