Bi-Epitope SPR Surfaces: A Solution to Develop Robust Immunoassays

por Peng, Li, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F.
Publicado 2014

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

por Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall’Acqua, William F, Damschroder, Melissa M
Publicado 2015

Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-interferon antibody fragment and human interferon α-2A

por Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall’Acqua, William F.
Publicado 2008

Molecular basis for the antagonistic activity of an anti-CXCR4 antibody

por Peng, Li, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall'Acqua, William F.
Publicado 2015

Molecular basis for the mechanism of action of an anti-TACE antibody

por Peng, Li, Cook, Kimberly, Xu, Linda, Cheng, Li, Damschroder, Melissa, Gao, Changshou, Wu, Herren, Dall'Acqua, William F.
Publicado 2016

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action

por Geoghegan, James C., Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F., Wu, Herren, Dall'Acqua, William F., Damschroder, Melissa M.
Publicado 2016

Mechanisms of Neutralization of a Human Anti-α-toxin Antibody

por Oganesyan, Vaheh, Peng, Li, Damschroder, Melissa M., Cheng, Li, Sadowska, Agnieszka, Tkaczyk, Christine, Sellman, Bret R., Wu, Herren, Dall'Acqua, William F.
Publicado 2014

Generation and Characterization of an IgG4 Monomeric Fc Platform

por Shan, Lu, Colazet, Magali, Rosenthal, Kim L., Yu, Xiang-Qing, Bee, Jared S., Ferguson, Andrew, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Oganesyan, Vaheh
Publicado 2016

Long-acting antibody ligand mimetics for HER4-selective agonism

por Shan, Lu, Cook, Kimberly M., Haskins, Nantaporn, Omar, Bilal, Jiang, Yu, Garcia, Andrew, Koksal, Adem, Oganesyan, Vaheh, Rosenthal, Kim, Wu, Herren, Dall’Acqua, William F., Damschroder, Melissa M.
Publicado 2020

Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non–small-cell lung carcinoma and rodent tumor models

por Allen, Kevin L., Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall’Acqua, William F., Borrok, M. Jack, Damschroder, Melissa M., Tsui, Ping, Li, Qing
Publicado 2020

Correction: Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non–small-cell lung carcinoma and rodent tumor models

por Allen, Kevin L., Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall’Acqua, William F., Borrok, M. Jack, Damschroder, Melissa M., Tsui, Ping, Li, Qing
Publicado 2021

Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy

por Varkey, Reena, Du, Qun, Karnell, Jodi L., Xiao, Xiaodong, Casey, Kerry A., Woods, Rob, Rosenthal, Kim, Wilson, Susan, Dall’Acqua, William F., Wu, Herren, Herbst, Ronald, Ettinger, Rachel, Damschroder, Melissa
Publicado 2019

The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA

por Peng, Li, Oberst, Michael D., Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A., Wu, Herren, Yao, Yihong, Coats, Steven R., Dall’Acqua, William, Damschroder, Melissa, Hammond, Scott A.
Publicado 2012

Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody

por Oganesyan, Vaheh, Peng, Li, Bee, Jared S., Li, John, Perry, Samuel R., Comer, Frank, Xu, Linda, Cook, Kimberly, Senthil, Kannaki, Clarke, Lori, Rosenthal, Kim, Gao, Changshou, Damschroder, Melissa, Wu, Herren, Dall'Acqua, William
Publicado 2018

Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design

por Cannon, Daniel A., Shan, Lu, Du, Qun, Shirinian, Lena, Rickert, Keith W., Rosenthal, Kim L., Korade, Martin, van Vlerken-Ysla, Lilian E., Buchanan, Andrew, Vaughan, Tristan J., Damschroder, Melissa M., Popovic, Bojana
Publicado 2019

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

por Shan, Lu, Dyk, Nydia Van, Haskins, Nantaporn, Cook, Kimberly M., Rosenthal, Kim L., Mazor, Ronit, Dragulin-Otto, Sonia, Jiang, Yu, Wu, Herren, Dall’Acqua, William F., Borrok, Martin J., Damschroder, Melissa M., Oganesyan, Vaheh
Publicado 2021

Targeting CD73 in the tumor microenvironment with MEDI9447

por Hay, Carl M., Sult, Erin, Huang, Qihui, Mulgrew, Kathy, Fuhrmann, Stacy R., McGlinchey, Kelly A., Hammond, Scott A., Rothstein, Raymond, Rios-Doria, Jonathan, Poon, Edmund, Holoweckyj, Nick, Durham, Nicholas M., Leow, Ching Ching, Diedrich, Gundo, Damschroder, Melissa, Herbst, Ronald, Hollingsworth, Robert E., Sachsenmeier, Kris F.
Publicado 2016

Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies

por Dippel, Andrew, Gallegos, Austin, Aleti, Vineela, Barnes, Arnita, Chen, Xiaoru, Christian, Elizabeth, Delmar, Jared, Du, Qun, Esfandiary, Reza, Farmer, Erika, Garcia, Andrew, Li, Qing, Lin, Jia, Liu, Weiyi, Machiesky, LeeAnn, Mody, Neil, Parupudi, Arun, Prophet, Meagan, Rickert, Keith, Rosenthal, Kim, Ren, Song, Shandilya, Harini, Varkey, Reena, Wons, Kevin, Wu, Yuling, Loo, Yueh-Ming, Esser, Mark T., Kallewaard, Nicole L., Rajan, Sarav, Damschroder, Melissa, Xu, Weichen, Kaplan, Gilad
Publicado 2022

Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer

por Zanvit, Peter, van Dyk, Dewald, Fazenbaker, Christine, McGlinchey, Kelly, Luo, Weichuan, Pezold, Jessica M., Meekin, John, Chang, Chien-ying, Carrasco, Rosa A., Breen, Shannon, Cheung, Crystal Sao-Fong, Endlich-Frazier, Ariel, Clark, Benjamin, Chu, Nina J., Vantellini, Alessio, Martin, Philip L., Hoover, Clare E., Riley, Kenesha, Sweet, Steve M., Chain, David, Kim, Yeoun Jin, Tu, Eric, Harder, Nathalie, Phipps, Sandrina, Damschroder, Melissa, Gilbreth, Ryan N., Cobbold, Mark, Moody, Gordon, Bosco, Emily E.
Publicado 2023