Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

por Kumar, Rajnish, Nordberg, Agneta, Darreh-Shori, Taher
Publicado 2016

Novel ligands of Choline Acetyltransferase designed by in silico molecular docking, hologram QSAR and lead optimization

por Kumar, Rajnish, Långström, Bengt, Darreh-Shori, Taher
Publicado 2016

Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening

por Kumar, Rajnish, Kumar, Amit, Långström, Bengt, Darreh-Shori, Taher
Publicado 2017

CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment

por Karami, Azadeh, Darreh-Shori, Taher, Schultzberg, Marianne, Eriksdotter, Maria
Publicado 2021

Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced chol...

por Sinclair, Lindsey Isla, Kumar, Amit, Darreh-Shori, Taher, Love, Seth
Publicado 2019

Allosteric Binding Sites of Aβ Peptides on the Acetylcholine Synthesizing Enzyme ChAT as Deduced by In Silico Molecular Modeling

por Baidya, Anurag TK, Kumar, Amit, Kumar, Rajnish, Darreh-Shori, Taher
Publicado 2022

Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation

por Malmsten, Linn, Vijayaraghavan, Swetha, Hovatta, Outi, Marutle, Amelia, Darreh-Shori, Taher
Publicado 2014

Biomarkers in Alzheimer's Disease and Lewy Body Disorders with Dementia

por Leyhe, Thomas, Darreh-Shori, Taher, Laske, Christoph, Mielke, Michelle M., Maetzler, Walter
Publicado 2013

Soluble Aβ42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase

por Kumar, Amit, Lana, Erica, Kumar, Rajnish, Lithner, Christina Unger, Darreh-Shori, Taher
Publicado 2018

CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

por Karami, Azadeh, Eriksdotter, Maria, Kadir, Ahmadul, Almkvist, Ove, Nordberg, Agneta, Darreh-Shori, Taher
Publicado 2019

Homomeric and Heteromeric Aβ Species Exist in Human Brain and CSF Regardless of Alzheimer’s Disease Status and Risk Genotype

por Lana, Erica, Gellerbring, Anna, Jung, Sabrina, Nordberg, Agneta, Unger Lithner, Christina, Darreh-Shori, Taher
Publicado 2019

Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers

por Mitra, Sumonto, Turconi, Giorgio, Darreh-Shori, Taher, Mätlik, Kärt, Aquilino, Matilde, Eriksdotter, Maria, Andressoo, Jaan-Olle
Publicado 2021

Association of glial and neuronal degeneration markers with Alzheimer’s disease cerebrospinal fluid profile and cognitive functions

por Teitsdottir, Unnur D., Jonsdottir, Maria K., Lund, Sigrun H., Darreh-Shori, Taher, Snaedal, Jon, Petersen, Petur H.
Publicado 2020

Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects

por Teitsdottir, Unnur D., Darreh-Shori, Taher, Lund, Sigrun H., Jonsdottir, Maria K., Snaedal, Jon, Petersen, Petur H.
Publicado 2022

Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App(NL−G−F) knock-in Alzheimer mice

por Tambaro, Simone, Mitra, Sumonto, Gera, Ruchi, Linderoth, Bengt, Wahlberg, Lars U., Darreh-Shori, Taher, Behbahani, Homira, Nilsson, Per, Eriksdotter, Maria
Publicado 2023

Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzhei...

por Kadir, Ahmadul, Marutle, Amelia, Gonzalez, Daniel, Schöll, Michael, Almkvist, Ove, Mousavi, Malahat, Mustafiz, Tamanna, Darreh-Shori, Taher, Nennesmo, Inger, Nordberg, Agneta
Publicado 2011

Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer’s Disease Brain

por Darreh-Shori, Taher, Rezaeianyazdi, Sareh, Lana, Erica, Mitra, Sumonto, Gellerbring, Anna, Karami, Azadeh, Bogdanovic, Nenad, Lithner, Christina Unger, Winblad, Bengt, Behbahani, Homira
Publicado 2018

Fast Alpha Activity in EEG of Patients With Alzheimer’s Disease Is Paralleled by Changes in Cognition and Cholinergic Markers During Encapsulated Cell Biodelivery of Nerve Growth F...

por Eyjolfsdottir, Helga, Koenig, Thomas, Karami, Azadeh, Almqvist, Per, Lind, Göran, Linderoth, Bengt, Wahlberg, Lars, Seiger, Åke, Darreh-Shori, Taher, Eriksdotter, Maria, Jelic, Vesna
Publicado 2022

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

por Vijayaraghavan, Swetha, Karami, Azadeh, Aeinehband, Shahin, Behbahani, Homira, Grandien, Alf, Nilsson, Bo, Ekdahl, Kristina N., Lindblom, Rickard P. F., Piehl, Fredrik, Darreh-Shori, Taher
Publicado 2013

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

por Aeinehband, Shahin, Lindblom, Rickard P. F., Al Nimer, Faiez, Vijayaraghavan, Swetha, Sandholm, Kerstin, Khademi, Mohsen, Olsson, Tomas, Nilsson, Bo, Ekdahl, Kristina Nilsson, Darreh-Shori, Taher, Piehl, Fredrik
Publicado 2015