An automated computational approach to kinetic model discrimination and parameter estimation

por Taylor, Connor J., Seki, Hikaru, Dannheim, Friederike M., Willis, Mark J., Clemens, Graeme, Taylor, Brian A., Chamberlain, Thomas W., Bourne, Richard A.
Publicado 2021

All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading

por Dannheim, Friederike M., Walsh, Stephen J., Orozco, Carolina T., Hansen, Anders Højgaard, Bargh, Jonathan D., Jackson, Sophie E., Bond, Nicholas J., Parker, Jeremy S., Carroll, Jason S., Spring, David R.
Publicado 2022

Divinylpyrimidine reagents generate antibody–drug conjugates with excellent in vivo efficacy and tolerability

por Walsh, Stephen J., Omarjee, Soleilmane, Dannheim, Friederike M., Couturier, Dominique-Laurent, Bexheti, Dorentina, Mendil, Lee, Cronshaw, Gemma, Fewster, Toby, Gregg, Charlotte, Brodie, Cara, Miller, Jodi L., Houghton, Richard, Carroll, Jason S., Spring, David R.
Publicado 2022