Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity

por Freier, Regina, Dall, Elfriede, Brandstetter, Hans
Publicado 2015

Legumain Activity Is Controlled by Extended Active Site Residues and Substrate Conformation

por Elamin, Tasneem, Brandstetter, Hans, Dall, Elfriede
Publicado 2022

Structure and Mechanism of an Aspartimide-Dependent Peptide Ligase in Human Legumain**

por Dall, Elfriede, Fegg, Julia C, Briza, Peter, Brandstetter, Hans
Publicado 2015

Structural analyses of Arabidopsis thaliana legumain γ reveal differential recognition and processing of proteolysis and ligation substrates

por Zauner, Florian B., Elsässer, Brigitta, Dall, Elfriede, Cabrele, Chiara, Brandstetter, Hans
Publicado 2018

Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction

por Elamin, Tasneem, Santos, Naiá P., Briza, Peter, Brandstetter, Hans, Dall, Elfriede
Publicado 2022

Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations

por Elsässer, Brigitta, Zauner, Florian B., Messner, Johann, Soh, Wai Tuck, Dall, Elfriede, Brandstetter, Hans
Publicado 2017

Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states

por Dall, Elfriede, Hollerweger, Julia C., Dahms, Sven O., Cui, Haissi, Häussermann, Katharina, Brandstetter, Hans
Publicado 2018

Legumain Functions as a Transient TrkB Sheddase

por Holzner, Christoph, Böttinger, Katharina, Blöchl, Constantin, Huber, Christian G., Dahms, Sven O., Dall, Elfriede, Brandstetter, Hans
Publicado 2023

The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities

por Dall, Elfriede, Stanojlovic, Vesna, Demir, Fatih, Briza, Peter, Dahms, Sven O., Huesgen, Pitter F., Cabrele, Chiara, Brandstetter, Hans
Publicado 2021

ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease

por Soh, Wai Tuck, Demir, Fatih, Dall, Elfriede, Perrar, Andreas, Dahms, Sven O., Kuppusamy, Maithreyan, Brandstetter, Hans, Huesgen, Pitter F.
Publicado 2020

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition

por Dall, Elfriede, Zauner, Florian B., Soh, Wai Tuck, Demir, Fatih, Dahms, Sven O., Cabrele, Chiara, Huesgen, Pitter F., Brandstetter, Hans
Publicado 2020

Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S

por Soh, Wai Tuck, Briza, Peter, Dall, Elfriede, Asam, Claudia, Schubert, Mario, Huber, Sara, Aglas, Lorenz, Bohle, Barbara, Ferreira, Fatima, Brandstetter, Hans
Publicado 2017

Comparing Proteolytic Fingerprints of Antigen-Presenting Cells during Allergen Processing

por Hofer, Heidi, Weidinger, Tamara, Briza, Peter, Asam, Claudia, Wolf, Martin, Twaroch, Teresa E., Stolz, Frank, Neubauer, Angela, Dall, Elfriede, Hammerl, Peter, Jacquet, Alain, Wallner, Michael
Publicado 2017

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease

por Zhang, Zhentao, Obianyo, Obiamaka, Dall, Elfriede, Du, Yuhong, Fu, Haian, Liu, Xia, Kang, Seong Su, Song, Mingke, Yu, Shan-Ping, Cabrele, Chiara, Schubert, Mario, Li, Xiaoguang, Wang, Jian-Zhi, Brandstetter, Hans, Ye, Keqiang
Publicado 2017

Laser‐facilitated epicutaneous immunotherapy with hypoallergenic beta‐glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of aller...

por Korotchenko, Evgeniia, Schießl, Viktoria, Scheiblhofer, Sandra, Schubert, Mario, Dall, Elfriede, Joubert, Isabella A., Strandt, Helen, Neuper, Theresa, Sarajlic, Muamera, Bauer, Renate, Geppert, Mark, Joedicke, David, Wildner, Sabrina, Schaller, Susanne, Winkler, Stephan, Gadermaier, Gabriele, Horejs‐Hoeck, Jutta, Weiss, Richard
Publicado 2020