Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC

por Zoppoli, Gabriele, Douarre, Céline, Dalla Rosa, Ilaria, Liu, Hongfang, Reinhold, William, Pommier, Yves
Publicado 2011

Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria

por Zhang, Hongliang, Zhang, Yong-Wei, Yasukawa, Takehiro, Dalla Rosa, Ilaria, Khiati, Salim, Pommier, Yves
Publicado 2014

TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs

por Huang, Shar-yin N., Murai, Junko, Dalla Rosa, Ilaria, Dexheimer, Thomas S., Naumova, Alena, Gmeiner, William H., Pommier, Yves
Publicado 2013

Mitochondrial Topoisomerase I is Critical for Mitochondrial Integrity and Cellular Energy Metabolism

por Douarre, Céline, Sourbier, Carole, Dalla Rosa, Ilaria, Brata Das, Benu, Redon, Christophe E., Zhang, Hongliang, Neckers, Len, Pommier, Yves
Publicado 2012

Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I

por Sobek, Stefan, Dalla Rosa, Ilaria, Pommier, Yves, Bornholz, Beatrice, Kalfalah, Faiza, Zhang, Hongliang, Wiesner, Rudolf J., von Kleist-Retzow, Jürgen-Christoph, Hillebrand, Frank, Schaal, Heiner, Mielke, Christian, Christensen, Morten O., Boege, Fritz
Publicado 2013

LETM1 couples mitochondrial DNA metabolism and nutrient preference

por Durigon, Romina, Mitchell, Alice L, Jones, Aleck WE, Manole, Andreea, Mennuni, Mara, Hirst, Elizabeth MA, Houlden, Henry, Maragni, Giuseppe, Lattante, Serena, Doronzio, Paolo Niccolo’, Dalla Rosa, Ilaria, Zollino, Marcella, Holt, Ian J, Spinazzola, Antonella
Publicado 2018

MPV17L2 is required for ribosome assembly in mitochondria

por Dalla Rosa, Ilaria, Durigon, Romina, Pearce, Sarah F., Rorbach, Joanna, Hirst, Elizabeth M.A., Vidoni, Sara, Reyes, Aurelio, Brea-Calvo, Gloria, Minczuk, Michal, Woellhaf, Michael W., Herrmann, Johannes M., Huynen, Martijn A., Holt, Ian J., Spinazzola, Antonella
Publicado 2014

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

por Moss, Chloe F., Dalla Rosa, Ilaria, Hunt, Lilian E., Yasukawa, Takehiro, Young, Robert, Jones, Aleck W. E., Reddy, Kaalak, Desai, Radha, Virtue, Sam, Elgar, Greg, Voshol, Peter, Taylor, Martin S., Holt, Ian J., Reijns, Martin A. M., Spinazzola, Antonella
Publicado 2017

Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late‐onset disorder of mitochondrial DNA maintenance

por Sommerville, Ewen W., Dalla Rosa, Ilaria, Rosenberg, Masha M., Bruni, Francesco, Thompson, Kyle, Rocha, Mariana, Blakely, Emma L., He, Langping, Falkous, Gavin, Schaefer, Andrew M., Yu‐Wai‐Man, Patrick, Chinnery, Patrick F., Hedstrom, Lizbeth, Spinazzola, Antonella, Taylor, Robert W., Gorman, Gráinne S.
Publicado 2019

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

por Dalla Rosa, Ilaria, Cámara, Yolanda, Durigon, Romina, Moss, Chloe F., Vidoni, Sara, Akman, Gokhan, Hunt, Lilian, Johnson, Mark A., Grocott, Sarah, Wang, Liya, Thorburn, David R., Hirano, Michio, Poulton, Joanna, Taylor, Robert W., Elgar, Greg, Martí, Ramon, Voshol, Peter, Holt, Ian J., Spinazzola, Antonella
Publicado 2016

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism

por Desai, Radha, Frazier, Ann E., Durigon, Romina, Patel, Harshil, Jones, Aleck W., Dalla Rosa, Ilaria, Lake, Nicole J., Compton, Alison G., Mountford, Hayley S., Tucker, Elena J., Mitchell, Alice L. R., Jackson, Deborah, Sesay, Abdul, Di Re, Miriam, van den Heuvel, Lambert P., Burke, Derek, Francis, David, Lunke, Sebastian, McGillivray, George, Mandelstam, Simone, Mochel, Fanny, Keren, Boris, Jardel, Claude, Turner, Anne M., Ian Andrews, P., Smeitink, Jan, Spelbrink, Johannes N., Heales, Simon J., Kohda, Masakazu, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi, Lombès, Anne, Holt, Ian J., Thorburn, David R., Spinazzola, Antonella
Publicado 2017