Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models

por Danhof, Meindert
Publicado 2015

CAR-T-Zell-Therapie beim multiplen Myelom

por Zhou, X., Einsele, H., Danhof, S.
Publicado 2021

Bispecific Antibodies: A New Era of Treatment for Multiple Myeloma

por Zhou, Xiang, Einsele, Hermann, Danhof, Sophia
Publicado 2020

The impact of composite AUC estimates on the prediction of systemic exposure in toxicology experiments

por Sahota, Tarjinder, Danhof, Meindert, Della Pasqua, Oscar
Publicado 2015

Challenges in translational drug research in neuropathic and inflammatory pain: the prerequisites for a new paradigm

por Taneja, A., Della Pasqua, O., Danhof, M.
Publicado 2017

Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development

por Visser, S A G, Manolis, E, Danhof, M, Kerbusch, T
Publicado 2013

Characterizing QT interval prolongation in early clinical development: a case study with methadone

por Dubois, Vincent F. S., Danhof, Meindert, Della Pasqua, Oscar
Publicado 2017

Pharmacokinetic Modeling of Non-Linear Brain Distribution of Fluvoxamine in the Rat

por Geldof, Marian, Freijer, Jan, van Beijsterveldt, Ludy, Danhof, Meindert
Publicado 2007

Pharmacokinetic–Pharmacodynamic Modeling of the Effectiveness and Safety of Buprenorphine and Fentanyl in Rats

por Yassen, Ashraf, Olofsen, Erik, Kan, Jingmin, Dahan, Albert, Danhof, Meindert
Publicado 2007

Long-Term Disease Control by Pomalidomide-/Dexamethasone-Based Therapy in a Patient with Advanced Multiple Myeloma: A Case Report and Review of the Literature

por Danhof, Sophia, Schreder, Martin, Strifler, Susanne, Einsele, Hermann, Knop, Stefan
Publicado 2015

Disease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women

por Berkhout, J, Stone, JA, Verhamme, KM, Danhof, M, Post, TM
Publicado 2016

CAR-T-Zell-basierte Immuntherapien in der Hämatoonkologie: Fokus auf den Einsatz in der klinischen Routine

por Steinhardt, M. J., Reinhardt, L., Luu, M., Danhof, S., Hudecek, M.
Publicado 2023

Extensions to the Visual Predictive Check to facilitate model performance evaluation

por Post, Teun M., Freijer, Jan I., Ploeger, Bart A., Danhof, Meindert
Publicado 2008

The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid

por Westerhout, Joost, Smeets, Jean, Danhof, Meindert, de Lange, Elizabeth C. M.
Publicado 2013

First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development

por Strougo, Ashley, Eissing, Thomas, Yassen, Ashraf, Willmann, Stefan, Danhof, Meindert, Freijer, Jan
Publicado 2012

Understanding the Behavior of Systems Pharmacology Models Using Mathematical Analysis of Differential Equations: Prolactin Modeling as a Case Study

por Bakshi, S, de Lange, EC, van der Graaf, PH, Danhof, M, Peletier, LA
Publicado 2016

The influence of baseline characteristics, treatment and depression on health-related quality of life in patients with multiple myeloma: a prospective observational study

por Fischer, Julia, Knop, Stefan, Danhof, Sophia, Einsele, Hermann, Keller, Daniela, Löffler, Claudia
Publicado 2022

Coping with time scales in disease systems analysis: application to bone remodeling

por Schmidt, Stephan, Post, Teun M., Peletier, Lambertus A., Boroujerdi, Massoud A., Danhof, Meindert
Publicado 2011

Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies

por Zhou, Xiang, Rasche, Leo, Kortüm, K. Martin, Danhof, Sophia, Hudecek, Michael, Einsele, Hermann
Publicado 2020

Current Limitations and Perspectives of Chimeric Antigen Receptor-T-Cells in Acute Myeloid Leukemia

por Maucher, Marius, Srour, Micha, Danhof, Sophia, Einsele, Hermann, Hudecek, Michael, Yakoub-Agha, Ibrahim
Publicado 2021