Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment

por Klatt, Denise, Ha, Teng-Cheong, Schinke, Maximilian, Selich, Anton, Lieske, Anna, Dahlke, Julia, Morgan, Michael, Maetzig, Tobias, Schambach, Axel
Publicado 2020

Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants

por Dahlke, Julia, Schott, Juliane W., Vollmer Barbosa, Philippe, Klatt, Denise, Selich, Anton, Lachmann, Nico, Morgan, Michael, Moritz, Thomas, Schambach, Axel
Publicado 2021

Real-Time Characterization of Clonal Fate Decisions in Complex Leukemia Samples by Fluorescent Genetic Barcoding

por Maetzig, Tobias, Lieske, Anna, Dörpmund, Nicole, Rothe, Michael, Kleppa, Marc-Jens, Dziadek, Violetta, Hassan, Jacob Jalil, Dahlke, Julia, Borchert, Dorit, Schambach, Axel
Publicado 2022

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages

por Lipus, Alexandra, Janosz, Ewa, Ackermann, Mania, Hetzel, Miriam, Dahlke, Julia, Buchegger, Theresa, Wunderlich, Stephanie, Martin, Ulrich, Cathomen, Toni, Schambach, Axel, Moritz, Thomas, Lachmann, Nico
Publicado 2020

Targeted Repair of p47-CGD in iPSCs by CRISPR/Cas9: Functional Correction without Cleavage in the Highly Homologous Pseudogenes

por Klatt, Denise, Cheng, Erica, Philipp, Friederike, Selich, Anton, Dahlke, Julia, Schmidt, Reinhold E., Schott, Juliane W., Büning, Hildegard, Hoffmann, Dirk, Thrasher, Adrian J., Schambach, Axel
Publicado 2019

Improved Activity against Acute Myeloid Leukemia with Chimeric Antigen Receptor (CAR)-NK-92 Cells Designed to Target CD123

por Morgan, Michael A., Kloos, Arnold, Lenz, Daniela, Kattre, Nadine, Nowak, Juliette, Bentele, Marco, Keisker, Maximilian, Dahlke, Julia, Zimmermann, Katharina, Sauer, Martin, Heuser, Michael, Schambach, Axel
Publicado 2021