Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants

por Nguyen, Trinh-Don, Dang, Thu-Thuy T.
Publicado 2021

Editorial: Exploring and Engineering Plant Specialized Metabolism: Latest Advances and New Horizons

por Franke, Jakob, Zhang, Yang, Dang, Thu-Thuy T.
Publicado 2021

Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina

por Dang, Thu‐Thuy T., Franke, Jakob, Tatsis, Evangelos, O'Connor, Sarah E.
Publicado 2017

Quantitation of Select Terpenes/Terpenoids and Nicotine Using Gas Chromatography–Mass Spectrometry with High-Temperature Headspace Sampling

por Nguyen, Trinh-Don, Riordan-Short, Seamus, Dang, Thu-Thuy T., O’Brien, Rob, Noestheden, Matthew
Publicado 2020

Discovery of a cytochrome P450 enzyme catalyzing the formation of spirooxindole alkaloid scaffold

por Nguyen, Tuan-Anh M., Grzech, Dagny, Chung, Khoa, Xia, Zhicheng, Nguyen, Trinh-Don, Dang, Thu-Thuy T.
Publicado 2023

Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes

por Dang, Thu-Thuy T, Franke, Jakob, Teto Carqueijeiro, Inês Soares, Langley, Chloe, Courdavault, Vincent, O’Connor, Sarah E.
Publicado 2018

Discovering and harnessing oxidative enzymes for chemoenzymatic synthesis and diversification of anticancer camptothecin analogues

por Nguyen, Tuan-Anh M., Nguyen, Trinh-Don, Leung, Yuen Yee, McConnachie, Matthew, Sannikov, Oleg, Xia, Zhicheng, Dang, Thu-Thuy T.
Publicado 2021

Discovery of a Short‐Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid

por Stavrinides, Anna K., Tatsis, Evangelos C., Dang, Thu‐Thuy, Caputi, Lorenzo, Stevenson, Clare E. M., Lawson, David M., Schneider, Bernd, O'Connor, Sarah E.
Publicado 2018

Directed Biosynthesis of Mitragynine Stereoisomers

por Schotte, Carsten, Jiang, Yindi, Grzech, Dagny, Dang, Thu-Thuy T., Laforest, Larissa C., León, Francisco, Mottinelli, Marco, Nadakuduti, Satya Swathi, McCurdy, Christopher R., O’Connor, Sarah E.
Publicado 2023

The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health

por Brose, Julia, Lau, Kin H, Dang, Thu Thuy Thi, Hamilton, John P, Martins, Lívia do Vale, Hamberger, Britta, Hamberger, Bjoern, Jiang, Jiming, O’Connor, Sarah E, Buell, C Robin
Publicado 2021

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

por Tatsis, Evangelos C., Carqueijeiro, Inês, Dugé de Bernonville, Thomas, Franke, Jakob, Dang, Thu-Thuy T., Oudin, Audrey, Lanoue, Arnaud, Lafontaine, Florent, Stavrinides, Anna K., Clastre, Marc, Courdavault, Vincent, O’Connor, Sarah E.
Publicado 2017

The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids

por Stander, Emily Amor, Lehka, Beata, Carqueijeiro, Inês, Cuello, Clément, Hansson, Frederik G., Jansen, Hans J., Dugé De Bernonville, Thomas, Birer Williams, Caroline, Vergès, Valentin, Lezin, Enzo, Lorensen, Marcus Daniel Brandbjerg Bohn, Dang, Thu-Thuy, Oudin, Audrey, Lanoue, Arnaud, Durand, Mickael, Giglioli-Guivarc’h, Nathalie, Janfelt, Christian, Papon, Nicolas, Dirks, Ron P., O’connor, Sarah Ellen, Jensen, Michael Krogh, Besseau, Sébastien, Courdavault, Vincent
Publicado 2023