Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules

por Papadaki, Georgia F., Ani, Omar, Florio, Tyler J., Young, Michael C., Danon, Julia N., Sun, Yi, Dersh, Devin, Sgourakis, Nikolaos G.
Publicado 2023

Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

por Sun, Yi, Papadaki, Georgia F., Devlin, Christine A., Danon, Julia N., Young, Michael C., Winters, Trenton J., Burslem, George M., Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2023

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

por Sun, Yi, Young, Michael C., Woodward, Claire H., Danon, Julia N., Truong, Hau V., Gupta, Sagar, Winters, Trenton J., Font-Burgada, Joan, Burslem, George M., Sgourakis, Nikolaos G.
Publicado 2023