Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

por Paré, Martin, Darini, Cédric Y., Yao, Xi, Chignon-Sicard, Bérengère, Rekima, Samah, Lachambre, Simon, Virolle, Virginie, Aguilar-Mahecha, Adriana, Basik, Mark, Dani, Christian, Ladoux, Annie
Publicado 2020

Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

por Krishnamoorthy, Jothilatha, Tenkerian, Clara, Gupta, Jyotsana, Ghaddar, Nour, Wang, Shuo, Darini, Cedric, Staschke, Kirk A., Ghosh, Abhishek, Gandin, Valentina, Topisirovic, Ivan, Kristof, Arnold S., Hatzoglou, Maria, Simos, George, Koromilas, Antonis E.
Publicado 2018

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy

por Darini, Cedric, Ghaddar, Nour, Chabot, Catherine, Assaker, Gloria, Sabri, Siham, Wang, Shuo, Krishnamoorthy, Jothilatha, Buchanan, Marguerite, Aguilar-Mahecha, Adriana, Abdulkarim, Bassam, Deschenes, Jean, Torres, Jose, Ursini-Siegel, Josie, Basik, Mark, Koromilas, Antonis E.
Publicado 2019

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

por Ghaddar, Nour, Wang, Shuo, Woodvine, Bethany, Krishnamoorthy, Jothilatha, van Hoef, Vincent, Darini, Cedric, Kazimierczak, Urszula, Ah-son, Nicolas, Popper, Helmuth, Johnson, Myriam, Officer, Leah, Teodósio, Ana, Broggini, Massimo, Mann, Koren K., Hatzoglou, Maria, Topisirovic, Ivan, Larsson, Ola, Le Quesne, John, Koromilas, Antonis E.
Publicado 2021