Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring

por Ryan, Timothy P., Morrison, Ryan D., Sutherland, Jeffrey J., Milne, Stephen B., Ryan, Kendall A., Daniels, J. Scott, Misra-Hebert, Anita, Hicks, J. Kevin, Vogan, Eric, Teng, Kathryn, Daly, Thomas M.
Publicado 2017

Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter

por Ennis, Elizabeth A., Wright, Jane, Retzlaff, Cassandra L., McManus, Owen B., Lin, Zhinong, Huang, Xiaofang, Wu, Meng, Li, Min, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Blakely, Randy D.
Publicado 2015

First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

por Pitchford, Lisa M., Rathmacher, John A., Fuller, John C., Daniels, J. Scott, Morrison, Ryan D., Akers, Wendall S., Abumrad, Naji N., Amarnath, Venkataraman, Currey, Patricia M., Roberts, L. Jackson, Oates, John A., Boutaud, Olivier
Publicado 2019

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of...

por Turlington, Mark, Chun, Aspen, Tomar, Sakshi, Eggler, Aimee, Grum-Tokars, Valerie, Jacobs, Jon, Daniels, J. Scott, Dawson, Eric, Saldanha, Adrian, Chase, Peter, Baez-Santos, Yahira M., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew D., Stauffer, Shaun R.
Publicado 2013

Development of a Highly Potent, Novel M(5) Positive Allosteric Modulator (PAM) Demonstrating CNS Exposure: 1-((1H-Indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piper...

por Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Noetzel, Meredith J., Cho, Hyekyung P., Lamsal, Atin, Smith, Emery, Chase, Peter, Hodder, Peter S., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicado 2014

Chemical Modulation of Mutant mGlu(1) Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics

por Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Brogan, John T., Hopkins, Corey R., Niswender, Colleen M., Rodriguez, Alice L., Venable, Daryl F., Morrison, Ryan D., Bubser, Michael, Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado 2014

Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Pep...

por Morris, Lindsey C., Nance, Kellie D., Gentry, Patrick R., Days, Emily L., Weaver, C. David, Niswender, Colleen M., Thompson, Analisa D., Jones, Carrie K., Locuson, Chuck W., Morrison, Ryan D., Daniels, J. Scott, Niswender, Kevin D., Lindsley, Craig W.
Publicado 2014

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Sel...

por Felts, Andrew S., Rodriguez, Alice L., Blobaum, Anna L., Morrison, Ryan D., Bates, Brittney S., Thompson Gray, Analisa, Rook, Jerri M., Tantawy, Mohammed N., Byers, Frank W., Chang, Sichen, Venable, Daryl F., Luscombe, Vincent B., Tamagnan, Gilles D., Niswender, Colleen M., Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A.
Publicado 2017

Selective Activation of M(4) Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

por Bubser, Michael, Bridges, Thomas M., Dencker, Ditte, Gould, Robert W., Grannan, Michael, Noetzel, Meredith J., Lamsal, Atin, Niswender, Colleen M., Daniels, J. Scott, Poslusney, Michael S., Melancon, Bruce J., Tarr, James C., Byers, Frank W., Wess, Jürgen, Duggan, Mark E., Dunlop, John, Wood, Michael W., Brandon, Nicholas J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Publicado 2014

Tetrahydronaphthyridine and Dihydronaphthyridinone Ethers As Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 5 (mGlu(5))

por Turlington, Mark, Malosh, Chrysa, Jacobs, Jon, Manka, Jason T., Noetzel, Meredith J., Vinson, Paige N., Jadhav, Satyawan, Herman, Elizabeth J., Lavreysen, Hilde, Mackie, Claire, Bartolomé-Nebreda, José M., Conde-Ceide, Susana, Martín-Martín, M. Luz, Tong, Han Min, López, Silvia, MacDonald, Gregor J., Steckler, Thomas, Daniels, J. Scott, Weaver, C. David, Niswender, Colleen M., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Stauffer, Shaun R.
Publicado 2014