Pathological alleles of MPV17 modeled in the yeast Saccharomyces cerevisiae orthologous gene SYM1 reveal their inability to take part in a high molecular weight complex

por Gilberti, Micol, Baruffini, Enrico, Donnini, Claudia, Dallabona, Cristina
Publicado 2018

Epigenetic Alterations in Prescription Opioid Misuse: New Strategies for Precision Pain Management

por Gerra, Maria Carla, Dallabona, Cristina, Arendt-Nielsen, Lars
Publicado 2021

Polymorphisms in DNA polymerase γ affect the mtDNA stability and the NRTI-induced mitochondrial toxicity in Saccharomyces cerevisiae

por Baruffini, Enrico, Ferrari, Jessica, Dallabona, Cristina, Donnini, Claudia, Lodi, Tiziana
Publicado 2015

Drug Drop Test: How to Quickly Identify Potential Therapeutic Compounds for Mitochondrial Diseases Using Yeast Saccharomyces cerevisiae

por Magistrati, Martina, Gilea, Alexandru Ionut, Gerra, Maria Carla, Baruffini, Enrico, Dallabona, Cristina
Publicado 2023

DNA polymerase γ and disease: what we have learned from yeast

por Lodi, Tiziana, Dallabona, Cristina, Nolli, Cecilia, Goffrini, Paola, Donnini, Claudia, Baruffini, Enrico
Publicado 2015

Modopathies Caused by Mutations in Genes Encoding for Mitochondrial RNA Modifying Enzymes: Molecular Mechanisms and Yeast Disease Models

por Magistrati, Martina, Gilea, Alexandru Ionut, Ceccatelli Berti, Camilla, Baruffini, Enrico, Dallabona, Cristina
Publicado 2023

Mitochondrial Aminoacyl-tRNA Synthetase and Disease: The Yeast Contribution for Functional Analysis of Novel Variants

por Figuccia, Sonia, Degiorgi, Andrea, Ceccatelli Berti, Camilla, Baruffini, Enrico, Dallabona, Cristina, Goffrini, Paola
Publicado 2021

A Yeast-Based Repurposing Approach for the Treatment of Mitochondrial DNA Depletion Syndromes Led to the Identification of Molecules Able to Modulate the dNTP Pool

por di Punzio, Giulia, Gilberti, Micol, Baruffini, Enrico, Lodi, Tiziana, Donnini, Claudia, Dallabona, Cristina
Publicado 2021

Elongator-dependent modification of cytoplasmic tRNA(Lys)(UUU) is required for mitochondrial function under stress conditions

por Tigano, Marco, Ruotolo, Roberta, Dallabona, Cristina, Fontanesi, Flavia, Barrientos, Antoni, Donnini, Claudia, Ottonello, Simone
Publicado 2015

Modeling human Coenzyme A synthase mutation in yeast reveals altered mitochondrial function, lipid content and iron metabolism

por Ceccatelli Berti, Camilla, Dallabona, Cristina, Lazzaretti, Mirca, Dusi, Sabrina, Tosi, Elena, Tiranti, Valeria, Goffrini, Paola
Publicado 2015

Yeast expression of mammalian Onzin and fungal FCR1 suggests ancestral functions of PLAC8 proteins in mitochondrial metabolism and DNA repair

por Daghino, Stefania, Di Vietro, Luigi, Petiti, Luca, Martino, Elena, Dallabona, Cristina, Lodi, Tiziana, Perotto, Silvia
Publicado 2019

The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases

por Ceccatelli Berti, Camilla, di Punzio, Giulia, Dallabona, Cristina, Baruffini, Enrico, Goffrini, Paola, Lodi, Tiziana, Donnini, Claudia
Publicado 2021

Saccharomyces cerevisiae as a Tool for Studying Mutations in Nuclear Genes Involved in Diseases Caused by Mitochondrial DNA Instability

por Gilea, Alexandru Ionut, Ceccatelli Berti, Camilla, Magistrati, Martina, di Punzio, Giulia, Goffrini, Paola, Baruffini, Enrico, Dallabona, Cristina
Publicado 2021

A Homozygous Mutation in LYRM7/MZM1L Associated with Early Onset Encephalopathy, Lactic Acidosis, and Severe Reduction of Mitochondrial Complex III Activity

por Invernizzi, Federica, Tigano, Marco, Dallabona, Cristina, Donnini, Claudia, Ferrero, Ileana, Cremonte, Maurizio, Ghezzi, Daniele, Lamperti, Costanza, Zeviani, Massimo
Publicado 2013

Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development i...

por Dallabona, Cristina, Pioli, Marianna, Spadola, Giorgio, Orsoni, Nicolò, Bisceglie, Franco, Lodi, Tiziana, Pelosi, Giorgio, Restivo, Francesco Maria, Degola, Francesca
Publicado 2019

A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

por di Punzio, Giulia, Di Noia, Maria Antonietta, Delahodde, Agnès, Sellem, Carole, Donnini, Claudia, Palmieri, Luigi, Lodi, Tiziana, Dallabona, Cristina
Publicado 2021

In Vivo Treatment with a Standardized Green Tea Extract Restores Cardiomyocyte Contractility in Diabetic Rats by Improving Mitochondrial Function through SIRT1 Activation

por Vilella, Rocchina, Izzo, Simona, Naponelli, Valeria, Savi, Monia, Bocchi, Leonardo, Dallabona, Cristina, Gerra, Maria Carla, Stilli, Donatella, Bettuzzi, Saverio
Publicado 2022

Decline of cardiomyocyte contractile performance and bioenergetic function in socially stressed male rats

por Barbetti, Margherita, Vilella, Rocchina, Dallabona, Cristina, Gerra, Maria Carla, Bocchi, Leonardo, Ielpo, Donald, Andolina, Diego, Sgoifo, Andrea, Savi, Monia, Carnevali, Luca
Publicado 2022

Mutations in the mitochondrial tryptophanyl‐tRNA synthetase cause growth retardation and progressive leukoencephalopathy

por Maffezzini, Camilla, Laine, Isabelle, Dallabona, Cristina, Clemente, Paula, Calvo‐Garrido, Javier, Wibom, Rolf, Naess, Karin, Barbaro, Michela, Falk, Anna, Donnini, Claudia, Freyer, Christoph, Wredenberg, Anna, Wedell, Anna
Publicado 2019

In-frame deletion in canine PITRM1 is associated with a severe early-onset epilepsy, mitochondrial dysfunction and neurodegeneration

por Hytönen, Marjo K., Sarviaho, Riika, Jackson, Christopher B., Syrjä, Pernilla, Jokinen, Tarja, Matiasek, Kaspar, Rosati, Marco, Dallabona, Cristina, Baruffini, Enrico, Quintero, Ileana, Arumilli, Meharji, Monteuuis, Geoffray, Donner, Jonas, Anttila, Marjukka, Suomalainen, Anu, Bindoff, Laurence A., Lohi, Hannes
Publicado 2021