Challenges in translational drug research in neuropathic and inflammatory pain: the prerequisites for a new paradigm

por Taneja, A., Della Pasqua, O., Danhof, M.
Publicado 2017

Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development

por Visser, S A G, Manolis, E, Danhof, M, Kerbusch, T
Publicado 2013

Disease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women

por Berkhout, J, Stone, JA, Verhamme, KM, Danhof, M, Post, TM
Publicado 2016

Understanding the Behavior of Systems Pharmacology Models Using Mathematical Analysis of Differential Equations: Prolactin Modeling as a Case Study

por Bakshi, S, de Lange, EC, van der Graaf, PH, Danhof, M, Peletier, LA
Publicado 2016

Application of a Systems Pharmacology-Based Placebo Population Model to Analyze Long-Term Data of Postmenopausal Osteoporosis

por Berkhout, J, Stone, JA, Verhamme, KM, Stricker, BH, Sturkenboom, MC, Danhof, M, Post, TM
Publicado 2015

Prediction of Disease Progression, Treatment Response and Dropout in Chronic Obstructive Pulmonary Disease (COPD)

por Musuamba, F. T., Teutonico, D., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.
Publicado 2014

Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques

por Teutonico, D., Musuamba, F., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.
Publicado 2015

Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans

por Dubois, V. F. S., de Witte, W. E. A., Visser, S. A. G., Danhof, M., Della Pasqua, O.
Publicado 2015

Levofloxacin‐Induced QTc Prolongation Depends on the Time of Drug Administration

por Kervezee, L, Gotta, V, Stevens, J, Birkhoff, W, Kamerling, IMC, Danhof, M, Meijer, JH, Burggraaf, J
Publicado 2016

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1‐OH‐midazolam in morbidly obese and weight loss surgery patients

por Brill, MJE, Välitalo, PAJ, Darwich, AS, van Ramshorst, B, van Dongen, HPA, Rostami–Hodjegan, A, Danhof, M, Knibbe, CAJ
Publicado 2015

From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part I–Extrapolation of a Covariate Model From Morphine to Zidovudine

por Krekels, E H J, Neely, M, Panoilia, E, Tibboel, D, Capparelli, E, Danhof, M, Mirochnick, M, Knibbe, C A J
Publicado 2012

From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part II—Sensitivity to Physiological and Physicochemical Properties

por Krekels, E H J, Johnson, T N, den Hoedt, S M, Rostami-Hodjegan, A, Danhof, M, Tibboel, D, Knibbe, C A J
Publicado 2012