How Thymocyte Deletion in the Cortex May Curtail Antigen-Specific T-Regulatory Cell Development in the Medulla

por Wang, Chenglong, Daley, Stephen R.
Publicado 2022

Helios marks strongly autoreactive CD4(+) T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB

por Daley, Stephen R., Hu, Daniel Y., Goodnow, Christopher C.
Publicado 2013

DOCK8 deficiency diminishes thymic T‐regulatory cell development but not thymic deletion

por Randall, Katrina L, Law, Hsei Di, Ziolkowski, Andrew F, Wirasinha, Rushika C, Goodnow, Christopher C, Daley, Stephen R
Publicado 2021

Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus

por Szeto, Christopher, Zareie, Pirooz, Wirasinha, Rushika C., Zhang, Justin B., Nguyen, Andrea T., Riboldi-Tunnicliffe, Alan, La Gruta, Nicole L., Gras, Stephanie, Daley, Stephen R.
Publicado 2022

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells

por Silva, Diego G., Daley, Stephen R., Hogan, Jennifer, Lee, Sau K., Teh, Charis E., Hu, Daniel Y., Lam, Kong-Peng, Goodnow, Christopher C., Vinuesa, Carola G.
Publicado 2011

Ocular antigen does not cause disease unless presented in the context of inflammation

por Voigt, Valentina, Wikstrom, Matthew E., Kezic, Jelena M., Schuster, Iona S., Fleming, Peter, Makinen, Kimmo, Daley, Stephen R., Andoniou, Christopher E., Degli-Esposti, Mariapia A., Forrester, John V.
Publicado 2017

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2

por Barthlott, Thomas, Handel, Adam E., Teh, Hong Ying, Wirasinha, Rushika C., Hafen, Katrin, Žuklys, Saulius, Roch, Benoit, Orkin, Stuart H., de Villartay, Jean-Pierre, Daley, Stephen R., Holländer, Georg A.
Publicado 2021

SATB1 ensures appropriate transcriptional programs within naïve CD8(+) T cells

por Nüssing, Simone, Miosge, Lisa A, Lee, Kah, Olshansky, Moshe, Barugahare, Adele, Roots, Carla M, Sontani, Yovina, Day, E Bridie, Koutsakos, Marios, Kedzierska, Katherine, Goodnow, Christopher C, Russ, Brendan E, Daley, Stephen R, Turner, Stephen J
Publicado 2022

Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution

por Delmonte, Ottavia M., Castagnoli, Riccardo, Yu, Jason, Dvorak, Christopher C., Cowan, Morton J., Dávila Saldaña, Blachy J., De Ravin, Suk See, Mamcarz, Ewelina, Chang, Catherine K., Daley, Stephen R., Griffith, Linda M., Notarangelo, Luigi D., Puck, Jennifer M.
Publicado 2022

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios(+) T cells and autoantibodies

por Daley, Stephen R, Coakley, Kristen M, Hu, Daniel Y, Randall, Katrina L, Jenne, Craig N, Limnander, Andre, Myers, Darienne R, Polakos, Noelle K, Enders, Anselm, Roots, Carla, Balakishnan, Bhavani, Miosge, Lisa A, Sjollema, Geoff, Bertram, Edward M, Field, Matthew A, Shao, Yunli, Andrews, T Daniel, Whittle, Belinda, Barnes, S Whitney, Walker, John R, Cyster, Jason G, Goodnow, Christopher C, Roose, Jeroen P
Publicado 2013

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility

por Wirasinha, Rushika C., Davies, Ainsley R., Srivastava, Monika, Sheridan, Julie M., Sng, Xavier Y.X., Delmonte, Ottavia M., Dobbs, Kerry, Loh, Khai L., Miosge, Lisa A., Lee, Cindy Eunhee, Chand, Rochna, Chan, Anna, Yap, Jin Yan, Keller, Michael D., Chen, Karin, Rossjohn, Jamie, La Gruta, Nicole L., Vinuesa, Carola G., Reid, Hugh H., Lionakis, Michail S., Notarangelo, Luigi D., Gray, Daniel H.D., Goodnow, Christopher C., Cook, Matthew C., Daley, Stephen R.
Publicado 2020