Mechanisms of inhibition of viral RNA replication by nucleotide analogs

por Johnson, Kenneth A., Dangerfield, Tyler
Publicado 2021

Conformational dynamics during high-fidelity DNA replication and translocation defined using a DNA polymerase with a fluorescent artificial amino acid

por Dangerfield, Tyler L., Johnson, Kenneth A.
Publicado 2020

Substrate Specificity and Kinetics of RNA Hydrolysis by SARS-CoV-2 NSP10/14 Exonuclease

por Dangerfield, Tyler L., Johnson, Kenneth A.
Publicado 2022

Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication

por Dangerfield, Tyler L., Johnson, Kenneth A.
Publicado 2022

Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid

por Dangerfield, Tyler L., Kirmizialtin, Serdal, Johnson, Kenneth A.
Publicado 2021

Substrate specificity and proposed structure of the proofreading complex of T7 DNA polymerase

por Dangerfield, Tyler L., Kirmizialtin, Serdal, Johnson, Kenneth A.
Publicado 2022

Remdesivir Is Effective in Combating COVID-19 because It Is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase

por Dangerfield, Tyler L., Huang, Nathan Z., Johnson, Kenneth A.
Publicado 2020

Expression and purification of tag-free SARS-CoV-2 RNA-dependent RNA polymerase in Escherichia coli

por Dangerfield, Tyler L., Huang, Nathan Z., Johnson, Kenneth A.
Publicado 2021

Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication

por Bravo, Jack P.K., Dangerfield, Tyler L., Taylor, David W., Johnson, Kenneth A.
Publicado 2021

Kinetics of elementary steps in loop-mediated isothermal amplification (LAMP) show that strand invasion during initiation is rate-limiting

por Dangerfield, Tyler L, Paik, Inyup, Bhadra, Sanchita, Johnson, Kenneth A, Ellington, Andrew D
Publicado 2022

Structural basis for mismatch surveillance by CRISPR–Cas9

por Bravo, Jack P. K., Liu, Mu-Sen, Hibshman, Grace N., Dangerfield, Tyler L., Jung, Kyungseok, McCool, Ryan S., Johnson, Kenneth A., Taylor, David W.
Publicado 2022

Publisher Correction: Structural basis for mismatch surveillance by CRISPR–Cas9

por Bravo, Jack P. K., Liu, Mu-Sen, Hibshman, Grace N., Dangerfield, Tyler L., Jung, Kyungseok, McCool, Ryan S., Johnson, Kenneth A., Taylor, David W.
Publicado 2022

Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC

por Fagan, Sean P, Mukherjee, Purba, Jaremko, William J, Nelson-Rigg, Rachel, Wilson, Ryan C, Dangerfield, Tyler L, Johnson, Kenneth A, Lahiri, Indrajit, Pata, Janice D
Publicado 2021

Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage

por Schwartz, Evan A., Bravo, Jack P.K., Ahsan, Mohd, Macias, Luis A., McCafferty, Caitlyn L., Dangerfield, Tyler L., Walker, Jada N., Brodbelt, Jennifer S., Palermo, Giulia, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Publicado 2023