A multi-encoder variational autoencoder controls multiple transformational features in single-cell image analysis

por Ternes, Luke, Dane, Mark, Gross, Sean, Labrie, Marilyne, Mills, Gordon, Gray, Joe, Heiser, Laura, Chang, Young Hwan
Publicado 2022

Analysis and modeling of cancer drug responses using cell cycle phase-specific rate effects

por Gross, Sean M., Mohammadi, Farnaz, Sanchez-Aguila, Crystal, Zhan, Paulina J., Liby, Tiera A., Dane, Mark A., Meyer, Aaron S., Heiser, Laura M.
Publicado 2023

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

por King, Carly J., Woodward, Josha, Schwartzman, Jacob, Coleman, Daniel J., Lisac, Robert, Wang, Nicholas J., Van Hook, Kathryn, Gao, Lina, Urrutia, Joshua, Dane, Mark A., Heiser, Laura M., Alumkal, Joshi J.
Publicado 2017

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

por Watson, Spencer S., Dane, Mark, Chin, Koei, Tatarova, Zuzana, Liu, Moqing, Liby, Tiera, Thompson, Wallace, Smith, Rebecca, Nederlof, Michel, Bucher, Elmar, Kilburn, David, Whitman, Matthew, Sudar, Damir, Mills, Gordon B., Heiser, Laura M., Jonas, Oliver, Gray, Joe W., Korkola, James E.
Publicado 2018

An altered extracellular matrix–integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells

por Hernandez, Sarah J, Lim, Ryan G, Onur, Tarik, Dane, Mark A, Smith, Rebecca, Wang, Keona, Jean, Grace En-Hway, Reyes-Ortiz, Andrea, Devlin, Kaylyn, Miramontes, Ricardo, Wu, Jie, Casale, Malcolm, Kilburn, David, Heiser, Laura M, Korkola, James E, Van Vactor, David, Botas, Juan, Thompson-Peer, Katherine L, Thompson, Leslie M
Publicado 2022

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

por Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., A. Dane, Mark, Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, W. Wood, Kenneth, Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Publicado 2016

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

por Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., Dane, Mark A., Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, Wood, Kenneth W., Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Publicado 2017

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

por Gross, Sean M., Dane, Mark A., Smith, Rebecca L., Devlin, Kaylyn L., McLean, Ian C., Derrick, Daniel S., Mills, Caitlin E., Subramanian, Kartik, London, Alexandra B., Torre, Denis, Evangelista, John Erol, Clarke, Daniel J. B., Xie, Zhuorui, Erdem, Cemal, Lyons, Nicholas, Natoli, Ted, Pessa, Sarah, Lu, Xiaodong, Mullahoo, James, Li, Jonathan, Adam, Miriam, Wassie, Brook, Liu, Moqing, Kilburn, David F., Liby, Tiera A., Bucher, Elmar, Sanchez-Aguila, Crystal, Daily, Kenneth, Omberg, Larsson, Wang, Yunguan, Jacobson, Connor, Yapp, Clarence, Chung, Mirra, Vidovic, Dusica, Lu, Yiling, Schurer, Stephan, Lee, Albert, Pillai, Ajay, Subramanian, Aravind, Papanastasiou, Malvina, Fraenkel, Ernest, Feiler, Heidi S., Mills, Gordon B., Jaffe, Jake D., Ma’ayan, Avi, Birtwistle, Marc R., Sorger, Peter K., Korkola, James E., Gray, Joe W., Heiser, Laura M.
Publicado 2022