Xrn1-resistant RNA structures are well-conserved within the genus flavivirus

por Dilweg, Ivar W., Bouabda, Assia, Dalebout, Tim, Gultyaev, Alexander P., Bredenbeek, Peter J., Olsthoorn, R. C. L.
Publicado 2020

A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses

por Oreshkova, Nadia, Myeni, Sebenzile K., Mishra, Niraj, Albulescu, Irina C., Dalebout, Tim J., Snijder, Eric J., Bredenbeek, Peter J., Dallmeier, Kai, Kikkert, Marjolein
Publicado 2021

Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activit...

por Bailey-Elkin, Ben A., Knaap, Robert C. M., Johnson, Garrett G., Dalebout, Tim J., Ninaber, Dennis K., van Kasteren, Puck B., Bredenbeek, Peter J., Snijder, Eric J., Kikkert, Marjolein, Mark, Brian L.
Publicado 2014

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

por Rabouw, Huib H., Langereis, Martijn A., Knaap, Robert C. M., Dalebout, Tim J., Canton, Javier, Sola, Isabel, Enjuanes, Luis, Bredenbeek, Peter J., Kikkert, Marjolein, de Groot, Raoul J., van Kuppeveld, Frank J. M.
Publicado 2016

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

por Ogando, Natacha S., Dalebout, Tim J., Zevenhoven-Dobbe, Jessika C., Limpens, Ronald W.A.L., van der Meer, Yvonne, Caly, Leon, Druce, Julian, de Vries, Jutte J. C., Kikkert, Marjolein, Bárcena, Montserrat, Sidorov, Igor, Snijder, Eric J.
Publicado 2020

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

por Zhang, Wei, Bailey-Elkin, Ben A., Knaap, Robert C. M., Khare, Baldeep, Dalebout, Tim J., Johnson, Garrett G., van Kasteren, Puck B., McLeish, Nigel J., Gu, Jun, He, Wenguang, Kikkert, Marjolein, Mark, Brian L., Sidhu, Sachdev S.
Publicado 2017

Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase

por Myeni, Sebenzile K., Bredenbeek, Peter J., Knaap, Robert C. M., Dalebout, Tim J., Morales, Shessy Torres, Sidorov, Igor A., Linger, Marissa E., Oreshkova, Nadia, van Zanen-Gerhardt, Sophie, Zander, Serge A. L., Enjuanes, Luis, Sola, Isabel, Snijder, Eric J., Kikkert, Marjolein
Publicado 2023

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

por Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Publicado 2020

Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

por van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Publicado 2021

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

por Fougeroux, Cyrielle, Goksøyr, Louise, Idorn, Manja, Soroka, Vladislav, Myeni, Sebenzile K., Dagil, Robert, Janitzek, Christoph M., Søgaard, Max, Aves, Kara-Lee, Horsted, Emma W., Erdoğan, Sayit Mahmut, Gustavsson, Tobias, Dorosz, Jerzy, Clemmensen, Stine, Fredsgaard, Laurits, Thrane, Susan, Vidal-Calvo, Elena E., Khalifé, Paul, Hulen, Thomas M., Choudhary, Swati, Theisen, Michael, Singh, Susheel K., Garcia-Senosiain, Asier, Van Oosten, Linda, Pijlman, Gorben, Hierzberger, Bettina, Domeyer, Tanja, Nalewajek, Blanka W., Strøbæk, Anette, Skrzypczak, Magdalena, Andersson, Laura F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, Tim J., Iversen, Kasper, Harritshøj, Lene H., Mordmüller, Benjamin, Ullum, Henrik, Reinert, Line S., de Jongh, Willem Adriaan, Kikkert, Marjolein, Paludan, Søren R., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Sander, Adam F.
Publicado 2021

Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

por Solforosi, Laura, Kuipers, Harmjan, Jongeneelen, Mandy, Rosendahl Huber, Sietske K., van der Lubbe, Joan E.M., Dekking, Liesbeth, Czapska-Casey, Dominika N., Izquierdo Gil, Ana, Baert, Miranda R.M., Drijver, Joke, Vaneman, Joost, van Huizen, Ella, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, de Wilde, Adriaan H., Kourkouta, Eleni, Custers, Jerome, van der Vlugt, Remko, Veldman, Daniel, Huizingh, Jeroen, Kaszas, Krisztian, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Barouch, Dan H., Böszörményi, Kinga P., Stammes, Marieke A., Kondova, Ivanela, Verschoor, Ernst J., Verstrepen, Babs E., Koopman, Gerrit, Mooij, Petra, Bogers, Willy M.J.M., van Heerden, Marjolein, Muchene, Leacky, Tolboom, Jeroen T.B.M., Roozendaal, Ramon, Brandenburg, Boerries, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C.
Publicado 2021